The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
권호 표지

A Case of Native Valve Infective Endocarditis Caused by Staphylococcus lugdunensis

자연 판막에서 발생한 Staphylococcus lugdunensis에 의한 감염성 심내막염 1예

  • Cho, Hwan-Jin (Division of Cardiology, Department of Internal Medicine, Ulsan Hospital) ;
  • Seol, Sang-Hoon (Division of Cardiology, Department of Internal Medicine, Paik Hospital, Inje University College of Medicine) ;
  • Park, Sang-Yool (Division of Cardiology, Department of Internal Medicine, Paik Hospital, Inje University College of Medicine) ;
  • Jun, Hyun-Soo (Division of Cardiology, Department of Internal Medicine, Paik Hospital, Inje University College of Medicine) ;
  • Kim, Dong-Kie (Division of Cardiology, Department of Internal Medicine, Paik Hospital, Inje University College of Medicine) ;
  • Kim, Doo-Il (Division of Cardiology, Department of Internal Medicine, Paik Hospital, Inje University College of Medicine) ;
  • Kim, Dong-Soo (Division of Cardiology, Department of Internal Medicine, Paik Hospital, Inje University College of Medicine)
  • 조환진 (울산병원 심장내과) ;
  • 설상훈 (인제대학교 의과대학 부산백병원 심장내과) ;
  • 박상율 (인제대학교 의과대학 부산백병원 심장내과) ;
  • 전현수 (인제대학교 의과대학 부산백병원 심장내과) ;
  • 김동기 (인제대학교 의과대학 부산백병원 심장내과) ;
  • 김두일 (인제대학교 의과대학 부산백병원 심장내과) ;
  • 김동수 (인제대학교 의과대학 부산백병원 심장내과)
  • Published : 2011.02.01
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Abstract

A 37-year-old woman presented to our hospital with a 1-month history of fever. She also complained of lower leg pain. Transthoracic echocardiography showed large vegetations on the mitral valve leaflets. Staphylococcus lugdunensis was isolated from blood cultures. She was diagnosed with infectious endocarditis due to S. lugdunensis and was treated with antibiotics and surgery. Infective endocarditis caused by S. lugdunensis can be invasive and often resembles endocarditis due to Staphylococcus aureus. Thus, whenever this organism is found in patients with endocarditis, early surgical treatment of the infected valve should be considered.

S. lugdunensis 감염성 심내막염은 국내에서 거의 보고가 없었고, 매우 드물지만 심한 합병증 및 높은 사망률을 보이는 질환이다. 저자들은 항생제 및 수술적 치료로 완치된 자연 판막에서 발생한 S. lugdunensis 감염성 심내막염 1예를 경험하였기에 이를 문헌고찰과 함께 보고하는 바이다.

Keywords

References

  1. Freney J, Brun Y, Bes M, et al. Staphylococcus lugdunensis sp. nov. and Staphylococcus schleiferi sp. nov., two species from human clinical specimens. Int J Syst Bacteriol 1988;38:168-172. https://doi.org/10.1099/00207713-38-2-168
  2. Vandenesch F, Etienne J, Reverdy ME, Eykyn SJ. Endocarditis due to Staphylococcus lugdunensis: report of 11 cases and review. Clin Infect Dis 1993;17:871-876. https://doi.org/10.1093/clinids/17.5.871
  3. 최성호, 박현구, 변승운, et al. Staphylococcus lugdunensis에 의한 감염성 심내막염 1예. 감염과 화학요법 2006;38:277-281.
  4. Kim ES, Joo EJ, Ha YE, et al. Clinical characteristics of infective endocarditis caused by Staphylococcus aureus: a 12-year experience in a tertiary-care hospital. Korean J Med 2009;76:329-337.
  5. Shin SY, Park YS, Choi JY, et al. Changing trends of infective endocarditis according to the change in health care system in Korea. Korean J Med 2005;68:157-167.
  6. Kim MK, Song JK, Kang DH, et al. Recent trends and clinical outcomes of infective endocarditis. Korean J Med 2000;58:28-38.
  7. Patel R, Piper KE, Rouse MS, Uhl JR, Cockerill FR 3rd, Steckelberg JM. Frequency of isolation of Staphylococcus lugdunensis among staphylococcal isolates causing endocarditis: a 20-year experience. J Clin Microbiol 2000;38:4262-4263.
  8. Anguera I, Del Rio A, Miro JM, Staphylococcus lugdunensis infective endocarditis: description of 10 cases and analysis of native valve, prosthetic valve and pacemaker lead endocarditis clinical profiles. Heart 2005;91:e10. https://doi.org/10.1136/hrt.2004.040659
  9. Ebright JR, Penugonda N, Brown W. Clinical experience with Staphylococcus lugdunensis bacteremia: a retrospective analysis. Diagn Microbiol Infect Dis 2004;48:17-21. https://doi.org/10.1016/j.diagmicrobio.2003.08.008
  10. Van Hoovels L, De Munter P, Colaert J, et al. Three cases of destructive native valve endocarditis caused by Staphylococcus lugdunensis. Eur J Clin Microbiol Infect Dis 2005;24:149-152. https://doi.org/10.1007/s10096-005-1280-3
  11. Seenivasan MH, Yu VL. Staphylococcus lugdunensis endocarditis- the hidden peril of coagulase-negative staphylococcus in blood cultures. Eur J Clin Microbiol Infect Dis 2003;22:489-491. https://doi.org/10.1007/s10096-003-0953-z
  12. Arber N, Militianu A, Ben-Yehuda A, Krivoy N, Pinkhas J, Sidi Y. Native valve Staphylococcus epidermidis endocarditis: report of seven cases and review of the literature. Am J Med 1991;90:758-762. https://doi.org/10.1016/S0002-9343(05)80067-1
  13. Herchline TE, Barnishan J, Ayers LW, Fass RJ. Penicillinase production and in vitro susceptibilities of Staphylococcus lugdunensis. Antimicrob Agents Chemother 1990;34:2434-2435. https://doi.org/10.1128/AAC.34.12.2434
  14. Fleurette J, Bes M, Brun Y, et al. Clinical isolates of Staphylococcus lugdunensis and S. schleiferi: bacteriological characteristics and susceptibility to antimicrobial agents. Res Microbiol 1989;140:107-118. https://doi.org/10.1016/0923-2508(89)90044-2