References
- Adachi, T., Pimentel, D.R., Heibeck, T., Hou, X., Lee, Y.J., Jiang, B., Ido, Y. and Cohen, R.A. (2004). S-Glutathiolation of Ras mediates redox-sensitive signaling by angiotensin II in vascular smooth muscle cells. J. Biol. Chem., 279, 29857-29862. https://doi.org/10.1074/jbc.M313320200
- Ambrosone, C.B., Freudenheim, J.L., Thompson, P.A., Bowman, E., Vena, J.E., Marshall, J.R., Graham, S., Laughlin, R., Nemoto, T. and Shields, P.G. (1999). Manganese superoxide dismutase (MnSOD) genetic polymorphisms, dietary antioxidants, and risk of breast cancer. Cancer Res., 59, 602-606.
- Asikainen, T.M., Raivio, K.O., Saksela, M. and Kinnula, V.L. (1998). Expression and developmental profile of antioxidant enzymes in human lung and liver. Am. J. Respir. Cell Mol. Biol., 19, 942-949. https://doi.org/10.1165/ajrcmb.19.6.3248
- Borgstahl, G.E., Parge, H.E., Hickey, M.J., Beyer, W.F., Jr., Hallewell, R.A. and Tainer, J.A. (1992). The structure of human mitochondrial manganese superoxide dismutase reveals a novel tetrameric interface of two 4-helix bundles. Cell, 71, 107-118. https://doi.org/10.1016/0092-8674(92)90270-M
- Borgstahl, G.E.O., Parge, H.E., Hickey, M.J., Johnson, M.J., Boissinot, M., Hallewell, R.A., Lepock, J.R., Cabelli, D.E. and Tainer, J.A. (1996). Human mitochondrial manganese superoxide dismutase polymorphic variant Ile58Thr reduces activity by destabilizing the tetrameric interface. Biochemistry (Mosc), 35, 4287-4297. https://doi.org/10.1021/bi951892w
- Brabletz, T., Jung, A., Spaderna, S., Hlubek, F. and Kirchner, T. (2005). Opinion: Migrating cancer stem cells - an integrated concept of malignant tumour progression. Nat. Rev. Cancer, 5, 744-749. https://doi.org/10.1038/nrc1694
- Buettner, G.R. and Jurkiewicz, B.A. (1993). Ascorbate free radical as a marker of oxidative stress: An EPR study. Free Radic. Biol. Med., 14, 49-55. https://doi.org/10.1016/0891-5849(93)90508-R
-
Buettner, G.R., Ng, C.F., Wang, M., Rodgers, V.G.J. and Schafer, F.Q. (2006). A new paradigm: Manganese superoxide dismutase influences the production of
$H_2O_2$ in cells and thereby their biological state. Free Radic. Biol. Med., 41, 1338-1350. https://doi.org/10.1016/j.freeradbiomed.2006.07.015 - Cadenas, E. and Davies, K.J.A. (2000). Mitochondrial free radical generation, oxidative stress, and aging. Free Radic. Biol. Med., 29, 222-230. https://doi.org/10.1016/S0891-5849(00)00317-8
- Cai, Q., Shu, X.O., Wen, W., Cheng, J.R., Dai, Q., Gao, Y.T. and Zheng, W. (2004). Genetic polymorphism in the manganese superoxide dismutase gene, antioxidant intake, and breast cancer risk: Results from the Shanghai Breast Cancer Study. Breast Cancer Res., 6, R647-655. https://doi.org/10.1186/bcr929
