The Korean journal of internal medicine

  • 제25권3호
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  • Pages.288-293
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  • 2010
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  • 1226-3303(pISSN)
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  • 2005-6648(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
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Changing Donor Source Pattern for Kidney Transplantation over 40 Years: A Single-Center Experience

  • Chung, Byung-Ha (Organ Transplantation Center, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Jung, Mi-Hyang (Organ Transplantation Center, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Bae, Sung-Ha (Organ Transplantation Center, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Kang, Suk-Hui (Organ Transplantation Center, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Hwang, Hyeon-Seok (Organ Transplantation Center, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Hyoung, Bok-Jin (Organ Transplantation Center, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Lee, So-Young (Organ Transplantation Center, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Jeon, Youn-Ju (Organ Transplantation Center, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Choi, Bum-Soon (Organ Transplantation Center, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Park, Cheol-Whee (Organ Transplantation Center, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Kim, Yong-Soo (Organ Transplantation Center, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Kim, Ji-Il (Organ Transplantation Center, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Moon, In-Sung (Organ Transplantation Center, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Yang, Chul-Woo (Organ Transplantation Center, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine)
  • 투고 : 2010.01.24
  • 심사 : 2010.03.22
  • 발행 : 2010.09.01
⟨ 이전 논문 다음 논문 ⟩

초록

Background/Aims: Kidney transplantations at our center rely mainly on living donors. The purpose of this study was to suggest future donor supply directions by reviewing changing trends in donor type. Methods: During the past 40 years, 1,690 kidney transplantations were performed at our center. We divided the follow-up period into four decades and the donor population into three groups: living related, living unrelated, and deceased. We analyzed changing trends in donors from each group for each decade. Patients receiving overseas transplantation were also included. Results: The proportion of living related donors decreased from 84% (54/64) in the 1970s to 61% (281/458) in the 2000s. Living unrelated donors showed a sustained proportion of around 20% after 1990. However, among living unrelated donors, the proportion of spouse donors increased from 4.6% (17/369) in the 1980s to 8.5% (39/458) in the 2000s. Transplants from deceased donors were only 3.3% (12/369) in the 1980s. However the proportion of deceased donors increased gradually, reaching 13.2% (105/799) in the 1990s and 19.9% (91/458) after 2000. Overseas transplantations increased after 2000 and reached 20% of all cases treated in our center during the 2000s. Such transplantations peaked in 2006 and decreased markedly thereafter. Conclusions: The proportion of each donor type has continuously changed, and the changes were associated with changes in the social structure and system. We expect that this study could be an important reference for other countries to estimate future changes of donor type.

