The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
권호 표지

Autologous peripheral blood stem cell transplantation with high-dose therapy for anaplastic large cell lymphoma with progressive myelofibrosis

진행성 골수섬유화증을 동반한 역형성 대세포 림프종 환자에게 시행된 자가 말초혈액 조혈모세포 이식 1예

  • Lee, Na-Ri (Division of Hematology/Oncology and Internal Medicine, Chonbuk National University Medical School) ;
  • Song, Eun-Kee (Division of Hematology/Oncology and Internal Medicine, Chonbuk National University Medical School) ;
  • Yhim, Ho-Young (Division of Hematology/Oncology and Internal Medicine, Chonbuk National University Medical School) ;
  • Jang, Kyu-Yun (Division of Pathology, Chonbuk National University Medical School) ;
  • Choi, Sam-Im (Division of Laboratory Medicine, Chonbuk National University Medical School) ;
  • Yim, Chang-Yeol (Division of Hematology/Oncology and Internal Medicine, Chonbuk National University Medical School) ;
  • Kwak, Jae-Yong (Division of Hematology/Oncology and Internal Medicine, Chonbuk National University Medical School)
  • 이나리 (전북대학교 의과대학 내과학교실 혈액종양내과) ;
  • 송은기 (전북대학교 의과대학 내과학교실 혈액종양내과) ;
  • 임호영 (전북대학교 의과대학 내과학교실 혈액종양내과) ;
  • 장규윤 (전북대학교 의과대학 병리학교실) ;
  • 최삼임 (전북대학교 의과대학 진단검사학과교실) ;
  • 임창열 (전북대학교 의과대학 내과학교실 혈액종양내과) ;
  • 곽재용 (전북대학교 의과대학 내과학교실 혈액종양내과)
  • Received : 2009.12.11
  • Accepted : 2010.02.25
  • Published : 2010.07.01
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Abstract

Myelofibrosis is a myeloproliferative neoplasm characterized by abnormal bone marrow megakaryocyte proliferation with reticulin and collagen fibrosis, leukoerythroblastosis, anemia, increased level of serum lactate dehydrogenase and splenomegaly. Myelofibrosis associated with malignant lymphoma is rare and survival rates appear to have been poor. Herein, we describe our experience in a patient who remained in complete remission with high-dose therapy (HDT) with autologous peripheral blood stem cell transplantation (PBSCT) for ALK-negative ALCL presenting with rapidly progressing myelofibrosis.

Keywords

References

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