DOI QR코드

DOI QR Code

Various Tumor-Mimicking Lesions in the Musculoskeletal System: Causes and Diagnostic Approach

  • Kim, Sue-Yon (Department of Radiology, Kyung Hee University Medical Center) ;
  • Park, Ji-Seon (Department of Radiology, Kyung Hee University Medical Center) ;
  • Ryu, Kyung-Nam (Department of Radiology, Kyung Hee University Medical Center) ;
  • Jin, Wook (Department of Radiology, East-West Neo Medical Center, Kyung Hee University) ;
  • Park, So-Young (Department of Radiology, East-West Neo Medical Center, Kyung Hee University)
  • Published : 2011.04.01

Abstract

Tumor-mimicking lesions in the musculoskeletal system can be defined as lesions mistaken as tumors due to the presence of palpation upon physical examination or a tumor-like appearance upon radiological examination. Moreover, tumor-mimicking lesions show diverse etiologies and anatomic locations. We illustrated the various tumor-mimicking lesions involving bone and soft tissue. In this review, the tumor-mimicking lesions were classified into those based on clinical examination and those based on radiological examination in musculoskeletal radiology. Awareness of the various causes of tumor-mimicking lesions, correctly obtaining clinical information, and the proper selection of imaging modality are important for the differentiation of tumor-mimicking lesions from true neoplasms.

