The Serial Change Analysis of Heart Rate According to Expiration-to-inspiration Time Ratio in Adults

호흡패턴에 따른 성인의 심박수 동태 해석

  • Park, Young-Bae (Biofunctional Medicine & Diagnostics, College of Oriental Medicine, Kyunghee University) ;
  • Han, Kyung-Sook (Biofunctional Medicine & Diagnostics, College of Oriental Medicine, Kyunghee University) ;
  • Nam, Tong-Hyun (Biofunctional Medicine & Diagnostics, College of Oriental Medicine, Sangji University)
  • 박영배 (경희대학교 한의과대학 진단.생기능의학교실) ;
  • 한경숙 (경희대학교 한의과대학 진단.생기능의학교실) ;
  • 남동현 (상지대학교 한의과대학 진단.생기능의학교실)
  • Received : 2010.07.01
  • Accepted : 2010.08.11
  • Published : 2010.08.31

Abstract

Objectives : This study aims to evaluate the effects of expiration-to-inspiration time ratio (E/I-ratio) on heart rate, which represents cardiac autonomic function, and cold-heat in the healthy people. Methods : 49 healthy young volunteers(male : female = 32 : 17) were recruited in the study. The participants completed the questionnaire for yin-yang pattern identification and then we measured the chest plethysmogram for respiration signal and the electrocardiogram for NN intervals during different E/I-ratio from 1 to 2. We compared heart rate variability including RMS-SD, VLF, LF and HF, and the trend-cycle factors decomposed from NN interval data by time series analysis among the respective E/I-ratio. We also confirmed the difference on the trend-cycle factors according to the score of the questionnaire for cold and heat pattern identification. Results : There were differences on the trend-cycle factors from NN interval data, but no significant difference on heart rate variability, among the respective E/I-ratio. We also found significant relationship between the trend-cycle factors and the heat pattern identification scores. Conclusions : The results indicate that cardiac autonomic function can be modulated by the E/I-ratio and the modulation will be slower and more tendencious than respiratory sinus arrhythmia.

