The reasons for the increased incidence of colorectal cancer in Korea

최근에 한국인에서 대장암이 증가하는 이유는?

  • Koh, Seong-Joon (Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine) ;
  • Kim, Joo-Sung (Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine)
  • 고성준 (서울대학교 의과대학 내과학교실, 간연구소) ;
  • 김주성 (서울대학교 의과대학 내과학교실, 간연구소)
  • Published : 2010.08.01

Abstract

The incidence of colorectal cancer in Korea has increased dramatically over the past few decades. According to the National Cancer Registry, the age-standardized incidence rates increased from 27.1 to 44.5 per 100,000 for men and from 17.2 to 24.3 per 100,000 for women between 1999 and 2007. The overall incidence of colorectal cancer increased by 7.0% annually in men and 5.3% in women from 1999 to 2007, while the incidence rates of the most common cancers, such as stomach and liver cancers, decreased during the same period. Epidemiologic studies have suggested that higher intakes of red and processed meat, a lack of physical activity, obesity, and alcohol drinking are risk factors for colorectal cancer. During the past few decades, significant socio-economic changes have taken place in Korea with respect to the economy, industrial structure, dietary habits, physical activity, and prevalence of obesity. Changes in dietary habits and lifestyle-related factors are believed to be the reasons for the increase in the incidence of colorectal cancer in Korea.

