대한영상의학회지 (Journal of the Korean Society of Radiology)

  • 제64권1호
  • /
  • Pages.91-95
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  • 2011
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  • 1738-2637(pISSN)
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  • 2288-2928(eISSN)
대한영상의학회 (The Korean Society of Radiology)
권호 표지

소아에서 발생한 KIT 음성 위장관간질종양: 증례 보고

KIT-negative Gastrointestinal Stromal Tumor in a Child: A Case Report

  • 임세웅 (원광대학교 의과대학 영상의학과) ;
  • 이영환 (원광대학교 의과대학 영상의학과) ;
  • 박상현 (원광대학교 의과대학 영상의학과) ;
  • 최두영 (원광대학교 의과대학 소아청소년과) ;
  • 최금하 (원광대학교 의과대학 병리과)
  • Lim, Se-Woong (Department of Radiology, Wonkwang University School of Medicine and Hospital) ;
  • Lee, Young-Hwan (Department of Radiology, Wonkwang University School of Medicine and Hospital) ;
  • Park, Sang-Hyeon (Department of Radiology, Wonkwang University School of Medicine and Hospital) ;
  • Choi, Du-Young (Department of Pediatirics, Wonkwang University School of Medicine and Hospital) ;
  • Choi, Geum-Ha (Department of Pathology, Wonkwang University School of Medicine and Hospital)
  • 발행 : 2011.01.01
⟨ 이전 논문 다음 논문 ⟩

초록

저자들은 12세 여아의 위에서 발생한 KIT 음성 위장관간질종양(GIST)의 영상소견을 보고하고자 한다. 초음파, CT, MR 등 영상의학 검사에서 위벽에서 기원한 큰 외장형 종괴가 보였고 내부는 고형성 부위와 낭성 부위가 혼합되어 있었다. 낭성 부위는 주로 종양의 바깥쪽에 있었고 조직병리학적으로 점액성 변성 및 출혈로 확인되었다. 종양의 고형 부위는 상피양 세포 및 전형적인 방추형 세포로 구성되어 있었다. KIT 음성 위장관간질종양은 드물지만, 큰 외장형 종괴가 내부에 불균일한 고형성 부위와 다양한 정도의 낭성 부위를 포함하고 있고, 특히 낭성 부위가 종양의 변연부에 있을 때 KIT 음성 위장관간질종양을 고려해 볼 수 있다.

We report here on the imaging findings of the case of KIT-negative gastrointestinal stromal tumor (GIST) in the stomach of a 12-year-old girl. Radiologic studies revealed the presence of a huge exophytic growing mass that originated from the gastric wall and this mass consisted of solid and cystic components on USG, CT and MR. The cystic regions were mainly located at the periphery of the mass and they were revealed to be myxoid degeneration and hemorrhage on histopathologic examination. The tumor consisted of epithelioid and typical spindle cells and they showed negative immunoreactivity for KIT. Although KIT-negative GISTs are rare, they can be considered in the differential diagnosis when a large heterogeneous extraluminal mass that contains solid portions and various degrees of peripheral cystic regions is observed.

키워드

참고문헌

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