Keywords

References

  1. Peng CK, Henry IC, Mietus JE, Hausdorff JM, Khalsa G, Benson H, Goldberger AL. Heart rate dynamics during three forms of meditation. Int J Cardiol. 2004 : 95(1) : 19-27. https://doi.org/10.1016/j.ijcard.2003.02.006
  2. Nitzan M, Faib I, Friedman H. Respiration induced changes in tissue blood volume distal to occluded artery, measured by photoplethysmography. J Biomed Opt. 2006 :11(4) : 040506. https://doi.org/10.1117/1.2236285
  3. Badawi K, Wallace RK, Orme-Johnson D, Rouzere AM. Electrophysiologic Characteristics of Respiratory Suspension Periods Occurring During the Practice of the Transcendental Meditation Program. Psychosom Med. 1984 : 46(3) : 267-276. https://doi.org/10.1097/00006842-198405000-00008
  4. 박찬웅. 자율신경약리학. 1판. 서울:서울대학교출판사, 1990 : 8.
  5. Lichtwarck-Aschoff M, Markstrom AM, Hedlund AJ, Nielsen JB, Nordgren KA, Sjöstrand UH. Oxygenation remains unaffected by increased inspiration - to - expiration ratio but impairs hemodynamics in surfactant-depleted piglets. Intensive Care Med. 1996 : 22(4) : 329-335. https://doi.org/10.1007/BF01700455
  6. Strauss-Blasche G, Moser M, Voica M, McLeod DR, Klammer N, Marktl W. Relative timing of inspiration and expiration affects respiratory sinus arrhythmia. Clin Exp Pharmacol Physiol. 2000 : 27(8) : 601-606. https://doi.org/10.1046/j.1440-1681.2000.03306.x
  7. Eckberg DL. Human sinus arrhythmia as an index of vagal cardiac outflow. J Appl Physiol. 1983 : 54(4) : 961-966. https://doi.org/10.1152/jappl.1983.54.4.961
  8. 일본자율신경학회. 김영설, 박영배 옮김. 자율신경기능진단. 1판. 서울:군자출판사, 2007 :87, 91-92.
  9. Heart rate variability. Task Force of The European Society of Cardiology and The North American Society of Pacing and Electrophysiology. Eur Heart J. 1996 : 17(3) : 354-381. https://doi.org/10.1093/oxfordjournals.eurheartj.a014868
  10. 노형진. SPSS/Excel에 의한 재미있는 시계열분석. 1판. 서울:효산출판사, 2008 : 2-3.
  11. 이은상. 식스시그마를 위한 통계 소프트웨어 비교분석. 서울. 한양대학교 산업경영대학원, 공학석사, 2008 : 33.
  12. Jerath R, Edry JW, Barnes VA, Jerath V. Physiology of long pranayamic breathing : neural respiratory elements may provide a mechanism that explains how slow deep breathing shifts the autonomic nervous system. Med Hypotheses. 2006 : 67(3) : 566- 571. https://doi.org/10.1016/j.mehy.2006.02.042
  13. Matsumoto S, Ikeda M, Nishikawa T, Tanimoto T, Yoshida S, Saiki C. Inhibitory mechanism of slowly adapting pulmonary stretch receptors after release from hyperinflation in anesthetized rabbits. Life Sci, 2000 : 67(12) : 1423-1433. https://doi.org/10.1016/S0024-3205(00)00738-4
  14. Schelegle E, GreenSchelegle J. An overview of the anatomy and physiology of slowly adapting pulmonary stretch receptors. Respir Physiol, 2001 : 125(1–2) : 17–31. https://doi.org/10.1016/S0034-5687(00)00202-4
  15. Kamkin A, Kiseleva I, Lozinsky I, Scholz H. Electrical interaction of mechanosensitive fibroblasts and myocytes in the heart. Basic Res Cardiol. 2005 : 100(4) : 337–345. https://doi.org/10.1007/s00395-005-0529-4
  16. Roberts L, Greene J. Hyperpolarization– activated current(Ih) : a characterization of subicular neurons in brain slices from socially and individually housed rats. Brain Res. 2005 : 1040(1–2) : 1–13. https://doi.org/10.1016/j.brainres.2004.11.065
  17. Benson H, Beary JF, Carol MP. The relaxation response. Psychiatry. 1974 : 37(1) : 37-46. https://doi.org/10.1080/00332747.1974.11023785
  18. Cuttle MF, Rusznák Z, Wong AY, Owens S, Forsythe ID. Modulation of a presynaptic hyperpolarization - activated cationic current(Ih) at an excitatory synaptic terminal in the rat auditory brainstem. J Physiol. 2001 : 534(Pt 3) : 733–744. https://doi.org/10.1111/j.1469-7793.2001.00733.x
  19. Coy KM, Imperi G, Lambert CR, Pepine CJ. Application of time series analysis to circadian rhythms : effect of beta-adrenergic blockade upon heart rate and transient myocardial ischemia. Am J Cardiol. 1990 : 66(16) : 22-24. https://doi.org/10.1016/0002-9149(90)90389-I
  20. Yoshida Y, Yokoyama K, Ishii N. Realtime continuous estimation of respiratory frequency during sleep based on heart rate time series. Conf Proc IEEE Eng Med Biol Soc. 2007 : 648-651.
  21. Billman GE, Hoskins RS. Time-series analysis of heart rate variability during submaximal exercise. Evidence for reduced cardiac vagal tone in animals susceptible to ventricular fibrillation. Circulation. 1989 : 80(1) : 146-157. https://doi.org/10.1161/01.CIR.80.1.146
  22. Lambert CR, Coy K, Imperi G, Pepine CJ. Influence of beta-adrenergic blockade defined by time series analysis on circadian variation of heart rate and ambulatory myocardial ischemia. Am J Cardiol. 1989 : 64(14) : 835-839. https://doi.org/10.1016/0002-9149(89)90827-8
  23. Halberg F, Cornélissen G, Schwartzkopff O, Syutkina EV, Grigoriev AE, Mitish MD, Yatsyk GV, Studenikin MY, Gubin D, Gubin G, Siegelova J, Fiser B, Dusek J, Homolka P, Watanabe Y, Otsuka K, Perfetto F, Tarquini R, Delmore P. Spin-offs from blood pressure and heart rate studies for health care and space research. In Vivo. 1999 : 13(1) : 67-76.