Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
권호 표지

Retrospective Study of Crystalluria and Urinary Tract Symptoms in Dogs

개에서 발생한 결정뇨와 요로증후군에 대한 후향적 연구

  • Oh, Won-Seok (Hwanggum Animal Medical Center) ;
  • Oh, Tae-Ho (Laboratory of Veterinary Internal Medicine, College of Veterinary Medicine, Kyungpook National University)
  • Accepted : 2010.07.12
  • Published : 2010.08.30
Download PDF
⟨ Previous Next ⟩

Abstract

This retrospective study was performed in 40 cases of canine crystalluria and urinary tract symptoms. Breed, age, sex, diet history and common clinical signs were investigated for patient information. CBC, serum chemistry, urinalysis, urine culture, urine sediment and urinary stone analysis were undertaken for clinicopathological diagnosis. Crystalluria and urinary tract symptoms occurred from 6 months till 14 years in this clinical investigation and the average age was 4.68 years. It had taken an average 7.4 weeks to correct crystalluria and urinary tract symptoms treated by supportive therapy and dietary management. In conclusion, regular clinical pathologic examination, treatment and diet management should be needed to prevent the formation of urolithiasis and urinary tract diseases in dogs with crystalluria and urinary tract symptoms.

Keywords

References

  1. Hering F, Bigalke KH, Lutzeyer W. Interaction of hyperuricuria and hyperoxaluria on renal calcium oxalate stone formation. Adv Exp Med Biol 1980; 122A: 99-107.
  2. Khan SR, Thamilselvan S. Nephrolithiasis: A consequence of renal epithelial cell exposure to oxalate and calcium oxalate crystals. Mol Urol 2000; 4: 305-312.
  3. Lekcharoensuk C, Lulich JP, Osborne CA, Pusoonthornthum R, Allen TA, Koehler LA, Urlich LK, Carpenter KA, Swanson LL. Patient and environmental factors associated with calcium oxalate urolithiasis in dogs. J Am Vet Med Assoc 2000; 217: 515-519. https://doi.org/10.2460/javma.2000.217.515
  4. Lekcharoensuk C, Osborne CA, Lulich JP, Albasan H, Ulrich LK, Koehler LA, Carpenter KA, Swanson LL, Pederson LA. Trends in the frequency of calcium oxalate uroliths in the upper urinary tract of cats. J Am Anim Hosp Assoc 2005; 41: 39-46.
  5. Lekcharoensuk C, Osborne CA, Lulich JP, Pusoonthornthum R, Kirk CA, Ulrich LK, Koehler LA, Carpenter KA, Swanson LL. Association between dietary factors and calcium oxalate and magnesium ammonium phosphate urolithiasis in cats. J Am Vet Med Assoc 2001; 219: 1228-1237. https://doi.org/10.2460/javma.2001.219.1228
  6. Lekcharoensuk C, Osborne CA, Lulich JP, Pusoonthornthum R, Kirk CA, Ulrich LK, Koehler LA, Carpenter KA, Swanson LL. Associations between dietary factors in canned food and formation of calcium oxalate uroliths in dogs. Am J Vet Res 2002; 63: 163-169. https://doi.org/10.2460/ajvr.2002.63.163
  7. Lekcharoensuk C, Osborne CA, Lulich JP, Pusoonthornthum R, Kirk CA, Ulrich LK, Koehler LA, Carpenter KA, Swanson LL. Associations between dry dietary factors and canine calcium oxalate uroliths. Am J Vet Res 2002; 63: 330-337. https://doi.org/10.2460/ajvr.2002.63.330
  8. Lulich JP, Osborne CA, Lekcharoensuk C, Allen TA, Nakagawa Y. Canine calcium oxalate urolithiasis. Case-based applications of therapeutic principles. Vet Clin North Am Small Anim Pract 1999; 29: 123-139.
