Korean Journal of Radiology

The Korean Society of Radiology (대한영상의학회)
권호 표지
DOI QR코드

DOI QR Code

Ultrasonographic Features of Benign Adenomyoepithelioma of the Breast

  • Lee, Ji-Hye (Department of Radiology, Seoul St. Mary's Hospital, The Catholic University of Korea) ;
  • Kim, Sung-Hun (Department of Radiology, Seoul St. Mary's Hospital, The Catholic University of Korea) ;
  • Kang, Bong-Joo (Department of Radiology, Seoul St. Mary's Hospital, The Catholic University of Korea) ;
  • Lee, Ah-Won (Department of Pathology, Seoul St. Mary's Hospital, The Catholic University of Korea) ;
  • Song, Byung-Joo (Department of Surgery, Seoul St. Mary's Hospital, The Catholic University of Korea)
  • Received : 2010.05.12
  • Accepted : 2010.06.21
  • Published : 2010.10.01
⟨ Previous Next ⟩

Abstract

Objective: The purpose of this study was to evaluate the ultrasonographic features of benign adenomyoepithelioma of the breast. Materials and Methods: Between 2005 and 2009, five patients had histologically confirmed adenomyoepithelioma of the breast. We retrospectively evaluated the ultrasonographic findings of the tumors in correlation with the pathology, and reviewed medical records. Results: The clinical manifestations included a palpable mass in three patients, while mammographic screening helped detect abnormalities in two patients. Ultrasonograms showed masses with an oval (n = 3) or irregular (n = 2) shape, with uncircumscribed (n = 4) or relatively well-circumscribed (n = 1) margins, as well as with a hypoechoic (n = 3) or a complex echoic (n = 2) internal echo texture. Three patients had focal ductectasia adjacent to the mass. The ultrasonographic assessments were classified as Breast Imaging Reporting and Data System (BI-RADS) category 4A, with low suspicion of malignancy in two cases, and as category 4B, with intermediate suspicion of malignancy in three cases. The pathology revealed benign adenomyoepithelioma in all patients. Conclusion: Benign adenomyoepitheliomas appear as solid or complex echoic masses with suspicious malignant ultrasonographic features, which may be associated with adjacent ductectasia. Although adenomyoepithelioma is a rare breast tumor, awareness of its sonographic features will be helpful for the differential diagnosis from other tumors.

Keywords

References

  1. Hamperl H. The myothelia (myoepithelial cells). Normal state; regressive changes; hyperplasia; tumors. Curr Top Pathol 1970;53:161-220
  2. Rosen PP. Adenomyoepithelioma of the breast. Hum Pathol 1987;18:1232-1237 https://doi.org/10.1016/S0046-8177(87)80406-9
  3. Loose JH, Patchefsky AS, Hollander IJ, Lavin LS, Cooper HS, Katz SM. Adenomyoepithelioma of the breast. A spectrum of biologic behavior. Am J Surg Pathol 1992;16:868-876 https://doi.org/10.1097/00000478-199209000-00005
  4. Tavassoli FA. Myoepithelial lesions of the breast. Myoepitheliosis, adenomyoepithelioma, and myoepithelial carcinoma. Am J Surg Pathol 1991;15:554-568 https://doi.org/10.1097/00000478-199106000-00004
  5. Howlett DC, Mason CH, Biswas S, Sangle PD, Rubin G, Allan SM. Adenomyoepithelioma of the breast: spectrum of disease with associated imaging and pathology. AJR Am J Roentgenol 2003;180:799-803 https://doi.org/10.2214/ajr.180.3.1800799
  6. Fan F, Smith W, Wang X, Jewell W, Thomas PA, Tawfik O. Myoepithelial carcinoma of the breast arising in an adenomyoepithelioma: mammographic, ultrasound and histologic features. Breast J 2007;13:203-204 https://doi.org/10.1111/j.1524-4741.2007.00403.x
  7. Felipo F, Del Agua C, Eguizabal C, Vaquero M. Benign adenomyoepithelioma of the breast: a case with gross mimicking of malignancy. Breast J 2002;8:383-384 https://doi.org/10.1046/j.1524-4741.2002.08610.x
  8. Tukel S, Ustuner E, Aytac SK. Adenomyoepithelioma of the breast. J Ultrasound Med 2001;20:1021-1024
  9. Ruiz-Delgado ML, Lopez-Ruiz JA, Eizaguirre B, Saiz A, Astigarraga E, Fernandez-Temprano Z. Benign adenomyoepithelioma of the breast: imaging findings mimicking malignancy and histopathological features. Acta Radiol 2007;48:27-29 https://doi.org/10.1080/02841850601080432
  10. Ahmed AA, Heller DS. Malignant adenomyoepithelioma of the breast with malignant proliferation of epithelial and myoepithelial elements: a case report and review of the literature. Arch Pathol Lab Med 2000;124:632-636
  11. Lee WY. Fine needle aspiration cytology of adenomyoepithelioma of the breast: a case indistinguishable from phyllodes tumor in cytologic findings and clinical behavior. Acta Cytol 2000;44:488-490
  12. Hikino H, Kodama K, Yasui K, Ozaki N, Nagaoka S, Miura H. Intracystic adenomyoepithelioma of the breast--case report and review. Breast Cancer 2007;14:429-433 https://doi.org/10.2325/jbcs.14.429
  13. Papaevangelou A, Pougouras I, Liapi G, Pierrakakis S, Tibishrani M, Setakis N. Cystic adenomyoepithelioma of the breast. Breast 2004;13:356-358 https://doi.org/10.1016/j.breast.2003.11.006
  14. Noel JC, Simon P, Aguilar SF. Malignant myoepithelioma arising in cystic adenomyoepithelioma. Breast J 2006;12:386 https://doi.org/10.1111/j.1075-122X.2006.00286.x

Cited by

  1. Imaging features of benign adenomyoepithelioma of the breast vol.41, pp.4, 2013, https://doi.org/10.1002/jcu.22036
  2. Adenomyoepithelioma with Ductal Carcinoma In Situ: A Case Report and Review of the Literature vol.2013, pp.None, 2010, https://doi.org/10.1155/2013/521417
  3. Adenomyoepithelioma of the Breast with Hemorrhagic Change Diagnosed as Papilloma on Core Needle Biopsy: A Case Report vol.75, pp.5, 2016, https://doi.org/10.3348/jksr.2016.75.5.394
  4. A Case of Adenomyoepithelioma of the Breast Showing Strong Uptake of 18F‐Fluorodeoxyglucose on a Positron Emission Tomography vol.23, pp.2, 2017, https://doi.org/10.1111/tbj.12715
  5. Challenges in management of male breast adenomioepithelioma with malignant behavior : Case report vol.98, pp.43, 2010, https://doi.org/10.1097/md.0000000000017587
  6. Adenomyoepithelioma of the Breast: Which Mimicking Malignancy on Ultrasound Elastography vol.25, pp.1, 2010, https://doi.org/10.15746/sms.19.009
  7. Rapid Local Recurrence of Breast Myoepithelial Carcinoma Arising in Adenomyoepithelioma: A Case Report vol.81, pp.1, 2020, https://doi.org/10.3348/jksr.2020.81.1.207
  8. Adenomyoepithelioma of the breast with prominent cystic changes: a case report vol.21, pp.1, 2010, https://doi.org/10.1186/s12905-021-01432-z