Korean Journal of Radiology

The Korean Society of Radiology (대한영상의학회)
권호 표지
DOI QR코드

DOI QR Code

Acinar Cell Cystadenoma (Acinar Cystic Transformation) of the Pancreas: the Radiologic-Pathologic Features

  • Gumus, Mehmet (Department of Radiology, Ataturk Training and Research Hospital) ;
  • Ugras, Serdar (Department of Pathology, Selcuk University, Selcuklu Medical Faculty) ;
  • Algin, Oktay (Department of Radiology, Ataturk Training and Research Hospital) ;
  • Gundogdu, Haldun (Department of General Surgery, Ataturk Training and Research Hospital)
  • Published : 2011.02.01
⟨ Previous Next ⟩

Abstract

Acinar cystic transformation of the pancreas is also known as acinar cell cystadenoma (ACC), and this is an extremely rare benign lesion that was fi rst described in April 2002. We report here on a case of a previously asymptomatic patient with pancreatic ACC and this was diagnosed by computed tomography (CT) and magnetic resonance imaging (MRI). To the best of our knowledge, there is no previous report concerning the CT or MRI features of ACC in the medical literature. We present here the CT, MRI and pathological fi ndings of pancreatic ACC.

Keywords

References

  1. Hamilton SR, Aaltonen LA. Pathology and genetics of tumours of digestive system. WHO classifi cation of tumours. Lyon, France: IARC Press 2000
  2. Huang Y, Cao YF, Lin JL, Gao F, Li F. Acinar cell cystadenocarcinoma of the pancreas in a 4-year-old child. Pancreas 2006;33:311-312 https://doi.org/10.1097/01.mpa.0000229011.70161.d9
  3. Solcia E, Capella C, Kloppel G. Tumors of the pancreas. Atlas of tumor pathology, 3rd Series, Fascicle 20. Washington, DC: AFIP 1997;103-114
  4. Adsay NV. Cystic lesions of the pancreas. Mod Pathol 2007;20:S71-S93 https://doi.org/10.1038/modpathol.3800706
  5. Cantrell BB, Cubilla AL, Erlandson RA, Fortner J, Fitzgerald PJ. Acinar cell cystadenocarcinoma of human pancreas. Cancer 1981;47:410-416 https://doi.org/10.1002/1097-0142(19810115)47:2<410::AID-CNCR2820470232>3.0.CO;2-D
  6. Albores-Saavedra J. Acinar cystadenoma of the pancreas: a previously undescribed tumor. Ann Diagn Pathol 2002;6:113-115 https://doi.org/10.1053/adpa.2002.32379
  7. Zamboni G, Terris B, Scarpa A, Kosmahl M, Capelli P, Klimstra DS, et al. Acinar cell cystadenoma of the pancreas: a new entity? Am J Surg Pathol 2002;26:698-704 https://doi.org/10.1097/00000478-200206000-00002
  8. Chatelain D, Paye F, Mourra N, Scoazec JY, Baudrimont M, Parc R, et al. Unilocular acinar cell cystadenoma of the pancreas an unusual acinar cell tumor. Am J Clin Pathol 2002;118:211-214 https://doi.org/10.1309/JQQ1-06NY-0F3J-PEU9
  9. Couvelard A, Terris B, Hammel P, Palazzo L, Belghiti J, Levy P, et al. Acinar cystic transformation of the pancreas (or acinar cell cystadenoma), a rare and recently described entity. Ann Pathol 2002;22:397-400 [French]
  10. Tatli S, Mortele KJ, Levy AD, Glickman JN, Ros PR, Banks PA, et al. CT and MRI features of pure acinar cell carcinoma of the pancreas in adults. AJR Am J Roentgenol 2005;184:511-519 https://doi.org/10.2214/ajr.184.2.01840511
  11. Brugge WR. Cystic neoplasms of the pancreas. Endoscopic oncology, Chapter 24. Totowa, New Jersey: Humana Press Inc, 2006:289-294
  12. Sahani DV, Kadavigere R, Saokar A, Fernandez-del Castillo C, Brugge WR, Hahn PF. Cystic pancreatic lesions: a simple imaging-based classifi cation system for guiding management. Radiographics 2005;25:1471-1484 https://doi.org/10.1148/rg.256045161
  13. Acar M, Tatli S. Cystic tumors of the pancreas: a radiological perspective. Diagn Interv Radiol 2010 [Epub ahead of print] DOI: 10.4261/1305-3825.DIR.3254-09.1
  14. Brugge WR, Lauwers GY, Sahani D, Fernandez-del Castillo C, Warshaw AL. Cystic neoplasms of the pancreas. N Engl J Med 2004;351:1218-1226 https://doi.org/10.1056/NEJMra031623
  15. Kazumori H, Sizuku T, Ueki T, Uchida Y, Yamamoto S. Lymphoepithelial cyst of the pancreas. J Gastroenterol 1997;32:700-703 https://doi.org/10.1007/BF02934125
  16. Chiou YY, Chiang JH, Hwang JI, Yen CH, Tsay SH, Chang CY. Acinar cell carcinoma of the pancreas: clinical and computed tomography manifestations. J Comput Assist Tomogr 2004;28:180-186 https://doi.org/10.1097/00004728-200403000-00005
  17. Chung WJ, Byun JH, Lee SS, Lee MG. Imaging findings in a case of mixed acinar-endocrine carcinoma of the pancreas. Korean J Radiol 2010;11:378-381 https://doi.org/10.3348/kjr.2010.11.3.378

Cited by

  1. Periampullary localized pancreatic intraepithelial neoplasia-3 (PanIN-3): evaluation with contrast-enhanced MR cholangiography (MRCP) vol.45, pp.4, 2011, https://doi.org/10.2478/v10019-011-0035-2
  2. Acinar Cystadenoma of the Pancreas: A Clinicopathologic Study of 10 Cases Including Multilocular Lesions With Mural Nodules vol.36, pp.11, 2011, https://doi.org/10.1097/pas.0b013e318265fa4b
  3. Acinar Cell Cystadenoma of the Pancreas: Report of Three Cases and Literature Review vol.17, pp.7, 2011, https://doi.org/10.1007/s11605-013-2199-0
  4. Molecular analysis of pancreatic acinar cell cystadenomas: Evidence of a non-neoplastic nature vol.8, pp.2, 2011, https://doi.org/10.3892/ol.2014.2163
  5. CT and MR imaging of multilocular acinar cell cystadenoma: comparison with branch duct intraductal papillary mucinous neoplasia (IPMNs) vol.24, pp.9, 2011, https://doi.org/10.1007/s00330-014-3248-0
  6. A resected case of symptomatic acinar cell cystadenoma of the pancreas displacing the main pancreatic duct vol.2, pp.None, 2016, https://doi.org/10.1186/s40792-016-0166-1
  7. Fifteen-Year Follow-Up of a Patient with Acinar Cystic Transformation of the Pancreas and Literature Review vol.2020, pp.None, 2011, https://doi.org/10.1155/2020/8847550
  8. Pancreatic Acinar Cell Cystadenoma Mimicking Pancreatic Serous Cystadenoma vol.78, pp.2, 2011, https://doi.org/10.4166/kjg.2021.044