색소 내시경 중 루골 용액에 의하여 발생한 급성 위 점막 손상 1예

Acute Gastric Mucosal Injury Induced by Lugol's Solution During Chromoendoscopy

  • 나희경 (울산대학교 의과대학 서울아산병원 내과학교실) ;
  • 김도훈 (울산대학교 의과대학 서울아산병원 내과학교실) ;
  • 임현 (울산대학교 의과대학 서울아산병원 내과학교실) ;
  • 권오성 (울산대학교 의과대학 서울아산병원 내과학교실) ;
  • 최기돈 (울산대학교 의과대학 서울아산병원 내과학교실) ;
  • 이진혁 (울산대학교 의과대학 서울아산병원 내과학교실) ;
  • 정훈용 (울산대학교 의과대학 서울아산병원 내과학교실) ;
  • 김진호 (울산대학교 의과대학 서울아산병원 내과학교실)
  • Na, Hee-Kyong (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Do-Hoon (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lim, Hyun (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kwon, O-Sung (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Choi, Kee-Don (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Gin-Hyug (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Jung, Hwoon-Yong (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Kim, Jin-Ho (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine)
  • 투고 : 2010.06.18
  • 심사 : 2010.09.08
  • 발행 : 2010.10.30

초록

색소내시경시 사용되는 루골 용액은 비교적 안전하다고 알려진 염색액이나 드물게 흉통, 구토, 심와부 및 상복부 통증을 일으키고 식도 및 위 점막 손상을 일으키는 증례가 보고되었다. 저자들은 루골 용액을 이용한 색소내시경 이후 발생한 출혈성 위 점막 손상을 1예 경험하여 보고하는 바이다. 이러한 부작용을 잘 숙지하여 상부 위장관 내시경 시행시 발생할 수 있는 루골 용액과 관련된 위 점막 손상을 오진하는 일이 없어야겠다. 낮은 농도의 요오드가 포함된 루골 용액을 사용하고 색소내시경 시행 후 가급적 빨리 위 내로 저류된 루골 용액을 흡인한다면 이러한 부작용을 최소화 할 수 있을 것으로 생각된다.

Chromoendoscopy using Lugol's iodine solution is widely used to improve the detection of esophageal dysplasia or early squamous carcinoma. Although the solution helps to notice esophageal lesions and to delineate the lesions more clearly, it can cause mucosal irritation leading to retrosternal pain and epigastric discomfort infrequently. We report a case of acute gastric mucosal injury after application of Lugol's solution during chromoendoscopy in a 63-year-old woman.

키워드

참고문헌

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