YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Effects of Hot Water Extract of Chaga Mushroom on the Proliferation and Cytokines Production of Mouse Splenocytes In Vitro

차가버섯 열수 추출물이 비장세포 증식능과 Cytokine 생성능에 미치는 영향

  • Kim, Po-Ra (College of Pharmacy, Sookmyung Women's University) ;
  • Ko, Suk-Kyung (College of Pharmacy, Sookmyung Women's University) ;
  • Pyo, Myoung-Yun (College of Pharmacy, Sookmyung Women's University)
  • 김보라 (숙명여자대학교 약학대학) ;
  • 고숙경 (숙명여자대학교 약학대학) ;
  • 표명윤 (숙명여자대학교 약학대학)
  • Received : 2010.02.08
  • Accepted : 2010.05.10
  • Published : 2010.06.30
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Abstract

Chaga mushroom (Inonotus obliquus) has been identified to have various biological activities. This study was performed to investigate the potential of chaga mushroom as a immunomodulating functional food. When mouse splenocytes were exposed to various concentration of hot water extracts of chaga mushroom (IOE) with mitogens (Con A, LPS), splenocytes proliferation was significantly increased. Also, IFN-$\gamma$ and IL-4 levels were significantly enhanced. Therefore, our results suggest that chaga mushroom may have the potential of being an immunomodulating functional food.

Keywords

References

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