Inflammatory Myofibroblastic Tumor of the Bladder: Report of Two Cases

방광의 염증성근섬유모세포종양: 증례 보고

  • Kim, Han-Na (Department of Radiology, The Catholic University of Korea) ;
  • Oh, Soon-Nam (Department of Radiology, The Catholic University of Korea) ;
  • Rha, Sung-Eun (Department of Radiology, The Catholic University of Korea) ;
  • Jung, Seung-Eun (Department of Radiology, The Catholic University of Korea) ;
  • Lee, Young-Joon (Department of Radiology, The Catholic University of Korea) ;
  • Byun, Jae-Young (Department of Radiology, The Catholic University of Korea) ;
  • Jung, Chan-Kwon (Departement of Hospital Pathology, The Catholic University of Korea) ;
  • Choi, Yeong-Jin (Departement of Hospital Pathology, The Catholic University of Korea)
  • 김한나 (가톨릭대학교 의과대학 방사선과학교실 서울성모병원 영상의학과) ;
  • 오순남 (가톨릭대학교 의과대학 방사선과학교실 서울성모병원 영상의학과) ;
  • 나성은 (가톨릭대학교 의과대학 방사선과학교실 서울성모병원 영상의학과) ;
  • 정승은 (가톨릭대학교 의과대학 방사선과학교실 서울성모병원 영상의학과) ;
  • 이영준 (가톨릭대학교 의과대학 방사선과학교실 서울성모병원 영상의학과) ;
  • 변재영 (가톨릭대학교 의과대학 방사선과학교실 서울성모병원 영상의학과) ;
  • 정찬권 (가톨릭대학교 의과대학 병리학교실 서울성모병원 병리과) ;
  • 최영진 (가톨릭대학교 의과대학 병리학교실 서울성모병원 병리과)
  • Received : 2009.11.09
  • Accepted : 2010.05.09
  • Published : 2010.09.01

Abstract

Inflammatory myofibroblastic tumor (IMT) is a rare condition of unknown origin. Pathologically, the lesion is composed of myofibroblastic spindle cells accompanied by an inflammatory infiltrate of plasma cells, lymphocytes, and eosinophils. We report two cases of inflammatory myofibroblastic tumor of the bladder which showed different imaging features and was falsely diagnosed as malignant tumors. We discuss the imaging findings along with a literature review.

염증성근섬유모세포종양은 원인이 밝혀지지 않은 드문 질환이다. 현재 병리학적으로 형질 세포, 림프구, 호산구 등의 염증성 침윤을 동반하는 근육섬유모세포로 이루어진 종양으로 정의된다. 저자들은 서로 다른 영상소견을 보이고 악성 종양으로 오인된 방광의 염증성근섬유모세포종양 2예의 영상 소견을 보고하며 문헌을 고찰하고자 한다.

Keywords

References

  1. Wong-You-Cheong JJ, Woodward PJ, Manning MA, Davis CJ. Inflammatory and non-neoplastic bladder masses: radiologic-pathologic correlation. Radiographics 2006;26:1847-1868 https://doi.org/10.1148/rg.266065126
  2. Kumar A, Bhatti SS, Sharma S, Gupta SD, Kumar R. Inflammatory pseudotumor of urinary bladder: a diagnostic and management dilemma. Int Urol Nephrol 2007;39:799-802 https://doi.org/10.1007/s11255-006-9113-6
  3. Narla LD, Newman B, Spottswood SS, Narla S, Kolli R. Inflammatory pseudotumor. Radiographics 2003;23:719-729 https://doi.org/10.1148/rg.233025073
  4. Mochizuki Y, Kanda S, Nomata K, Hayashi T, Yamasaki Y, Kanetake H, et al. Spontaneous regression of inflammatory pseudotumor of the urinary bladder. Urol Int 1999;63:255-257 https://doi.org/10.1159/000030463
  5. Kim SH, Cho JY, Kim SH. Inflammatory myofibroblastic pseudo-tumor of the urinary bladder in a patient with bilateral renal cell carcinoma. J Ultrasound Med 2008;27:483-486 https://doi.org/10.7863/jum.2008.27.3.483
  6. Park SB, Cho KS, Kim JK, Lee JH, Jeoung AK, Kwon WJ, et al. Inflammatory pseudotumor (myoblastic tumor) of genitourinary tract. AJR Am J Roentgenol 2008;191:1255-1262 https://doi.org/10.2214/AJR.07.3663
  7. Houben CH, Chan A, Lee KH, Tam YH, To KF, Cheung W, et al. Inflammatory myofibroblastic tumor of the bladder in children: what can be expected? Pediatr Surg Int 2007;23:815-819 https://doi.org/10.1007/s00383-007-1885-y
  8. Sugita R, Saito M, Miura M, Yuda F. Inflammatory pseudotumour of the bladder: CT and MRI findings. Br J Radiol 1999;72:809-811 https://doi.org/10.1259/bjr.72.860.10624350
  9. Young RH. Tumor-like lesions of the urinary bladder. Mod Pathol 2009;22 Suppl 2:S37-S52 https://doi.org/10.1038/modpathol.2008.201
  10. Ymamoto H, Yamaguchi H, Aishima S, Oda Y, Kohashi K, Oshiro Y, et al. Inflammatory myofibroblastic tumor versus IgG4-related sclerosing disease and inflammatory pseudotumor: a comparative clinicopathologic study. Am J Surg Pathol 2009;33:1330-1340 https://doi.org/10.1097/PAS.0b013e3181a5a207