Clinical Endoscopy

The Korean Society of Gastrointestinal Endoscopy (대한소화기내시경학회)
권호 표지

Simultaneous Melanosis Duodeni and Melanosis Ilei in a Patient Taking Oral Iron

경구철분제제 투여 중 동시에 발견된 십이지장 및 회장 흑색소증 1예

  • Lee, Kyoung-Won (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Jeong, Woo-Jin (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Lee, Joung-Hwa (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Kang, Jong-Won (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Jang, Kyeong-Hee (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Han, Koon-Hee (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Kang, Gil-Hyun (Department of Pathology, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Cheon, Gab-Jin (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine)
  • 이경원 (울산대학교 의과대학 강릉아산병원 소화기내과학교실) ;
  • 정우진 (울산대학교 의과대학 강릉아산병원 소화기내과학교실) ;
  • 이정화 (울산대학교 의과대학 강릉아산병원 소화기내과학교실) ;
  • 강종원 (울산대학교 의과대학 강릉아산병원 소화기내과학교실) ;
  • 장경희 (울산대학교 의과대학 강릉아산병원 소화기내과학교실) ;
  • 한군희 (울산대학교 의과대학 강릉아산병원 소화기내과학교실) ;
  • 강길현 (울산대학교 의과대학 강릉아산병원 진단병리학교실) ;
  • 천갑진 (울산대학교 의과대학 강릉아산병원 소화기내과학교실)
  • Received : 2010.06.08
  • Accepted : 2010.09.02
  • Published : 2010.11.30
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Abstract

Melanosis means the accumulation of brown or black pigment in an organ. Melanosis can be observed in virtually all parts of the gastrointestinal tract. However, it most frequently affects the colon. It is said that melanosis in small intestine is very rare, and no case has been reported in which melanosis was simultaneously noted in duodenum and ileum without involving the colonic mucosa. Here we report a case of melanosis duodeni and melanosis ilei which were found simultaneously in a 56-year-old female patient with chronic renal failure and heart failure who had been taking oral ferrous sulfate for 3 years.

위장관의 흑색소증은 점막이 비정상적으로 어두운 색의 착색이 된 상태를 말하며 대부분 대장에서 관찰된다. 소장의 흑색소증은 매우 드물며, 고혈압, 만성신부전, 당뇨병, 위장관 출혈, 엽산 부족, 심부전 그리고 빈혈 등의 기저질환을 가지고 있는 환자에서 항고혈압제, 이뇨제, 경구 철분제제, 그리고 경구 활성탄의 사용과 연관되어 발생할 수 있다. 대장 점막의 침범 없이 십이지장과 회장에서 동시에 흑색소증이 확인된 예는 현재까지 보고된 바가 없다. 저자들은 만성신부전, 심부전을 가진 56세 여자 환자에서 약 3년간의 경구 철분제제 복용 중 대장점막의 침범 없이 동시에 발견된 십이지장과 회장의 흑색소증 1예를 경험하여 문헌고찰과 함께 보고한다.

Keywords

References

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