Clean Technology (청정기술)

The Korean Society of Clean Technology (한국청정기술학회)
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Detection of Intracellular Free Metal Ions with Molecular Two-Photon Sensors

이광자 분자센서를 이용한 생체 내 금속이온 검출

  • 김환명 (아주대학교 에너지시스템학부)
  • Received : 2011.07.18
  • Accepted : 2011.08.13
  • Published : 2011.09.30
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Abstract

Two-photon microscopy (TPM) is attracting much attention in biological imaging due to the capability of imaging deep inside the living tissues for a long period of time. For maximum utilization of TPM, it is essential to develop efficient twophoton sensors. Regarding this, many research groups are developing two-photon sensors for specific applications. In this review, we summarize recent results on selected examples of two-photon sensors for intracellular free metal ions in the live cells and tissues to provide a guideline for various imaging applications.

이광자 현미경(two-photon microscopy)은 다양한 생명현상을 살아있는 조직의 깊은 곳에서 관찰할 수 있다는 장점 때문에 차세대 영상기술로 발전하고 있다. 이에 따라 다양한 목적에 사용할 수 있는 이광자 센서의 개발이 활발하게 진행 중이다. 이 총설에서는 금속이온 이광자 센서에 관한 최근의 연구 결과를 소개하고자 한다.

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