Comparison of Cortical Activation between Tactile Stimulation and Two-point Discrimination: An fMRI Case Study

촉각 자극과 두점식별 자극에 따른 뇌활성도 분석: fMRI 사례 연구

  • Park, Ji-Won (Department of Physical Therapy, College of Medical Science, Catholic University of Daegu) ;
  • Kim, Chung-Sun (Department of Physical Therapy, College of Rehabilitation, Daegu University)
  • 박지원 (대구가톨릭대학교 의료과학대학 물리치료학과) ;
  • 김중선 (대구대학교 재활과학대학 물리치료학과)
  • Received : 2010.06.15
  • Accepted : 2010.08.16
  • Published : 2010.08.25

Abstract

Purpose: Sensory input is very important for proper performance of human. Two-point discrimination is the most widely used tactile sensory test. The purpose of this study was to find the changes in cortical activation patterns between tactile stimulation and two-point discrimination. Methods: Two healthy subjects participated in our study. fMRI scanning was done during 4 repeated blocks of tactile stimulation and two point discrimination of the right index finger tip. In one block, stimuli were repeated 10 times every three seconds. To determine the changes of cortical neurons during sensory input, intensity index was analyzed. Results: When tactile stimulation of the right index finger tip was completed, only contralateral primary somatosensory area was activated. In contrast, during two-point discrimination, both the primary somatosensory area and ipsilateral supplementary sensory area were activated. Conclusion: During two point discrimination, both primary somatosensory area and ipsilateral supplementary sensory area were activated. Therefore, two-point discrimination is required more complex and conscious activity than tactile stimulation.

Keywords

References

  1. Tamura Y, Hoshiyama M, Inui K et al. Cognitive processes in two-point discrimination: An erp study. Clin Neurophysiol. 2004;115(8):1875-84. https://doi.org/10.1016/j.clinph.2004.03.018
  2. Wallesch CW, Curio N, Galazky I et al. The neuropsychology of blunt head injury in the early postacute stage: Effects of focal lesions and diffuse axonal injury. J Neurotrauma. 2001;18(1):11-20. https://doi.org/10.1089/089771501750055730
  3. Tamura Y, Hoshiyama M, Inui K et al. Central mechanisms for two-point discrimination in humans. Neurosci Lett. 2003;342(3):187-90. https://doi.org/10.1016/S0304-3940(03)00291-X
  4. Morch CD, Andersen OK, Quevedo AS et al. Exteroceptive aspects of nociception: Insights from graphesthesia and two-point discrimination. Pain. 2010.
  5. Lesny I. Disturbance of two-point discrimination sensitivity in different forms of cerebral palsy. Dev Med Child Neurol. 1971;13(3):330-4.
  6. Lesny I, Stehlik A, Tomasek J et al. Sensory disorders in cerebral palsy: Two-point discrimination. Dev Med Child Neurol. 1993;35(5):402-5.
  7. Salanova V, Andermann F, Rasmussen T et al. Tumoural parietal lobe epilepsy. Clinical manifestations and outcome in 34 patients treated between 1934 and 1988. Brain. 1995;118 ( Pt 5):1289-304. https://doi.org/10.1093/brain/118.5.1289
  8. Felmingham KL, Baguley IJ, Crooks J. A comparison of acute and postdischarge predictors of employment 2 years after traumatic brain injury. Arch Phys Med Rehabil. 2001;82(4):435-9.
  9. Fatemi MJ, Jalilimanesh M, Dini MT. Evaluation of moving and static two point discriminations of volar forearm skin before and after transfer as a sensate radial forearm island flap in reconstruction of degloving injury of the thumb. J Plast Reconstr Aesthet Surg. 2007;60(4):356-9. https://doi.org/10.1016/j.bjps.2006.05.001
  10. Lenzenweger MF. Two-point discrimination thresholds and schizotypy: Illuminating a somatosensory dysfunction. Schizophr Res. 2000;42(2):111-24. https://doi.org/10.1016/S0920-9964(99)00120-6
  11. Oldfield RC. The assessment and analysis of handedness: The edinburgh inventory. Neuropsychologia. 1971;9(1): 97-113. https://doi.org/10.1016/0028-3932(71)90067-4
  12. Choi JH, Kwon YH. Medial reorganization of primary motor cortex in patient with traumatic brain injury: A fmri case study. J Kor Soc Phys Ther. 2005;17(3):421-8.
  13. Yang GA, Kim SH, Lim YE et al. Comparison of the activity of cortical neurons according to muscle contraction type between post stroke hemiplegic subjects and healthy subjects. J Kor SocPhys Ther. 2009;21(1):73-80.
  14. Park JW, Jang SH. The difference of cortical activation pattern according to motor learning in dominant and non‐dominant hand: An fmri case study. J Kor Soc Phys Ther. 2009;21(1):8.
  15. Choi JJ, Jang HJ, Hong IP et al. A clinical study on the two-point discrimination of the replanted digits. The korean society of plastic and reconstructive surgeons. 1995;22(3): 615-21.
  16. Heriseanu R, Baguley IJ, Slewa-Younan S. Two-point discrimination following traumatic brain injury. J Clin Neurosci. 2005;12(2):156-60. https://doi.org/10.1016/j.jocn.2004.03.029
  17. Akatsuka K, Noguchi Y, Harada T et al. Neural codes for somatosensory two-point discrimination in inferior parietal lobule: An fmri study. Neuroimage. 2008;40(2):852-8. https://doi.org/10.1016/j.neuroimage.2007.12.013
  18. Pastor MA, Day BL, Macaluso E et al. The functional neuroanatomy of temporal discrimination. J Neurosci. 2004;24(10):2585-91. https://doi.org/10.1523/JNEUROSCI.4210-03.2004
  19. Pastor MA, Macaluso E, Day BL et al. The neural basis of temporal auditory discrimination. Neuroimage. 2006;30(2): 512-20. https://doi.org/10.1016/j.neuroimage.2005.09.053