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흑삼을 함유한 한방소재 화장품의 주름개선 효과

Anti-wrinkle Effect of Oriental Medicine Cosmetics Containing Black Ginseng

  • 투고 : 2010.07.13
  • 심사 : 2010.09.08
  • 발행 : 2010.09.30

초록

맥문동, 차가버섯, 감초, 보기보혈(백출, 백복령, 당귀, 숙지황, 천궁, 작약)의 한방약재에 ginsenoside Rg3가 강화된 흑삼을 첨가한 토너와 로션을 제조하여 주름개선 효과를 평가하였다. 평균연령 42.5세의 한국인 중년여성 6명을 대상으로 토너사용 후 로션사용으로 매일 2회씩(아침, 저녁) 4주간 연속 사용하도록 한 다음, 실험 4주 후에 눈가 주름의 모사판을 제작하여 영상 분석하였다. 또한 연구책임자가 시료의 피부 안전성을 관찰하기 위해 육안 검사도 함께 수행하였다. 눈꼬리 주름 모사판 영상분석 결과, 토너와 로션 사용 4주 후 주름 R1은 $3.15{\pm}0.35$에서 $2.28{\pm}0.22$, R2는 $2.99{\pm}0.37$에서 $2.13{\pm}0.21$, R3는 $2.09{\pm}0.31$에서 $1.56{\pm}0.18$, R4는$0.37{\pm}0.05$에서 $0.29{\pm}0.03$, R5는 $0.89{\pm}0.1$에서 $0.75{\pm}0.06$로 유의하게 감소하여(P<0.05), 본 시료는 주름개선에 효과 있는 것으로 확인되었다.

This study evaluated anti-wrinkle effect using toner and lotion containing ginsenoside Rg3 enriched black ginseng in oriental medicine like Liriope platy phyllla, Inonotus obliquus, Glycyrrhiza glabra and nourishing of the blood and energy(Atractylodes japonica, Poria cocos Wolf, Angelica gigas, Rehmanniae Radix Preparata, Cnidii Rhizoma, Paeonia lactiflora). 6 female adults on average at the age of 42.5 applied lotion after toner under the normal conditions of use on the face including crow's feed area, twice a day (in the morning and evening) for 4weeks. After 4 weeks, the replica of eye wrinkle was made and analyzed the image. The result was decreased in R1($3.15{\pm}0.35$ to $2.28{\pm}0.22$), R2($2.99{\pm}0.37$ to $2.13{\pm}0.21$), R3($2.09{\pm}0.31$ to $1.56{\pm}0.18$), R4($0.37{\pm}0.05$ to $0.29{\pm}0.03$), and R5($0.89{\pm}0.1$ to $0.75{\pm}0.06$)(P<0.05). Therefore, oriental medicine cosmetics containing black ginseng may play a role anti-wrinkle.

키워드

참고문헌

  1. EB Doris. Cosmetics & Toiletries. 111:31-37. 1996.
  2. A Oikarinen. The aging of skin:chronoaging versus photoaging, Photodermatol. Photoimmunol. Photomed. 7:3. 1990.
  3. AM Klingman, RM Laver. Cutaneous aging:The difference between intrinsic aging and photoaging. J. Cutan Aging Cosmet Dermatol. 1:5. 1988.
  4. HM Daniel, AnnIntern Med. 75:873-880. 1971.
  5. MJ Grove, J Am Acad Dermatol. 21:631-637. 1989. https://doi.org/10.1016/S0190-9622(89)70230-9
  6. TJ Griffiths et al, Arch Dermatol. 128:347-351. 1992. https://doi.org/10.1001/archderm.128.3.347
  7. KS Weiss et al, JAMA. 259:527-532. 1988. https://doi.org/10.1001/jama.259.4.527
  8. Hermitte. Cosmetics & Toiletries. 107:63-67. 1992
  9. DR Rosenthal et al. J Invest Dermatol. 95:510-515. 1990. https://doi.org/10.1111/1523-1747.ep12504718
  10. TD Ditre et al. J Invest Dermatol. 34:187-195. 1996.
  11. 이상인. 서울:한국인삼경작조합연합회. 한국인삼사. 166. 1980.
  12. Yang HS, Park CG, Yoo YC. Biological activities of the extract of black ginseng. Food Ind. Nutr. 12;1-4. 2007.
  13. Sun BS, Gu LJ, Fang Zm, Wang CY, Wang Z, Sung CK. Determination of 11 ginsenosides in black ginseng developed from panax ginseng by high performance liquid chromatography. Food Sci. Biotechnol. 18:561-564. 2009.
  14. Sun BS, Gu LJ, Fang ZM, Wang CY, Wang Z, Lee MR, Li Z, Li JJ, Sung CK. Simultaneous quantification of 19 ginsenosides in black ginseng developed from panax ginseng by HPLC-ELSD. J. Pharmaceut. Biomed Anal. 50:15-22. 2009. https://doi.org/10.1016/j.jpba.2009.03.025
  15. Jorgen Serup, GBE Jemec. Handbook of Non-Invasive Methods and the Skin. CRC Press. 1995.
  16. Branchet MC, Boisnic S, Frances C et al. Skin thickness changes in normal aging skin. Gerontology. 36:28-35. 1990. https://doi.org/10.1159/000213172
  17. HM Daniel, A study in the epidermiology of "crows feet", Am. Intern.Med. 75:873-880, 1971. https://doi.org/10.7326/0003-4819-75-6-873
  18. MJ Grove, JJ Leyden. Optical profilometry: An objective method for quantification of facial wrinkles. J. Am. Acad. Dermatol. 21:631-637. 1989. https://doi.org/10.1016/S0190-9622(89)70230-9
  19. CE Griffiths, TS Wang, TA Hamilton, JJ Voorhees. A photonumeric scale for the assessment of cutaneous photodamage. Arch. Dermatol. 128:347-351. 1992. https://doi.org/10.1001/archderm.128.3.347
  20. GreenLJ, McCormic A, WeinsterinGD. Photoaging and the skin: The effects of tretinoin. Dermatol Clin. 11:97-105. 1993.
  21. Yaar M, Gilchrest BA. Aging versus photoaging: Phostulated Mechanisms and effectors. J Invest Dermatol Symp Proc. 3:47-51. 1998. https://doi.org/10.1038/jidsp.1998.12

피인용 문헌

  1. The Efficacy of Korean Herbal Cosmetics for Facial Skin Elasticity vol.25, pp.3, 2012, https://doi.org/10.6114/jkood.2012.25.3.150