Childhood Arsenic Exposure and Health Risk Assessment from Rice Cultivated Near the Mining Areas in Korea

  • Paik, Min-Kyoung (Department of Crop Life Safety, National Academy of Agricultural Science, Rural Development Administration) ;
  • Kim, Won-Il (Department of Crop Life Safety, National Academy of Agricultural Science, Rural Development Administration) ;
  • Im, Geon-Jae (Department of Crop Life Safety, National Academy of Agricultural Science, Rural Development Administration) ;
  • Hong, Moo-Ki (Department of Crop Life Safety, National Academy of Agricultural Science, Rural Development Administration)
  • 투고 : 2010.04.08
  • 심사 : 2010.05.17
  • 발행 : 2010.06.30

초록

우리나라 유아들이 비소에 노출된 경우의 인체위해성에 대한 상관관계 연구가 미비한 실정이다. 본 연구는 우리나라 광신인근 지역에서 생산된 백미의 섭취를 통한 비소의 노출을 유아기(1-6세)와 타 연령군으로 나누어 평가하고 해당 연령군의 인체위해성 평가를 확률적 접근법을 이용해 실시하였다. 우리나라 광산인근 지역에서 생산된 백미 섭취를 통한 D아기의 비소 노출량은 체중을 기준으로 했을 때 타 연령군에 비해 높게 나타났다. 피부암에 대한 초과발암위해의 경우 1-2세 군과 3-6세 군의 50% percentile값이 각각 만명 당 1.76명과 3.16명으로 나타났다. 어린이와 같은 아만성기간 동안의 비소 노출에 대한 비발암 기준 참고치(0.005 mg/lg/day)를 적용한 결과 비발암위해도의 평균값 뿐 아니라 고섭취군을 나타내는 95% percentile 값 또한 규제수치인 1.0 이하로 나타났다.

Domestic studies for identification of causality between children exposure to toxic chemicals, such as arsenic (As) and resulted hazardous effects were not implemented. This study was conducted to probabilistically estimate dietary As intake and health risk assessment for young children and all age-specific populations from the consumption of As-contaminated rice of Korea. Arsenic intakes for young children (1 to 6 years old) from As-contaminated rice were higher than other age-specific groups, based on a dose-per-body weight basis. Based on the current EPA cancer slope factor for As, estimated cancer risks (to the skin cancer) associated with dietary intake of As-contaminated rice for 1 to 2 years old group and 3 to years old group are 1.76 per 10,000 and 3.16 per 10,000, respectively, at the 50th percentile. Based on possible reference levels (0.005 mg/kg/day) for children, mean and $95^{th}$ percentile value of HQ from rice for young children are very below 1.0, which is a regulatory limit of non-carcinogenic risks for human.

키워드

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