- Castellano, I., Cecere, F., De Vendittis, A., Cotugno, R., Chambery, A., Di Maro, A., Michniewicz, A., Parlato, G., Masullo, M., Avvedimento, E.V., De Vendittis, E. and Ruocco, M.R. (2009). Rat mitochondrial manganese superoxide dismutase: Amino acid positions involved in covalent modifications, activity, and heat stability. Biopolymers, 91, 1215-1226. https://doi.org/10.1002/bip.21208
- Cheng, T.C., Chen, S.T., Huang, C.S., Fu, Y.P., Yu, J.C., Cheng, C.W., Wu, P.E. and Shen, C.Y. (2005). Breast cancer risk associated with genotype polymorphism of the catechol estrogenmetabolizing genes: A multigenic study on cancer susceptibility. Int. J. Cancer, 113, 345-353. https://doi.org/10.1002/ijc.20630
- Choi, J.-Y., Neuhouser, M.L., Barnett, M., Hudson, M., Kristal, A.R., Thornquist, M., King, I.B., Goodman, G.E. and Ambrosone, C.B. (2007). Polymorphisms in oxidative stress-related genes are not associated with prostate cancer risk in heavy smokers. Cancer Epidemiol. Biomarkers Prev., 16, 1115-1120. https://doi.org/10.1158/1055-9965.EPI-07-0040
- Chung, D.J., Wright, A.E. and Clerch, L.B. (1998). The 3' untranslated region of manganese superoxide dismutase RNA contains a translational enhancer element. Biochemistry (Mosc), 37, 16298-16306. https://doi.org/10.1021/bi980935g
- Church, S.L., Grant, J.W., Meese, E.U. and Trent, J.M. (1992). Sublocalization of the gene encoding manganese superoxide dismutase (MnSOD/SOD2) to 6q25 by fluorescence in situ hybridization and somatic cell hybrid mapping. Genomics, 14, 823-825. https://doi.org/10.1016/S0888-7543(05)80202-2
- Clerch, L.B., Massaro, D. and Berkovich, A. (1998). Molecular mechanisms of antioxidant enzyme expression in lung during exposure to and recovery from hyperoxia. Am. J. Physiol. Lung Cell Mol. Physiol., 274, L313-319.
- Connor, K.M., Hempel, N., Nelson, K.K., Dabiri, G., Gamarra, A., Belarmino, J., Van De Water, L., Mian, B.M. and Melendez, J.A. (2007). Manganese superoxide dismutase enhances the invasive and migratory activity of tumor cells. Cancer Res., 67, 10260-10267. https://doi.org/10.1158/0008-5472.CAN-07-1204
- Davis, C.A., Hearn, A.S., Fletcher, B., Bickford, J., Garcia, J.E., Leveque, V., Melendez, J.A., Silverman, D.N., Zucali, J., Agarwal, A. and Nick, H.S. (2004). Potent anti-tumor effects of an active site mutant of human manganese-superoxide dismutase: Evolutionary conservation of product inhibition. J. Biol. Chem., 279, 12769-12776. https://doi.org/10.1074/jbc.M310623200
- Davis, C.A., Monnier, J.M. and Nick, H.S. (2001). A coding region determinant of instability regulates levels of manganese superoxide dismutase mRNA. J. Biol. Chem., 276, 37317-37326. https://doi.org/10.1074/jbc.M104378200
- Dionisi, O., Galeotti, T., Terranova, T. and Azzi, A. (1975). Superoxide radicals and hydrogen peroxide formation in mitochondria from normal and neoplastic tissues. Biochim. Biophys. Acta, 403, 292-300. https://doi.org/10.1016/0005-2744(75)90059-5
- Droge, W. (2002). Free radicals in the physiological control of cell function. Physiol. Rev., 82, 47-95.
