Annals of Clinical Neurophysiology

The Korean Society of Clinical Neurophysiology (대한임상신경생리학회)
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Correlation between Head-Up Tilt Test and Spontaneous Baroreflex Sensitivity in a Supine Position on the Diagnosis of Orthostatic Hypotension

기립성 저혈압 진단에 있어 기립경사검사와 누운 자세에서 측정한 자발성 압수용기반사 민감도의 상관관계

  • Ha, Eun-Ok (Department of Neurology, Gyeongsang National University School of Medicine) ;
  • Kim, Young-Soo (Department of Neurology, Gyeongsang National University School of Medicine) ;
  • Park, Ki-Jong (Department of Neurology, Gyeongsang National University School of Medicine) ;
  • Kim, Soo-Kyoung (Department of Neurology, Gyeongsang National University School of Medicine) ;
  • Kang, Hee-Young (Department of Neurology, Gyeongsang National University School of Medicine) ;
  • Choi, Nack-Cheon (Department of Neurology, Gyeongsang National University School of Medicine) ;
  • Kwon, Oh-Young (Department of Neurology, Gyeongsang National University School of Medicine) ;
  • Lim, Byeong-Hoon (Department of Neurology, Gyeongsang National University School of Medicine) ;
  • Yoo, Nam-Tae (Department of Neurology, Changwon Samsung Hospital, Sungkyunkwan University School of Medicine)
  • 하은옥 (경상대학교 의학전문대학원 신경과학교실) ;
  • 김영수 (경상대학교 의학전문대학원 신경과학교실) ;
  • 박기종 (경상대학교 의학전문대학원 신경과학교실) ;
  • 김수경 (경상대학교 의학전문대학원 신경과학교실) ;
  • 강희영 (경상대학교 의학전문대학원 신경과학교실) ;
  • 최낙천 (경상대학교 의학전문대학원 신경과학교실) ;
  • 권오영 (경상대학교 의학전문대학원 신경과학교실) ;
  • 임병훈 (경상대학교 의학전문대학원 신경과학교실) ;
  • 유남태 (성균관대학교 의과대학 창원삼성병원 신경과)
  • Received : 2010.08.09
  • Accepted : 2010.12.01
  • Published : 2010.12.31
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Abstract

Background: Orthostatic hypotension (OH) refers to a fall in systolic blood pressure (BP) of 20 mmHg or more, or in diastolic BP of 10 mm Hg or more within 3 minutes of standing up. The head-up tilt test (HUT) is the most useful, but potentially invasive test for the diagnosis of OH. The purpose of this study was to identify the usefulness of spontaneous baroreflex sensitivity (sBRS). Methods: Ninety one patients with orthostatic intolerance, in whom the HUT data were available, were included in the study. Patients were classified into HUT-positive (group I) and HUT-negative (group II) group. Twenty five healthy volunteers served as normal controls, and were designated as group III. In all subjects, beat-to-beat BP and heart rate were recorded using BeatScope 1.1a. We collected the 50 sBRS data in each patient in a supine position. The average value of one to ten of 50 sBRS data was defined as sBRS10, one to twenty as sBRS20, one to thirty as sBRS 30, one to forty as sBRS 40, and one to fifty as sBRS 50. Differences in sBRS10 and sBRS50 levels were statistically analyzed and compared between groups I, II, and III. Results: No significant difference in the sBRS50 level was found between Groups II and III. sBRS50 was significantly lower in Group I than in Groups II and III (p<0.05), and the same pattern of differences was observed for sBRS40, sBRS30, sBRS20, and sBRS10. Conclusions: Patients with OH showed significantly lower sBRS levels than HUT-negative patients or normal controls. Our study implies that a supine-position sBRS would provide additional diagnostic information for OH.

Keywords

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