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신이식 전 예방적 혈장교환술과 사이클로스포린을 이용한 재발성 국소 분절성 사구체 경화증의 효과적인 예방 2례

Prevention of Recurrent FSGS with Cyclosporine and Plasmapheresis Prior to Renal Transplantation

  • 양은애 (경북대학교 의학전문대학원 소아과학교실) ;
  • 박효민 (경북대학교 의학전문대학원 소아과학교실) ;
  • 조민현 (경북대학교 의학전문대학원 소아과학교실) ;
  • 고철우 (경북대학교 의학전문대학원 소아과학교실) ;
  • 김형기 (경북대학교 의학전문대학원 외과학교실) ;
  • 허승 (경북대학교 의학전문대학원 외과학교실)
  • Yang, Eun-Ae (Department of Pediatrics, Kyungpook National University School of Medicine, Daegu, Republic of Korea) ;
  • Park, Hyo-Min (Department of Pediatrics, Kyungpook National University School of Medicine, Daegu, Republic of Korea) ;
  • Cho, Min-Hyun (Department of Pediatrics, Kyungpook National University School of Medicine, Daegu, Republic of Korea) ;
  • Ko, Cheol-Woo (Department of Pediatrics, Kyungpook National University School of Medicine, Daegu, Republic of Korea) ;
  • Kim, Hyung-Kee (Department of Surgery, Kyungpook National University School of Medicine, Daegu, Republic of Korea) ;
  • Huh, Seung (Department of Surgery, Kyungpook National University School of Medicine, Daegu, Republic of Korea)
  • 투고 : 2010.03.10
  • 심사 : 2010.03.29
  • 발행 : 2010.04.30

초록

국소 분절성 사구체 경화증은 소아 말기 신부전의 중요한 원인이며, 신이식 후에도 재발되는 특징을 보이는데, 이러한 재발에 대한 치료로는 혈장교환술과 사이클로스포린과 같은 면역억제제의 투여 등이 있다. 이에 저자들은 신이식 전 혈장교환술과 예방적 사이클로스포린을 투여하여 국소 분절성 사구체 경화증의 재발을 효과적으로 예방한 경험 2례를 보고하는 바이다.

We report on two children with a high risk of recurrent focal segmental glomerulosclerosis (FSGS) after renal transplantation that could be effectively prevented by prophylactic administration of cyclosporine combined with preemptive plasmapheresis prior to renal transplantation.

키워드

참고문헌

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