- Egan, K.M., Thompson, P.A., Titus-Ernstoff, L., Moore, J.H. and Ambrosone, C.B. (2003). MnSOD polymorphism and breast cancer in a population-based case-control study. Cancer Lett., 199, 27-33. https://doi.org/10.1016/S0304-3835(03)00349-5
- Eras-Erdogan, N., Akbas, E., Senli, H., Kul, S. and Colak, T. (2009). Relationship between polymorphism in the manganese superoxide dismutase gene and breast cancer. Mutat. Res., 680, 7-11. https://doi.org/10.1016/j.mrgentox.2009.08.006
- Ford, D., Hoe, N., Landis, G.N., Tozer, K., Luu, A., Bhole, D., Badrinath, A. and Tower, J. (2007). Alteration of drosophila life span using conditional, tissue-specific expression of transgenes triggered by doxycyline or RU486/Mifepristone. Exp. Gerontol., 42, 483-497. https://doi.org/10.1016/j.exger.2007.01.004
- Ginsberg, M.D., Feliciello, A., Jones, J.K., Avvedimento, E.V. and Gottesman, M.E. (2003). PKA-dependent binding of mRNA to the mitochondrial AKAP121 protein. J. Mol. Biol., 327, 885-897. https://doi.org/10.1016/S0022-2836(03)00173-6
- Gotoh, N. and Niki, E. (1992). Rates of interactions of superoxide with vitamin E, vitamin C and related compounds as measured by chemiluminescence. Biochim. Biophys. Acta, 1115, 201-207. https://doi.org/10.1016/0304-4165(92)90054-X
- Grasbon-Frodl, E.M., Kosel, S., Riess, O., Muller, U., Mehraein, P. and Graeber, M.B. (1999). Analysis of mitochondrial targeting sequence and coding region polymorphisms of the manganese superoxide dismutase gene in German Parkinson Disease patients. Biochem. Biophys. Res. Commun., 255, 749-752. https://doi.org/10.1006/bbrc.1998.9998
- Guo, Z., Boekhoudt, G.H. and Boss, J.M. (2003). Role of the intronic enhancer in tumor necrosis factor-mediated induction of manganous superoxide dismutase. J. Biol. Chem., 278, 23570-23578. https://doi.org/10.1074/jbc.M303431200
- Hermann, B., Li, Y., Ray, M.B., Wo, J.M. and Martin, R.C.G., II. (2005). Association of manganese superoxide dismutase expression with progression of carcinogenesis in Barrett Esophagus. Arch. Surg., 140, 1204-1209. https://doi.org/10.1001/archsurg.140.12.1204
- Hernandez-Saavedra, D. and McCord, J.M. (2003). Paradoxical effects of thiol reagents on Jurkat cells and a new thiol-sensitive mutant form of human mitochondrial superoxide dismutase. Cancer Res., 63, 159-163.
- Ho, J.C., Mak, J.C., Ho, S.P., Ip, M.S., Tsang, K.W., Lam, W.K. and Chan-Yeung, M. (2006). Manganese superoxide dismutase and catalase genetic polymorphisms, activity levels, and lung cancer risk in Chinese in Hong Kong. J. Thorac. Oncol., 1, 648-653. https://doi.org/10.1097/01243894-200609000-00008
- Ho, Y.-S. and Crapo, J.D. (1988). Isolation and characterization of complementary DNAs encoding human manganese-containing superoxide dismutase. FEBS Lett., 229, 256-260. https://doi.org/10.1016/0014-5793(88)81136-0
- Hopper, R.K., Carroll, S., Aponte, A.M., Johnson, D.T., French, S., Shen, R.F., Witzmann, F.A., Harris, R.A. and Balaban, R.S. (2006). Mitochondrial matrix phosphoproteome: Effect of extra mitochondrial calcium. Biochemistry (Mosc), 45, 2524-2536. https://doi.org/10.1021/bi052475e
- Huang, Y., Peng, J., Oberley, L.W. and Domann, F.E. (1997). Transcriptional inhibition of manganese superoxide dismutase (SOD2) gene expression by DNA methylation of the 5' CpG island. Free Radic. Biol. Med., 23, 314-320. https://doi.org/10.1016/S0891-5849(97)00095-6
- Izutani, R., Asano, S., Imano, M., Kuroda, D., Kato, M. and Ohyanagi, H. (1998). Expression of manganese superoxide dismutase in esophageal and gastric cancers. J. Gastroenterol., 33, 816-822. https://doi.org/10.1007/s005350050181
- Jang, Y.C. and Remmen, V.H. (2009). The mitochondrial theory of aging: Insight from transgenic and knockout mouse models. Exp. Gerontol., 44, 256-260. https://doi.org/10.1016/j.exger.2008.12.006
- Janssen, A.M., Bosman, C.B., Kruidenier, L., Griffioen, G., Lamers, C.B., van Krieken, J.H., van de Velde, C.J. and Verspaget, H.W. (1999). Superoxide dismutases in the human colorectal cancer sequence. J. Cancer Res. Clin. Oncol., 125, 327-335. https://doi.org/10.1007/s004320050282
- Janssen, A.M., Bosman, C.B., van Duijn, W., Oostendorp-van de Ruit, M.M., Kubben, F.J., Griffioen, G., Lamers, C.B., van Krieken, J.H., van de Velde, C.J. and Verspaget, H.W. (2000). Superoxide dismutases in gastric and esophageal cancer and the prognostic impact in gastric cancer. Clin. Cancer Res., 6, 3183-3192.