Keywords

References

  1. Vessal S, Rai SB. Accessory extensor carpi radialis brevis muscle, a pseudomass of the distal forearm: ultrasound and MR appearances - case report and literature review. Clin Radiol 2006;61:442-445 https://doi.org/10.1016/j.crad.2005.12.008
  2. Mattle HP, Hess CW, Ludin HP, Mumenthaler M. Isolated muscle hypertrophy as a sign of radicular or peripheral nerve injury. J Neurol Neurosurg Psychiatry 1991;54:325-329 https://doi.org/10.1136/jnnp.54.4.325
  3. Polesuk BS, Helms CA. Hypertrophied palmaris longus muscle, a pseudomass of the forearm: MR appearance--case report and review of the literature. Radiology 1998;207:361-362 https://doi.org/10.1148/radiology.207.2.9577481
  4. Anderson MW, Benedetti P, Walter J, Steinberg DR. MR appearance of the extensor digitorum manus brevis muscle: a pseudotumor of the hand. AJR Am J Roentgenol 1995;164:1477-1479 https://doi.org/10.2214/ajr.164.6.7754896
  5. Capelastegui A, Astigarraga E, Fernandez-Canton G, Saralegui I, Larena JA, Merino A. Masses and pseudomasses of the hand and wrist: MR findings in 134 cases. Skeletal Radiol 1999;28:498-507 https://doi.org/10.1007/s002560050553
  6. Kalbermatten DF, Kalbermatten NT, Hertel R. Cotton-induced pseudotumor of the femur. Skeletal Radiol 2001;30:415-417 https://doi.org/10.1007/s002560100358
  7. Resnick D. Diagnosis of bone and joint disorders, 3rd ed. Philadelphia: Saunders, 1995
  8. Mellado JM, Ramos A, Salvado E, Camins A, Danus M, Sauri A. Accessory ossicles and sesamoid bones of the ankle and foot: imaging findings, clinical significance and differential diagnosis. Eur Radiol 2003;13 Suppl 6:L164-L177 https://doi.org/10.1007/s00330-003-2011-8
  9. Anderson SE, Johnston JO, Steinbach LS. Pseudotumors of the shoulder invited review. Eur J Radiol 2008;68:147-158 https://doi.org/10.1016/j.ejrad.2008.02.030
  10. Useche JN, de Castro AM, Galvis GE, Mantilla RA, Ariza A. Use of US in the evaluation of patients with symptoms of deep venous thrombosis of the lower extremities. Radiographics 2008;28:1785-1797 https://doi.org/10.1148/rg.286085513
  11. Ramon FA, Degryse HR, De Schepper AM, Van Marck EA. Calcific tendinitis of the vastus lateralis muscle. A report of three cases. Skeletal Radiol 1991;20:21-23 https://doi.org/10.1007/BF00243716
  12. Thiele RG, Schlesinger N. Diagnosis of gout by ultrasound. Rheumatology (Oxford) 2007;46:1116-1121 https://doi.org/10.1093/rheumatology/kem058
  13. Schwartzfarb EM, Hametti JM, Romanelli P, Ricotti C. Foreign body granuloma formation secondary to silicone injection. Dermatol Online J 2008;14:20
  14. Catalano OA, Dal Pozzo F, Grifi DN, Menchi I, Rosenthal DI. Paraffinoma of the knee. Skeletal Radiol 2003;32:485-488 https://doi.org/10.1007/s00256-003-0640-2
  15. De Wilde V, De Maeseneer M, Lenchik L, Van Roy P, Beeckman P, Osteaux M. Normal osseous variants presenting as cystic or lucent areas on radiography and CT imaging: a pictorial overview. Eur J Radiol 2004;51:77-84 https://doi.org/10.1016/S0720-048X(03)00180-3
  16. Hammond I, Sheikh A, Rasuli P, Souza CA. Vertebral pseudolesion on lateral chest radiograph. AJR Am J Roentgenol 2008;190:W240-W241 https://doi.org/10.2214/AJR.07.3304
  17. Kransdorf MJ, Meis JM. From the archives of the AFIP. Extraskeletal osseous and cartilaginous tumors of the extremities. Radiographics 1993;13:853-884 https://doi.org/10.1148/radiographics.13.4.8356273
  18. De Smet AA, Norris MA, Fisher DR. Magnetic resonance imaging of myositis ossifi cans: analysis of seven cases. Skeletal Radiol 1992;21:503-507 https://doi.org/10.1007/BF00195231
  19. Kransdorf MJ, Meis JM, Jelinek JS. Myositis ossifi cans: MR appearance with radiologic-pathologic correlation. AJR Am J Roentgenol 1991;157:1243-1248 https://doi.org/10.2214/ajr.157.6.1950874
  20. Gaeta M, Mazziotti S, Minutoli F, Genitori A, Toscano A, Rodolico C, et al. MR imaging findings of focal myositis: a pseudotumour that may mimic muscle neoplasm. Skeletal Radiol 2009;38:571-578 https://doi.org/10.1007/s00256-009-0664-3
  21. Kransdorf MJ, Temple HT, Sweet DE. Focal myositis. Skeletal Radiol 1998;27:283-287 https://doi.org/10.1007/s002560050382
  22. Son JM, Jee WH, Jung CK, Kim SI, Ha KY. Aspergillus spondylitis involving the cervico-thoraco-lumbar spine in an immunocompromised patient: a case report. Korean J Radiol 2007;8:448-451 https://doi.org/10.3348/kjr.2007.8.5.448
  23. Urban BA, Fishman EK, Goldman SM, Scott WW Jr, Jones B, Humphrey RL, et al. CT evaluation of amyloidosis: spectrum of disease. Radiographics 1993;13:1295-1308 https://doi.org/10.1148/radiographics.13.6.8290725
  24. Park JS, Ryu KN, Hong HP, Park YK, Chun YS, Yoo MC. Focal osteolysis in total hip replacement: CT findings. Skeletal Radiol 2004;33:632-640 https://doi.org/10.1007/s00256-004-0812-8

Cited by

  1. Soft-Tissue Lesions: When Can We Exclude Sarcoma? vol.199, pp.6, 2012, https://doi.org/10.2214/ajr.12.8719
  2. Ossified soft tissue recurrence of giant cell tumor of the bone: four case reports with follow-up radiographs, CT, ultrasound, and MR images vol.43, pp.10, 2011, https://doi.org/10.1007/s00256-014-1898-2
  3. Distinguishing bone and soft tissue infections mimicking sarcomas requires multimodal multidisciplinary team assessment vol.101, pp.6, 2011, https://doi.org/10.1308/rcsann.2019.0040