키워드

참고문헌

  1. Satayathum S, Pisoni RL, McCullough KP, et al. Kidney transplantation and wait-listing rates from the international Dialysis Outcomes and Practice Patterns Study (DOPPS). Kidney Int 2005;68:330-337. https://doi.org/10.1111/j.1523-1755.2005.00412.x
  2. Sheehy E, Conrad SL, Brigham LE, et al. Estimating the number of potential organ donors in the United States. N Engl J Med 2003;349:667-674. https://doi.org/10.1056/NEJMsa021271
  3. Baid-Agrawal S, Frei UA. Living donor renal transplantation: recent developments and perspectives. Nat Clin Pract Nephrol 2007;3:31-41. https://doi.org/10.1038/ncpneph0383
  4. Kauffman HM, Cherikh WS, McBride MA, Cheng Y, Hanto DW. Post-transplant de novo malignancies in renal transplant recipients: the past and present. Transpl Int 2006;19:607-620. https://doi.org/10.1111/j.1432-2277.2006.00330.x
  5. Ichimaru N, Takahara S. Japan's experience with living-donor kidney transplantation across ABO barriers. Nat Clin Pract Nephrol 2008;4:682-692. https://doi.org/10.1038/ncpneph0967
  6. ESRD Registry Committee Korean Society of Nephrology. Current Renal Replacement Therapy in Korea, Insan Memorial Dialysis Registry 2007 [Internet]. Seoul: The Korean Society of Nephrology; [cited 2010 Jan 01]. Available from: http://www. ksn.or.kr.
  7. Statistics Korea. Korean Statistical Information Service: Summary of census household [Internet]. Daejeon: Statistics Korea; c2010 [cited 2010 Jan 01]. Available from: http://www. kosis.kr.
  8. Ahmad N, Ahmed K, Khan MS, et al. Living-unrelated donor renal transplantation: an alternative to living-related donor transplantation? Ann R Coll Surg Engl 2008;90:247-250. https://doi.org/10.1308/003588408X261636
  9. Roozbeh J, Mehdizadeh AR, Izadfar MA, Razmkon A, Salahi H, Malek-Hosseini SA. Comparison of spousal with other donor groups: study of a single center. Transplant Proc 2006;38:562-563. https://doi.org/10.1016/j.transproceed.2005.12.058
  10. Sakai K, Okamoto M, Suzuki T, et al. The excellent results of spousal kidney transplantation: experience in a Japanese single center. Transplant Proc 2008;40:2118-2120. https://doi.org/10.1016/j.transproceed.2008.07.072
  11. Yoon HE, Song JC, Hyoung BJ, et al. Comparison of long-term outcomes between spousal transplants and other living unrelated donor transplants: single-center experience. Nephron Clin Pract 2009;113:c241-c249. https://doi.org/10.1159/000235248
  12. Bollinger RR, Cho WH. Organ allocation for transplantation in the USA and Korea: the changing roles of equity and utility. Yonsei Med J 2004;45:1035-1042.
  13. Korean Network for Organ Sharing. 2008 KONOS Annual Report [Internet]. Seoul: Korean Network for Organ Sharing; 2009 [cited 2010 Jun 20]. Available from: http://www.konos.go.kr.
  14. Budiani-Saberi DA, Delmonico FL. Organ trafficking and transplant tourism: a commentary on the global realities. Am J Transplant 2008;8:925-929. https://doi.org/10.1111/j.1600-6143.2008.02200.x

피인용 문헌

  1. Long-Term Risk of Hypertension and Chronic Kidney Disease in Living Kidney Donors vol.44, pp.3, 2012, https://doi.org/10.1016/j.transproceed.2011.12.066
  2. Clinical Outcomes between Living Related and Living Unrelated Kidney Transplantation in ABO-Incompatible Kidney Transplant Recipients vol.87, pp.6, 2014, https://doi.org/10.3904/kjm.2014.87.6.698
  3. Risk factors in the progression of BK virus-associated nephropathy in renal transplant recipients vol.30, pp.6, 2010, https://doi.org/10.3904/kjim.2015.30.6.865
  4. Immunologic and non-immunologic complications of a third kidney transplantation vol.30, pp.5, 2010, https://doi.org/10.3904/kjim.2015.30.5.657
  5. Comparison of clinical outcomes between ABO-compatible and ABO-incompatible spousal donor kidney transplantation vol.35, pp.1, 2010, https://doi.org/10.1016/j.krcp.2015.11.001
  6. Impact of ABO incompatible kidney transplantation on living donor transplantation vol.12, pp.3, 2010, https://doi.org/10.1371/journal.pone.0173878
  7. Experience with Pediatric Kidney Transplantation, 1985-2016: A Single Regional Center Study vol.21, pp.2, 2017, https://doi.org/10.3339/jkspn.2017.21.2.69
  8. Solitary kidney and risk of chronic kidney disease vol.34, pp.9, 2010, https://doi.org/10.1007/s10654-019-00520-7
  9. Expanding the Non-Invasive Diagnosis of Acute Rejection in Kidney Transplants Through Detection of Donor-Derived DNA in Urine: Proof-of-Concept Study vol.41, pp.5, 2010, https://doi.org/10.3343/alm.2021.41.5.469