- Kang, D., Lee, K.-M., Park, S.K., Berndt, S.I., Peters, U., Reding, D., Chatterjee, N., Welch, R., Chanock, S., Huang, W.-Y. and Hayes, R.B. (2007). Functional variant of manganese superoxide dismutase (SOD2 V16A) polymorphism is associated with prostate cancer risk in the prostate, lung, colorectal, and ovarian cancer study. Cancer Epidemiol. Biomarkers Prev., 16, 1581-1586. https://doi.org/10.1158/1055-9965.EPI-07-0160
- Kim, A., Joseph, S., Khan, A., Epstein, C.J., Sobel, R. and Huang, T.T. (2010). Enhanced expression of mitochondrial superoxide dismutase leads to prolonged in vivo cell cycle progression and up-regulation of mitochondrial thioredoxin. Free Radic. Biol. Med., 43, 1501-1512.
- Kim, A., Murphy, M.P. and Oberley, T.D. (2005a). Mitochondrial redox state regulates transcription of the nuclear-encoded mitochondrial protein manganese superoxide dismutase: A proposed adaptive response to mitochondrial redox imbalance. Free Radic. Biol. Med., 38, 644-654. https://doi.org/10.1016/j.freeradbiomed.2004.10.030
- Kim, A., Oberley, L.W. and Oberley, T.D. (2005b). Induction of apoptosis by adenovirus-mediated manganese superoxide dismutase overexpression in SV-40-transformed human fibroblasts. Free Radic. Biol. Med., 39, 1128-1141. https://doi.org/10.1016/j.freeradbiomed.2005.06.007
- Kim, A., Zhong, W. and Oberley, T.D. (2004). Reversible modulation of cell cycle kinetics in NIH/3T3 mouse fibroblasts by inducible overexpression of mitochondrial manganese superoxide dismutase. Antioxid. Redox Signal., 6, 489-500. https://doi.org/10.1089/152308604773934251
- Kim, H.-P., Roe, J.-H., Chock, P.B. and Yim, M.B. (1999). Transcriptional activation of the human manganese superoxide dismutase gene mediated by tetradecanoylphorbol acetate. J. Biol. Chem., 274, 37455-37460. https://doi.org/10.1074/jbc.274.52.37455
- Kinnula, V.L. and Crapo, J.D. (2004). Superoxide dismutases in malignant cells and human tumors. Free Radic. Biol. Med., 36, 718-744. https://doi.org/10.1016/j.freeradbiomed.2003.12.010
- Klaunig, J.E., Kamendulis, L.M. and Hocevar, B.A. (2010). Oxidative stress and oxidative damage in carcinogenesis. Toxicol. Pathol., 38, 96-109. https://doi.org/10.1177/0192623309356453
- Knirsch, L. and Clerch, L.B. (2001). Tyrosine phosphorylation regulates manganese superoxide dismutase (MnSOD) RNAbinding protein activity and MnSOD protein expression. Biochemistry (Mosc), 40, 7890-7895. https://doi.org/10.1021/bi010197n
- Kocabas, N.A., Sardas, S., Cholerton, S., Daly, A.K., Elhan, A.H. and Karakaya, A.E. (2005). Genetic polymorphism of manganese superoxide dismutase(MnSOD) and breast cancer susceptibility. Cell Biochem. Funct., 23, 73-76. https://doi.org/10.1002/cbf.1128
- Kops, G.J., Dansen, T.B., Polderman, P.E., Saarloos, I., Wirtz, K.W., Coffer, P.J., Huang, T.T., Bos, J.L., Medema, R.H. and Burgering, B.M. (2002). Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature, 419, 316-321. https://doi.org/10.1038/nature01036