Keywords

References

  1. Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin 55:74-108, 2005 https://doi.org/10.3322/canjclin.55.2.74
  2. Ferlay J, Bray F, Pisani P, Parkin D. GLOBOCAN 2002: cancer incidence, mortality and prevalence worldwide. IARC cancerbase No.5, Version 2.0 Lyon, IARC press, 2004
  3. Chan AT, Giovannucci EL. Primary prevention of colorectal cancer. Gastroenterology 138:2029-2043, 2010 https://doi.org/10.1053/j.gastro.2010.01.057
  4. Yiu HY, Whittemore AS, Shibata A. Increasing colorectal cancer incidence rates in Japan. Int J Cancer 109:777-781, 2004 https://doi.org/10.1002/ijc.20030
  5. Sung JJ, Lau JY, Goh KL, Leung WK. Increasing incidence of colorectal cancer in Asia: implications for screening. Lancet Oncol 6:871-876, 2005 https://doi.org/10.1016/S1470-2045(05)70422-8
  6. 김진희, 함명일, 박은철, 박재현, 박종혁, 김성은, 김성경, 임진 화, 최귀선. 2005 년 암의 경제적 비용부담 추계. 예방의학회지 42:190-198, 2009 https://doi.org/10.3961/jpmph.2009.42.3.190
  7. 중앙암등록본부. 2006-2007년 암발생률, 1993-2007년 암발생 자의 암생존율, 2007년 암유병률 통계. 2009
  8. Shimoda T, Ikegami M, Fujisaki J, Matsui T, Aizawa S, Ishikawa E. Early colorectal carcinoma with special reference to its development de novo. Cancer 64:1138-1146, 1989 https://doi.org/10.1002/1097-0142(19890901)64:5<1138::AID-CNCR2820640529>3.0.CO;2-A
  9. Kuramoto S, Oohara T. Flat early cancers of the large intestine. Cancer 64:950-955, 1989 https://doi.org/10.1002/1097-0142(19890815)64:4<950::AID-CNCR2820640430>3.0.CO;2-O
  10. 김도영, 김원호, 강진경, 박인서, 최홍재, 노성훈, 민진식. 조기 대장암의 임상적 고찰. 대한소화기학회지 25:295-304, 1993
  11. 김흥업, 김영호, 송상용, 정정환, 김종형, 김경희, 심상군, 손희 정, 이풍렬, 김재준, 이종철. 한국인에서 조기대장암의 형태적 특성. 대한소화기내시경학회지 29:126-132, 2004
  12. Goto H, Oda Y, Murakami Y, Tanaka T, Hasuda K, Goto S, Sasaki Y, Sakisaka S, Hattori M. Proportion of de novo cancers among colorectal cancers in Japan. Gastroenterology 131:40-46, 2006 https://doi.org/10.1053/j.gastro.2006.04.010
  13. Chen CD, Yen MF, Wang WM, Wong JM, Chen TH. A case-cohort study for the disease natural history of adenoma-carcinoma and de novo carcinoma and surveillance of colon and rectum after polypectomy: implication for efficacy of colonoscopy. Br J Cancer 88:1866-1873, 2003 https://doi.org/10.1038/sj.bjc.6601007
  14. World Cancer Research Fund/American Institute for Cancer Research. Food, Nutrition, Physical Activity, and the Prevention of Cancer: a Global Perspective. Washington DC: AICR, 2007
  15. Maskarinec G, Noh JJ. The effect of migration on cancer incidence among Japanese in Hawaii. Ethn Dis 14:431-439, 2004
  16. Iwasaki M, Mameri CP, Hamada GS, Tsugane S. Cancer mortality among Japanese immigrants and their descendants in the state of Sao Paulo, Brazil, 1999-2001. Jpn J Clin Oncol 34:673-680, 2004 https://doi.org/10.1093/jjco/hyh123
  17. Lee J, Demissie K, Lu SE, Rhoads GG. Cancer incidence among Korean-American immigrants in the United States and native Koreans in South Korea. Cancer Control 14:78-85, 2007
  18. Armstrong B, Doll R. Environmental factors and cancer incidence and mortality in different countries, with special reference to dietary practices. Int J Cancer 15:617-631, 1975 https://doi.org/10.1002/ijc.2910150411
  19. Parkin DM, Olsen AH, Sasieni P. The potential for prevention of colorectal cancer in the UK. Eur J Cancer Prev 18:179-190, 2009 https://doi.org/10.1097/CEJ.0b013e32830c8d83
  20. Giovannucci E, Rimm EB, Stampfer MJ, Colditz GA, Ascherio A, Willett WC. Intake of fat, meat, and fiber in relation to risk of colon cancer in men. Cancer Res 54:2390-2397, 1994
  21. Key TJ, Fraser GE, Thorogood M, Appleby PN, Beral V, Reeves G, Burr ML, Chang-Claude J, Frentzel-Beyme R, Kuzma JW, Mann J, McPherson K. Mortality in vegetarians and non-vegetarians: a collaborative analysis of 8300 deaths among 76,000 men and women in five prospective studies. Public Health Nutr 1:33-41, 1998
