Korean Circulation Journal

The Korean Society of Cardiology (대한심장학회)
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A Case of Sparganosis That Presented as a Recurrent Pericardial Effusion

  • Lee, Ju-Hee (Department of Internal Medicine, Chungbuk National University School of Medicine) ;
  • Kim, Gi-Hyun (Department of Internal Medicine, Chungbuk National University School of Medicine) ;
  • Kim, Sang-Min (Department of Internal Medicine, Chungbuk National University School of Medicine) ;
  • Lee, Sang-Yeub (Department of Internal Medicine, Chungbuk National University School of Medicine) ;
  • Lee, Won-Yik (Department of Internal Medicine, Chungbuk National University School of Medicine) ;
  • Bae, Jang-Whan (Department of Internal Medicine, Chungbuk National University School of Medicine) ;
  • Shin, Kyung-Sub (Department of Laboratory Medicine, Chungbuk National University School of Medicine) ;
  • Hwang, Kyung-Kuk (Department of Internal Medicine, Chungbuk National University School of Medicine) ;
  • Kim, Dong-Won (Department of Internal Medicine, Chungbuk National University School of Medicine) ;
  • Cho, Myeong-Chan (Department of Internal Medicine, Chungbuk National University School of Medicine)
  • Published : 2011.01.30
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Abstract

Sparganosis is caused by a larval tapeworm of the genus Spirometra, which commonly invades subcutaneous tissue, but less frequently invades muscle, intestines, spinal cord, and the peritoneopleural cavity. The authors managed a female patient who presented with a recurrent pericardiopleural effusion and peripheral eosinophilia. The anti-sparganum-specific IgG serum level was significantly higher than normal control levels. In this patient, sparganosis was caused by the ingestion of raw frogs in an effort to control her thyroid disease. The recurrent pericardiopleural effusion and peripheral eosinophilia were controlled by 3 consecutive doses of praziquantel (75 mg/kg/day). The patient is doing well 4 years after presentation. Sparganosis should be considered a rare, but possible cause of recurrent pericardial effusion and peripheral eosinophilia. Immunoserologic testing using enzyme linked immunosorbent assays can be helpful in diagnosing human sparganosis, especially in cases without a subcutaneous lump or mass. Praziquantel is an alternative treatment for sparganosis in surgically-unresectable cases.

Keywords

References

  1. Sun T. Parasitic Disorders: Pathology, Diagnosis, and Management. 2nd ed. Pennsylvania: Williams & Wilkins;1999. p.285-90.
  2. Mueller JF. The biology of Spirometra. J Parasitol 1974;60:3-14.
  3. Cho SY, Bae JH, Seo BS. Some aspects of human sparganosis in Korea. Korean J Parasitol 1975;13:60-77. https://doi.org/10.3347/kjp.1975.13.1.60
  4. Tanaka S, Maruyama H, Ishiwata K, et al. A case report of pleural sparganosis. Parasitol Int 1997;46:73-5. https://doi.org/10.1016/S1383-5769(97)00001-9
  5. Ishii H, Mukae H, Inoue Y, et al. A rare case of eosinophilic pleuritis due to sparganosis. Intern Med 2001;40:783-5. https://doi.org/10.2169/internalmedicine.40.783
  6. Kamiya H, Shimizu H, Kobayashi N, Kudo K. A case of sparganosis with eosinophilic pleural effusion. Nihon Kokyuki Gakkai Zasshi 2004;42:1019-23.
  7. Shimada M, Matsumura K, Aoki Y, et al. Two cases of sparganosis having onsets of pleural effusion. Jpn J Parasitol 1989;38:145.
  8. Yamasaki H, Araki K, Aoki T. Parasitic diseases examined during the past 16 years in the Department of Parasitology, Juntendo University School of Medicine. Juntendo Igaku 1994;40:262-79. https://doi.org/10.14789/pjmj.40.262
  9. Kim DH, Yi IH, Youn HC, et al. Pleural sparganosis: a case report. Korean J Thorac Cardiovasc Surg 2006;39:502-4.
  10. Koh TW, Lee JW, Sohn DS, et al. Empyema thoracis associated with sparganosis: a case report. Korean J Thorac Cardiovasc Surg 1988; 21:761-5.
  11. Ha JK, Hong TJ, Chun KJ, et al. Biochemical analysis of serum and pericardial fluid in patients with hemorrhagic pericardial effusion. Korean Circ J 2003;33:227-32. https://doi.org/10.4070/kcj.2003.33.3.227
  12. Eo WK, Lee SK, Choi CJ, et al. Clinical studies on the etiology and clinical course of pericardial effusions. Korean Circ J 1990;20:211-9. https://doi.org/10.4070/kcj.1990.20.2.211
  13. Voller A, Bidwell DE, Bartlett A. The Enzyme-Linked Immunosorbent Assay. London: Nuffield laboratories of comparative medicine; 1994. p.19-41.
  14. Min DY. Cestode infections in Korea. Korean J Parasitol 1990;28:123-44. https://doi.org/10.3347/kjp.1990.28.Suppl.123
  15. Sim S, You JK, Lee IY, Im KI, Yong TS. A case of breast sparganosis. Korean J Parasitol 2002;40:187-9. https://doi.org/10.3347/kjp.2002.40.4.187
  16. Kim HJ, Park SH, Yum DJ, et al. A case of sparganosis in the submandibular triangle. J Clin Otolaryngol Head Neck Surg 2005;16:330-3.
  17. Cho KJ, Lee HS, Chi JG. Intramural sparganosis manifested as intestinal obstruction. J Korean Med Sci 1987;2:137-9. https://doi.org/10.3346/jkms.1987.2.2.137
  18. Kim H, Kim SI, Cho SY. Serological diagnosis of human sparganosis by means of micro-ELISA. Korean J Parasitol 1984;22:222-8. https://doi.org/10.3347/kjp.1984.22.2.222
  19. Yeo IS, Yong TS, Im K. Serodiagnosis of human sparganosis by a monoclonal antibody-based competition ELISA. Yonsei Med J 1994;35:43-8.
  20. Sohn WM, Hong ST, Chai JY, Lee SH. Infectivity of the sparganum treated by praziquantel, gamma-irradiation and mechanical cutting. Korean J Parasitol 1993;31:135-9. https://doi.org/10.3347/kjp.1993.31.2.135

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