- Kuo, S., Chesrown, S.E., Mellott, J.K., Rogers, R.J., Hsu, J.-L. and Nick, H.S. (1999). In vivo architecture of the manganese superoxide dismutase promoter. J. Biol. Chem., 274, 3345-3354. https://doi.org/10.1074/jbc.274.6.3345
- Lan, Q., Mumford, J.L., Shen, M., DeMarini, D.M., Bonner, M.R., He, X., Yeager, M., Welch, R., Chanock, S., Tian, L., Chapman, R.S., Zheng, T., Keohavong, P., Caporaso, N. and Rothman, N. (2004). Oxidative damage-related genes AKR1C3 and OGG1 modulate risks for lung cancer due to exposure to PAHrich coal combustion emissions. Carcinogenesis, 25, 2177-2181. https://doi.org/10.1093/carcin/bgh240
- Li, H., Kantoff, P.W., Giovannucci, E., Leitzmann, M.F., Gaziano, J.M., Stampfer, M.J. and Ma, J. (2005). Manganese superoxide dismutase polymorphism, prediagnostic antioxidant status, and risk of clinical significant prostate cancer. Cancer Res., 65, 2498-2504. https://doi.org/10.1158/0008-5472.CAN-04-3535
- Li, N. and Oberley, T.D. (1998). Modulation of antioxidant enzymes, reactive oxygen species, and glutathione levels in manganese superoxide dismutase-overexpressing NIH/3T3 fibroblasts during the cell cycle. J. Cell. Physiol., 177, 148-160. https://doi.org/10.1002/(SICI)1097-4652(199810)177:1<148::AID-JCP16>3.0.CO;2-9
- Li, N., Oberley, T.D., Oberley, L.W. and Zhong, W. (1998). Inhibition of cell growth in NIH/3T3 fibroblasts by overexpression of manganese superoxide dismutase: Mechanistic studies. J. Cell. Physiol., 175, 359-369. https://doi.org/10.1002/(SICI)1097-4652(199806)175:3<359::AID-JCP14>3.0.CO;2-0
- Li, S., Yan, T., Yang, J.-Q., Oberley, T.D. and Oberley, L.W. (2000). The role of cellular glutathione peroxidase redox regulation in the suppression of tumor cell growth by manganese superoxide dismutase. Cancer Res., 60, 3927-3939.
- Lin, P., Hsueh, Y.-M., Ko, J.-L., Liang, Y.-F., Tsai, K.-J. and Chen, C.-Y. (2003). Analysis of NQO1, GSTP1, and MnSOD genetic polymorphisms on lung cancer risk in Taiwan. Lung Cancer, 40, 123-129. https://doi.org/10.1016/S0169-5002(03)00027-8
-
Liochev, S.I. and Fridovich, I. (2007). The effects of superoxide dismutase on
$H_2O_2$ formation. Free Radic. Biol. Med., 42, 1465. https://doi.org/10.1016/j.freeradbiomed.2007.02.015 - MacMillan-Crow, L.A., Crow, J.P. and Thompson, J.A. (1998). Peroxynitrite-mediated inactivation of manganese superoxide dismutase involves nitration and oxidation of critical tyrosine residues. Biochemistry (Mosc), 37, 1613-1622. https://doi.org/10.1021/bi971894b
- Malafa, M., Margenthaler, J., Webb, B., Neitzel, L. and Christophersen, M. (2000). MnSOD expression is increased in metastatic gastric cancer. J. Surg. Res., 88, 130-134. https://doi.org/10.1006/jsre.1999.5773
- Mao, C., Qiu, L.X., Zhan, P., Xue, K., Ding, H., Du, F.B., Li, J. and Chen, Q. (2009). MnSOD Val(16)Ala polymorphism and prostate cancer susceptibility: A meta-analysis involving 8,962 subjects. J. Cancer Res. Clin. Oncol., Epub ahead of print.