  9. Lulich JP, Osborne CA, Thumchai R, Lekcharoensuk C, Ulrich LK, Koehler LA, Bird KA, Swanson LL, Nakagawa Y. Epidemiology of canine calcium oxalate uroliths. Identifying risk factors. Vet Clin North Am Small Anim Pract 1999; 29: 113-122.
  10. Marretta SM, Pask AJ, Greene RW, Liu S. Urinary calculi associated with portosystemic shunts in six dogs. J Am Vet Med Assoc 1981; 178: 133-137.
  11. Osborne CA, Clinton CW. Urolithiasis. Terms and concepts. Vet Clin North Am Small Anim Pract 1986; 16: 3-17.
  12. Osborne CA, Clinton CW, Bamman LK, Moran HC, Coston BR, Frost AP. Prevalence of canine uroliths. Minnesota urolith center. Vet Clin North Am Small Anim Pract 1986; 16: 27-44.
  13. Osborne CA, Clinton CW, Kim KM, Mansfield CF. Etiopathogenesis, clinical manifestations, and management of canine silica urolithiasis. Vet Clin North Am Small Anim Pract 1986; 16: 185-207.
  14. Osborne CA, Clinton CW, Moran HC, Bailie NC. Comparison of qualitative and quantitative analyses of canine uroliths. Vet Clin North Am Small Anim Pract 1986; 16: 317-323.
  15. Osborne CA, Klausner JS, Krawiec DR, Griffith DP. Canine struvite urolithiasis: Problems and their dissolution. J Am Vet Med Assoc 1981; 179: 239-244.
  16. Osborne CA, Klausner JS, Polzin DJ, Griffith DP. Etiopathogenesis of canine struvite urolithiasis. Vet Clin North Am Small Anim Pract 1986; 16: 67-86.
  17. Osborne CA, Lulich JP, Polzin DJ, Allen TA, Kruger JM, Bartges JW, Koehler LA, Ulrich LK, Bird KA, Swanson LL. Medical dissolution and prevention of canine struvite urolithiasis. Twenty years of experience. Vet Clin North Am Small Anim Pract 1999; 29: 73-111.
  18. Osborne CA, Lulich JP, Polzin DJ, Sanderson SL, Koehler LA, Ulrich LK, Bird KA, Swanson LL, Pederson LA, Sudo SZ. Analysis of 77,000 canine uroliths. Perspectives from the minnesota urolith center. Vet Clin North Am Small Anim Pract 1999; 29: 17-38.
  19. Osborne CA, O'Brien TD, Ghobrial HK, Meihak L, Stevens JB. Crystalluria. Observations, interpretations, and misinterpretations. Vet Clin North Am Small Anim Pract 1986; 16: 45-65.
  20. Siener R, Ebert D, Nicolay C, Hesse A. Dietary risk factors for hyperoxaluria in calcium oxalate stone formers. Kidney Int 2003; 63: 1037-1043. https://doi.org/10.1046/j.1523-1755.2003.00807.x
  21. Siener R, Hesse A. The effect of different diets on urine composition and the risk of calcium oxalate crystallisation in healthy subjects. Eur Urol 2002; 42: 289-296. https://doi.org/10.1016/S0302-2838(02)00316-0
  22. Siener R, Schade N, Nicolay C, von Unruh GE, Hesse A. The efficacy of dietary intervention on urinary risk factors for stone formation in recurrent calcium oxalate stone patients. J Urol 2005; 173: 1601-1605. https://doi.org/10.1097/01.ju.0000154626.16349.d3
  23. Thamilselvan S, Hackett RL, Khan SR. Lipid peroxidation in ethylene glycol induced hyperoxaluria and calcium oxalate nephrolithiasis. J Urol 1997; 157: 1059-1063. https://doi.org/10.1016/S0022-5347(01)65141-3
  24. Thamilselvan S, Khan SR. Oxalate and calcium oxalate crystals are injurious to renal epithelial cells: Results of in vivo and in vitro studies. J Nephrol 1998; 11(Suppl 1): 66-69.