DOI QR코드

DOI QR Code

Hydrocephalus as a Presenting Manifestation of Neurosarcoidosis : Easy to Misdiagnose as Tuberculosis

  • Lee, Chang-Hyun (Department of Neurosurgery, Seoul National University Hospital) ;
  • Jung, Young-Sub (Department of Neurosurgery, Seoul Metropolitan Government-Seoul National University Boramae Medical Center) ;
  • Lee, Sang-Hyung (Department of Neurosurgery, Seoul Metropolitan Government-Seoul National University Boramae Medical Center)
  • 투고 : 2009.08.06
  • 심사 : 2010.06.10
  • 발행 : 2010.07.28

초록

We present a case of hydrocephalus as the primary manifestation of neurosarcoidosis. Sarcoidosis is a rare disease in Korea and its incidence is much lower than that of tuberculosis. Diagnosis is made by pathologic findings and by exclusion of other granulomatous disorders. Neurosarcoidosis is observed in approximately 5% of sarcoidosis. Its common manifestations are facial palsy (50% of patients with neurosarcoidosis) and optic neuritis. Hydrocephalus is a very uncommon reported finding. Although the typical presentation of sarcoidosis such as facial palsy is not a diagnostic dilemma, more atypical presentations such as hydrocephalus with altered mentality in a tuberculosis patient can lead to a misdiagnosis.

키워드

참고문헌

  1. Allen RK, Sellars RE, Sandstrom PA : A prospective study of 32 patients with neurosarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis 20 : 118-125, 2003
  2. Burns TM : Neurosarcoidosis. Arch Neurol 60 : 1166-1168, 2003 https://doi.org/10.1001/archneur.60.8.1166
  3. James DG, Neville E : Pathobiology of sarcoidosis. Pathobiol Annu 7 : 31-61, 1977
  4. Kim DS : Sarcoidosis in Korea : report of the Second Nationwide Survey. Sarcoidosis Vasc Diffuse Lung Dis 18 : 176-180, 2001
  5. Lower EE, Broderick JP, Brott TG, Baughman RP : Diagnosis and management of neurological sarcoidosis. Arch Intern Med 157 : 1864-1868, 1997 https://doi.org/10.1001/archinte.157.16.1864
  6. Luke RA, Stern BJ, Krumholz A, Johns CJ : Neurosarcoidosis : the long-term clinical course. Neurology 37 : 461-463, 1987 https://doi.org/10.1212/WNL.37.3.461
  7. Rubinstein I, Baum GL, Hiss Y : [Misdiagnosis of sarcoidosis in active pulmonary tuberculosis.] Harefuah 108 : 175-176, 1985
  8. Scott TF : Neurosarcoidosis : progress and clinical aspects. Neurology 43 : 8-12, 1993 https://doi.org/10.1212/WNL.43.1_Part_1.8
  9. Stern BJ, Krumholz A, Johns C, Scott P, Nissim J : Sarcoidosis and its neurological manifestations. Arch Neurol 42 : 909-917, 1985 https://doi.org/10.1001/archneur.1985.04060080095022

피인용 문헌

  1. Hydrocephalus, a rare manifestation of sarcoidosis vol.1, pp.3, 2011, https://doi.org/10.4081/cp.2011.e66
  2. Hydrocephalus with panventricular enlargement as the primary manifestation of neurosarcoidosis: a case report vol.7, pp.1, 2013, https://doi.org/10.1186/1752-1947-7-240
  3. A Case of Neurosarcoidosis Presenting the Obstructive Hydrocephalus with Small Nodules around the Cerebral Aqueduct vol.34, pp.1, 2014, https://doi.org/10.7878/jjsogd.34.69
  4. Hydrocephalus as the first presenting symptom of neurosarcoidosis in two patients: a diagnosis more forthcoming in the context of systemic disease vol.12, pp.8, 2010, https://doi.org/10.1136/bcr-2019-229903
  5. Case of isolated neurosarcoidosis requiring differentiation from tuberculous meningitis vol.60, pp.3, 2010, https://doi.org/10.5692/clinicalneurol.cn-001387