- Melendez, J.A. and Baglioni, C. (1993). Differential induction and decay of manganese superoxide dismutase mRNAs. Free Radic. Biol. Med., 14, 601-608. https://doi.org/10.1016/0891-5849(93)90141-G
- Miao, L. and St Clair, D.K. (2009). Regulation of superoxide dismutase genes: Implications in disease. Free Radic. Biol. Med., 47, 344-356. https://doi.org/10.1016/j.freeradbiomed.2009.05.018
- Millikan, R., Player, J., de Cotret, A., Moorman, P., Pittman, G., Vannappagari, V., Tse, C.-K. and Keku, T. (2004). Manganese superoxide dismutase Ala-9Val polymorphism and risk of breast cancer in a population-based case-control study of African Americans and whites. Breast Cancer Res., 6, R264-R274. https://doi.org/10.1186/bcr786
- Mitrunen, K., Sillanpaa, P., Kataja, V., Eskelinen, M., Kosma, V.-M., Benhamou, S., Uusitupa, M. and Hirvonen, A. (2001). Association between manganese superoxide dismutase (MnSOD) gene polymorphism and breast cancer risk. Carcinogenesis, 22, 827-829. https://doi.org/10.1093/carcin/22.5.827
- Oberley, L.W. (2001). Anticancer therapy by overexpression of superoxide dismutase. Antioxid. & Redox Signal., 3, 461-472. https://doi.org/10.1089/15230860152409095
- Oberley, L.W. (2005). Mechanism of the tumor suppressive effect of MnSOD overexpression. Biomed. Pharmacother., 59, 143-148. https://doi.org/10.1016/j.biopha.2005.03.006
- Oberley, L.W. and Buettner, G.R. (1979). Role of superoxide dismutase in cancer: A Review. Cancer Res., 39, 1141-1149.
- Oberley, L.W., Oberley, T.D. and Buettner, G.R. (1980). Cell differentation, aging and cancer: The possible roles of superoxide and superoxide dismutases. Med. Hypotheses, 6, 249-268. https://doi.org/10.1016/0306-9877(80)90123-1
- Oberley, L.W., Oberley, T.D. and Buettner, G.R. (1981). Cell division in normal and transformed cells: The possible role of superoxide and hydrogen peroxide. Med. Hypotheses, 7, 21-42. https://doi.org/10.1016/0306-9877(81)90018-9
- Oberley, T.D., Schultz, J.L., Li, N. and Oberley, L.W. (1995). Antioxidant enzyme levels as a function of growth state in cell culture. Free Radic. Biol. Med., 19, 53-65. https://doi.org/10.1016/0891-5849(95)00012-M
- Oberley, T.D., Xue, Y., Zhao, Y., Kiningham, K., Szweda, L.I. and St Clair, D.K. (2004). In situ reduction of oxidative damage, increased cell turnover, and delay of mitochondrial injury by overexpression of manganese superoxide dismutase in a multistage skin carcinogenesis model. Antioxid. Redox Signal., 6, 537-548. https://doi.org/10.1089/152308604773934297
- Raineri, I., Carlson, E.J., Gacayan, R., Carra, S., Oberley, T.D., Huang, T.-T. and Epstein, C.J. (2001). Strain-dependent highlevel expression of a transgene for manganese superoxide dismutase is associated with growth retardation and decreased fertility. Free Radic. Biol. Med., 31, 1018-1030. https://doi.org/10.1016/S0891-5849(01)00686-4
- Rhee, S.G., Chang, T.S., Bae, Y.S., Lee, S.R. and Kang, S.W. (2003). Cellular regulation by hydrogen peroxide. J. Am. Soc. Nephrol., 14, S211-215. https://doi.org/10.1097/01.ASN.0000077404.45564.7E
-
Rodriguez, A.M., Carrico, P.M., Mazurkiewicz, J.E. and Melendez, J.A. (2000). Mitochondrial or cytosolic catalase reverses the MnSOD-dependent inhibition of proliferation by enhancing respiratory chain activity, net ATP production, and decreasing the steady state levels of
$H_2O_2$ . Free Radic. Biol. Med., 29, 801-813. https://doi.org/10.1016/S0891-5849(00)00362-2 - Rogers, R.J., Monnier, J.M. and Nick, H.S. (2001). Tumor necrosis factor-alpha selectively induces MnSOD expression via mitochondria-to-nucleus signaling, whereas interleukin-1beta utilizes an alternative pathway. J. Biol. Chem., 276, 20419-20427. https://doi.org/10.1074/jbc.M008915200
- Sahu, S.K., Oberley, L.W., Stevens, R.H. and Riley, E.F. (1977). Superoxide dismutase activity of Ehrlich ascites tumor cells. J. Natl. Cancer Inst., 58, 1125-1128.
