Correlation between Serum Lipid Level and Neurophysiological Findings in Patients with Carpal Tunnel Syndrome

손목굴증후군 환자의 신경생리학적 소견과 혈청 지질 수치와의 상관관계

  • Yeo, Seung-Hyeon (Department of Neurology, Ajou University School of Medicine) ;
  • Kim, Dong-Hoon (Department of Neurology, Ajou University School of Medicine) ;
  • Sohn, Sung-Yeon (Department of Neurology, Ajou University School of Medicine) ;
  • Hong, Yoon-Hee (Department of Neurology, Ajou University School of Medicine) ;
  • Park, Jae-Bum (Department of Occupational and Environmental Medicine, Ajou University School of Medicine) ;
  • Joo, In-Soo (Department of Neurology, Ajou University School of Medicine)
  • 여승현 (아주대학교 의과대학 신경과학교실) ;
  • 김동훈 (아주대학교 의과대학 신경과학교실) ;
  • 손성연 (아주대학교 의과대학 신경과학교실) ;
  • 홍윤희 (아주대학교 의과대학 신경과학교실) ;
  • 박재범 (아주대학교 의과대학 산업의학과학교실) ;
  • 주인수 (아주대학교 의과대학 신경과학교실)
  • Received : 2010.03.08
  • Accepted : 2010.08.30
  • Published : 2010.12.31

Abstract

Background: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy caused by compression of the median nerve beneath the transverse carpal ligament. CTS can be correctly diagnosed by the patients' description of symptoms and electrophysiological tests that measure nerve conduction through the wrist. Many previous studies reported various risk factors of CTS, such as obesity, diabetes mellitus, thyroid disease and trauma. Obesity is associated with both hyperlipidemia and CTS. This study focused on the relationship between severity of CTS and serum lipid level. Methods: One hundred fourteen patients with CTS and 74 controls were divided into four groups according to the severity; normal, mild, moderate and severe. And then serum total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL-C) and high-density lipoprotein (HDL-C) were measured in each group. Results: There was a positive correlation between TG and CTS severity (p<0.001). But TC, LDL-C and HDL-C were not correlated with CTS severity. Conclusions: These results suggest that high serum TG may act as an aggravating factor of CTS.

Keywords

References

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