The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
권호 표지

A case of syndrome of inappropriate secretion of antidiuretic hormone associated with paroxetine

Paroxetine 복용 후 발생한 항이뇨호르몬 분비이상 증후군 1예

  • Ahn, Hyo-Jun (Department of Internal Medicine, The Catholic University of Korea School of Medicine) ;
  • Kim, Hyung-Wook (Department of Internal Medicine, The Catholic University of Korea School of Medicine) ;
  • Kim, Young-Soo (Department of Internal Medicine, The Catholic University of Korea School of Medicine) ;
  • Kim, Young-Ok (Department of Internal Medicine, The Catholic University of Korea School of Medicine) ;
  • Yoon, Sun-Ae (Department of Internal Medicine, The Catholic University of Korea School of Medicine) ;
  • Choi, Jae-Ki (Department of Internal Medicine, The Catholic University of Korea School of Medicine)
  • 안효준 (가톨릭대학교 의학전문대학원 내과학교실) ;
  • 김형욱 (가톨릭대학교 의학전문대학원 내과학교실) ;
  • 김영수 (가톨릭대학교 의학전문대학원 내과학교실) ;
  • 김영옥 (가톨릭대학교 의학전문대학원 내과학교실) ;
  • 윤선애 (가톨릭대학교 의학전문대학원 내과학교실) ;
  • 최재기 (가톨릭대학교 의학전문대학원 내과학교실)
  • Received : 2009.12.09
  • Accepted : 2010.01.05
  • Published : 2010.12.01
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Abstract

Paroxetine is a well-known selective serotonin reuptake inhibitor, and has been reported to be advantageous for chronic pain control. Paroxetine is increasingly used for various types of chronic pain because of its safety; however, hyponatremia, or syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with paroxetine, has been reported. This complication is relatively rare, but some patients have presented with severe neurological symptoms. Here, we report the first case of SIADH associated with paroxetine in Korea.

저자들은 우울증으로 paroxetine을 투여받은 후 전신 쇠약감과 저나트륨혈증이 발생한 환자에서 SIADH를 진단한 증례를 경험하여 국내 최초로 보고하는 바이다.

Keywords

References

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