- Schafer, F.Q. and Buettner, G.R. (2001). Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. Free Radic. Biol. Med., 30, 1191-1212. https://doi.org/10.1016/S0891-5849(01)00480-4
- Schieke, S.M. and Finkel, T. (2006). Mitochondrial signaling, TOR, and life span. Biol. Chem., 387, 1357-1361. https://doi.org/10.1515/BC.2006.170
- Shimoda-Matsubayashi, S., Matsumine, H., Kobayashi, T., Nakagawa-Hattori, Y., Shimizu, Y. and Mizuno, Y. (1996). Structural dimorphism in the mitochondrial targeting sequence in the human manganese superoxide dismutase gene: A predictive evidence for conformational change to influence mitochondrial transport and a study of allelic association in Parkinson's Disease.Biochem. Biophys. Res. Commun., 226, 561-565. https://doi.org/10.1006/bbrc.1996.1394
- Silva, S.N., Cabral, M.N., Bezerra de Castro, G., Pires, M., Azevedo, A.P., Manita, I., Pina, J.E., Rueff, J. and Gaspar, J. (2006). Breast cancer risk and polymorphisms in genes involved in metabolism of estrogens (CYP17, HSD17beta1, COMT and MnSOD): Possible protective role of MnSOD gene polymorphism Val/Ala and Ala/Ala in women that never breast fed. Oncol. Rep., 16, 781-788.
- Slanger, T.E., Chang-Claude, J. and Wang-Gohrke, S. (2006). Manganese superoxide dismutase Ala-9Val polymorphism, environmental modifiers, and risk of breast cancer in a German population. Cancer Causes Control, 17, 1025-1031. https://doi.org/10.1007/s10552-006-0043-5
- Spitz, D.R., Sim, J.E., Ridnour, L.A., Galoforo, S.S. and Lee, Y.J. (2000). Glucose deprivation-induced oxidative stress in human tumor cells: A fundamental defect in metabolism? Ann. N. Y. Acad. Sci., 899, 349-362.
- St. Clair, D., Zhao, Y., Chaiswing, L. and Oberley, T. (2005). Modulation of skin tumorigenesis by SOD. Biomed. Pharmacother., 59, 209-214. https://doi.org/10.1016/j.biopha.2005.03.004
- Sutton, A., Imbert, A., Igoudjil, A., Descatoire, V., Cazanave, S., Pessayre, D. and Degoul, F. (2005). The manganese superoxide dismutase Ala16Val dimorphism modulates both mitochondrial import and mRNA stability. Pharmacogenet. Genomics, 15, 311-319. https://doi.org/10.1097/01213011-200505000-00006
- Sutton, A., Khoury, H., Prip-Buus, C., Cepanec, C., Pessayre, D. and Degoul, F. (2003). The Ala16Val genetic dimorphism modulates the import of human manganese superoxide dismutase into rat liver mitochondria. Pharmacogenetics, 13, 145-157. https://doi.org/10.1097/00008571-200303000-00004
- Trosko, J.E. (2003). Human stem cells as targets for the aging and diseases of aging processes. Med. Hypotheses, 60, 439-447. https://doi.org/10.1016/S0306-9877(02)00446-2
- Wang, L.I., Neuberg, D. and Christiani, D.C. (2004). Asbestos exposure, manganese superoxide dismutase (MnSOD) genotype, and lung cancer risk. J. Occup. Environ. Med., 46, 556-564. https://doi.org/10.1097/01.jom.0000128155.86648.a4
- Weinberg, F. and Chandel, N.S. (2009). Reactive oxygen speciesdependent signaling regulates cancer. Cell. Mol. Life Sci., 66, 3663-3673. https://doi.org/10.1007/s00018-009-0099-y
- Wenk, J., Brenneisen, P., Wlaschek, M., Poswig, A., Briviba, K., Oberley, T.D. and Scharffetter-Kochanek, K. (1999). Stable overexpression of manganese superoxide dismutase in mitochondria identifies hydrogen peroxide as a major oxidant in the AP-1-mediated induction of matrix-degrading metalloprotease-1. J. Biol. Chem., 274, 25869-25876. https://doi.org/10.1074/jbc.274.36.25869
