Restorative Dentistry and Endodontics

  • 제35권4호
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  • Pages.238-245
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  • 2010
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  • 2234-7658(pISSN)
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  • 2234-7666(eISSN)
대한치과보존학회 (The Korean Academy of Conservative Dentistry)
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치수/치근단 질환에 이환된 영구치의 치수 조직 재생과 치근 형성

PULP TISSUE REGENERATION AND ROOT FORMATION OF PERMANENT TEETH WITH PULPAL/PERIAPICAL DISEASES

  • 유연지 (서울대학교 치의학대학원 치과보존학교실) ;
  • 백승호 (서울대학교 치의학대학원 치과보존학교실) ;
  • 손호현 (서울대학교 치의학대학원 치과보존학교실)
  • Yoo, Yeon-Jee (Department of Conservative Dentistry, School of Dentistry, Seoul National University) ;
  • Baek, Seung-Ho (Department of Conservative Dentistry, School of Dentistry, Seoul National University) ;
  • Son, Ho-Hyun (Department of Conservative Dentistry, School of Dentistry, Seoul National University)
  • 투고 : 2010.06.23
  • 심사 : 2010.06.30
  • 발행 : 2010.07.30
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초록

최근 치수 질환 또는 치근단 질환을 가진 미성숙 영구치에 대한 보존적 치료의 방법으로 여러가지 근관 내 소독 약제를 이용하여 증상 개선은 물론 치근의 성장 및 치수의 재생이 이루어진 증례들이 보고되고 있다. 그 기전에 대해서는 아직 명확하게 밝혀지지는 않았지만 여러가지 줄기 세포 또는 미분화 간엽 세포들이 관여하는 것으로 생각되며, 실제로 재생된 조직에서는 대부분 백악질양 또는 골양 물질의 침착이 관찰되고 있다. 이 새롭고 보존적인 치료 접근 방법은 다능성 줄기 세포와 다양한 조직 공학 기술에 대한 연구와 더불어, 재생적 근관 치료에 더 밝은 비전을 제시하고 있다.

Numerous cases about additional growth of roots or pulp tissue regeneration by using various intracanal medicaments in immature permanent teeth with periapical or pulpal disease have been reported. The underlying mechanism has not been clearly delineated, but it has been widely accepted that undifferentiated mesenchymal cells and stem cells are involved. Moreover, the growth and deposition of osteoid or cementoid tissues have been observed in regenerated pulp and roots. This new and non-invasive treatment has brightened the future of endodontics, and enlarged the vision of regenerative root canal treatment with multi-potent stem cells and various tissue engineering techniques.

키워드

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피인용 문헌

  1. Platelet rich fibrin - a novel acumen into regenerative endodontic therapy vol.39, pp.1, 2014, https://doi.org/10.5395/rde.2014.39.1.1