  22. Fraser GE. Diet as primordial prevention in Seventh-Day Adventists. Prev Med 29:S18-S23, 1999 https://doi.org/10.1006/pmed.1998.0415
  23. Larsson SC, Wolk A. Meat consumption and risk of colorectal cancer: a meta-analysis of prospective studies. Int J Cancer 119:2657-2664, 2006 https://doi.org/10.1002/ijc.22170
  24. Cross AJ, Ferrucci LM, Risch A, Graubard BI, Ward MH, Park Y, Hollenbeck AR, Schatzkin A, Sinha R. A large prospective study of meat consumption and colorectal cancer risk: an investigation of potential mechanisms underlying this association. Cancer Res 70:2406-2414, 2010 https://doi.org/10.1158/0008-5472.CAN-09-3929
  25. Willett WC, Stampfer MJ, Colditz GA, Rosner BA, Speizer FE. Relation of meat, fat, and fiber intake to the risk of colon cancer in a prospective study among women. N Engl J Med 323:1664-1672, 1990 https://doi.org/10.1056/NEJM199012133232404
  26. Birt DF. The influence of dietary fat on carcinogenesis: lessons from experimental models. Nutr Rev 48:1-5, 1990
  27. Fung T, Hu FB, Fuchs C, Giovannucci E, Hunter DJ, Stampfer MJ, Colditz GA, Willett WC. Major dietary patterns and the risk of colorectal cancer in women. Arch Intern Med 163:309-314, 2003 https://doi.org/10.1001/archinte.163.3.309
  28. Levi F, Pasche C, Lucchini F, La Vecchia C. Dietary fibre and the risk of colorectal cancer. Eur J Cancer 37:2091-2096, 2001 https://doi.org/10.1016/S0959-8049(01)00254-4
  29. Trock B, Lanza E, Greenwald P. Dietary fiber, vegetables, and colon cancer: critical review and meta-analyses of the epidemiologic evidence. J Natl Cancer Inst 82:650-661, 1990 https://doi.org/10.1093/jnci/82.8.650
  30. Giovannucci E, Willett WC. Dietary factors and risk of colon cancer. Ann Med 26:443-452, 1994 https://doi.org/10.3109/07853899409148367
  31. Kim S, Moon S, Popkin BM. The nutrition transition in South Korea. Am J Clin Nutr 71:44-53, 2000
  32. Lee SI, Moon HY, Kwak JM, Kim J, Min BW, Um JW, Kim SH. Relationship between meat and cereal consumption and colorectal cancer in Korea and Japan. J Gastroenterol Hepatol 23:138-140, 2008
  33. 오세영, 이지현, 김효종. 식이유형과 대장암 위험도와의 관련성 분석. 대한영양학회지 37:550-556, 2004
  34. Boyle P, Zaridze DG, Smans M. Descriptive epidemiology of colorectal cancer. Int J Cancer 36:9-18, 1985 https://doi.org/10.1002/ijc.2910360103
  35. Tavani A, Braga C, La Vecchia C, Conti E, Filiberti R, Montella M, Amadori D, Russo A, Franceschi S. Physical activity and risk of cancers of the colon and rectum: an Italian case-control study. Br J Cancer 79:1912-1916, 1999 https://doi.org/10.1038/sj.bjc.6690304
  36. Markowitz S, Morabia A, Garibaldi K, Wynder E. Effect of occupational and recreational activity on the risk of colorectal cancer among males: a case-control study. Int J Epidemiol 21:1057-1062, 1992 https://doi.org/10.1093/ije/21.6.1057
  37. Giovannucci E, Ascherio A, Rimm EB, Colditz GA, Stampfer MJ, Willett WC. Physical activity, obesity, and risk for colon cancer and adenoma in men. Ann Intern Med 122:327-334, 1995 https://doi.org/10.7326/0003-4819-122-5-199503010-00002
  38. Giovannucci E, Colditz GA, Stampfer MJ, Willett WC. Physical activity, obesity, and risk of colorectal adenoma in women (United States). Cancer Causes Control 7:253-263, 1996 https://doi.org/10.1007/BF00051301
  39. Wolin KY, Yan Y, Colditz GA, Lee IM. Physical activity and colon cancer prevention: a meta-analysis. Br J Cancer 100:611-616, 2009 https://doi.org/10.1038/sj.bjc.6604917
  40. Severson RK, Nomura AM, Grove JS, Stemmermann GN. A prospective analysis of physical activity and cancer. Am J Epidemiol 130:522-529, 1989