-
Woodson, K., Tangrea, J.A., Lehman, T.A., Modali, R., Taylor, K.M., Snyder, K., Taylor, P.R., Virtamo, J. and Albanes, D. (2003). Manganese superoxide dismutase (MnSOD) polymorphism,
$\alpha$ -tocopherol supplementation and prostate cancer risk in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study (Finland). Cancer Causes Control., 14, 513-518. https://doi.org/10.1023/A:1024840823328 - Xu, Y., Krishnan, A., Wan, X.S., Majima, H., Yeh, C.C., Ludewig, G., Kasarskis, E.J. and St Clair, D.K. (1999). Mutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells. Oncogene, 18, 93-102. https://doi.org/10.1038/sj.onc.1202265
- Xu, Y., Porntadavity, S. and St Clair, D.K. (2002). Transcriptional regulation of the human manganese superoxide dismutase gene: The role of specificity protein 1 (Sp1) and activating protein-2 (AP-2). Biochem. J., 362, 401-412. https://doi.org/10.1042/0264-6021:3620401
- Yamanaka, N. and Deamer, D. (1974). Superoxide dismutase activity in WI-38 cell cultures: Effects of age, trypsinization and SV-40 transformation. Physiol. Chem. Phys., 6, 95-106.
- Yeh, C.C., Wan, X.S. and St Clair, D.K. (1998). Transcriptional regulation of the 5' proximal promoter of the human manganese superoxide dismutase gene. DNA Cell. Biol., 17, 921-930. https://doi.org/10.1089/dna.1998.17.921
- Zhang, H.J., Yan, T., Oberley, T.D. and Oberley, L.W. (1999). Comparison of effects of two polymorphic variants of manganese superoxide dismutase on human breast MCF-7 cancer cell phenotype. Cancer Res., 59, 6276-6283.
- Zhang, H.J., Zhao, W., Venkataraman, S., Robbins, M.E.C., Buettner, G.R., Kregel, K.C. and Oberley, L.W. (2002). Activation of matrix metalloproteinase-2 by overexpression of manganese superoxide dismutase in human breast cancer MCF-7 cells involves reactive oxygen species. J. Biol. Chem., 277, 20919-20926. https://doi.org/10.1074/jbc.M109801200
- Zhao, Y., Chaiswing, L., Oberley, T.D., Batinic-Haberle, I., St Clair, W., Epstein, C.J. and St Clair, D. (2005). A mechanismbased antioxidant approach for the reduction of skin carcinogenesis. Cancer Res., 65, 1401-1405. https://doi.org/10.1158/0008-5472.CAN-04-3334
- Zhao, Y., Oberley, T.D., Chaiswing, L., Lin, S.M., Epstein, C.J., Huang, T.T. and St Clair, D. (2002). Manganese superoxide dismutase deficiency enhances cell turnover via tumor promoterinduced alterations in AP-1 and p53-mediated pathways in a skin cancer model. Oncogene, 21, 3836-3846. https://doi.org/10.1038/sj.onc.1205477
- Zhao, Y., Xue, Y., Oberley, T.D., Kiningham, K.K., Lin, S.-M., Yen, H.-C., Majima, H., Hines, J. and St. Clair, D. (2001). Overexpression of manganese superoxide dismutase suppresses tumor formation by modulation of activator protein-1 signaling in a multistage skin carcinogenesis model. Cancer Res., 61, 6082-6088.
- Zhu, C.-H., Huang, Y., Oberley, L.W. and Domann, F.E. (2001). A family of AP-2 proteins down-regulate manganese superoxide dismutase expression. J. Biol. Chem., 276, 14407-14413.
- Zhu, C., Huang, Y., Weydert, C.J., Oberley, L.W. and Domann, F.E. (2001). Constitutive activation of transcription factor AP-2 is associated with decreased MnSOD expression in transformed human lung fibroblasts. Antioxid. Redox Signal., 3, 387-395. https://doi.org/10.1089/15230860152409031
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