  41. Thune I, Lund E. Physical activity and risk of colorectal cancer in men and women. Br J Cancer 73:1134-1140, 1996 https://doi.org/10.1038/bjc.1996.218
  42. 김동현, 안윤옥, 이봉화, 황대용, 이훈재. 육체적 활동수준과 대장암 발생위험에 관한 환자-대조군 연구. 대한암예방학회지 7:116-126, 2002
  43. Wolin KY, Lee IM, Colditz GA, Glynn RJ, Fuchs C, Giovannucci E. Leisure-time physical activity patterns and risk of colon cancer in women. Int J Cancer 121:2776-2781, 2007 https://doi.org/10.1002/ijc.23009
  44. Schwartz JB, Akin JS, Popkin BM. Price and income elasticities of demand for modern health care: the case of infant delivery in the Philippines. World Bank Econ Rev 2:49-76, 1988 https://doi.org/10.1093/wber/2.1.49
  45. Harvey RJ, Fletcher J, French DJ. Social reasoning: a source of influence on aggression. Clin Psychol Rev 21:447-469, 2001 https://doi.org/10.1016/S0272-7358(99)00068-9
  46. Hill JO, Peters JC. Environmental contributions to the obesity epidemic. Science 280:1371-1374, 1998 https://doi.org/10.1126/science.280.5368.1371
  47. Choi YJ, Cho YM, Park CK, Jang HC, Park KS, Kim SY, Lee HK Rapidly increasing diabetes-related mortality with socio-environmental changes in South Korea during the last two decades. Diabetes Res Clin Pract 74:295-300, 2006 https://doi.org/10.1016/j.diabres.2006.03.029
  48. Lee SK, Sobal J. Socio-economic, dietary, activity, nutrition and body weight transitions in South Korea. Public Health Nutr 6:665-674, 2003
  49. Giovannucci E. Insulin and colon cancer. Cancer Causes Control 6:164-179, 1995 https://doi.org/10.1007/BF00052777
  50. Otani T, Iwasaki M, Ishihara J, Sasazuki S, Inoue M, Tsugane S. Dietary fiber intake and subsequent risk of colorectal cancer: the Japan Public Health Center-based prospective study. Int J Cancer 119:1475-1480, 2006 https://doi.org/10.1002/ijc.22007
  51. MacInnis RJ, English DR, Haydon AM, Hopper JL, Gertig DM, Giles GG. Body size and composition and risk of rectal cancer (Australia). Cancer Causes Control 17:1291-1297, 2006 https://doi.org/10.1007/s10552-006-0074-y
  52. Tamakoshi K, Wakai K, Kojima M, Watanabe Y, Hayakawa N, Toyoshima H, Yatsuya H, Kondo T, Tokudome S, Hashimoto S, Suzuki K, Ito Y, Tamakoshi A. A prospective study of body size and colon cancer mortality in Japan: The JACC Study. Int J Obes Relat Metab Disord 28:551-558, 2004 https://doi.org/10.1038/sj.ijo.0802603
  53. Ning Y, Wang L, Giovannucci EL. A quantitative analysis of body mass index and colorectal cancer: findings from 56 observational studies. Obes Rev 2009 [Epub ahead of print]
  54. Oh SW, Yoon YS, Shin SA. Effects of excess weight on cancer incidences depending on cancer sites and histologic findings among men: Korea National Health Insurance Corporation Study. J Clin Oncol 23:4742-4754, 2005 https://doi.org/10.1200/JCO.2005.11.726
  55. Song YM, Sung J, Ha M. Obesity and risk of cancer in postmenopausal Korean women. J Clin Oncol 26:3395-3402, 2008 https://doi.org/10.1200/JCO.2007.15.7867
  56. Otake S, Takeda H, Suzuki Y, Fukui T, Watanabe S, Ishihama K, Saito T, Togashi H, Nakamura T, Matsuzawa Y, Kawata S. Association of visceral fat accumulation and plasma adiponectin with colorectal adenoma: evidence for participation of insulin resistance. Clin Cancer Res 11:3642-3646, 2005 https://doi.org/10.1158/1078-0432.CCR-04-1868
  57. Kang HW, Kim D, Kim HJ, Kim CH, Kim YS, Park MJ, Kim JS, Cho SH, Sung MW, Jung HC, Lee HS, Song IS. Visceral obesity and insulin resistance as risk factors for colorectal adenoma: a cross-sectional, case-control study. Am J Gastroenterol 105:178-187, 2010 https://doi.org/10.1038/ajg.2009.541
  58. KwonJW, Song YM, Sung J, Sohn Y, Cho SI. Varying patterns of BMI increase in sex and birth cohorts of Korean adults. Obesity (Silver Spring) 15:277-282, 2007 https://doi.org/10.1038/oby.2007.539