참고문헌
- Lee, J.E., Kim, H.J., Choi, E.K., Chai, H.Y., Yun, Y.W., Kim, D.J., et al. Four-week repeated-dose toxicity study on Pinellia Extract. The korean journal of laboratory animal science. 19: 127-141, 2003.
- 장인규, 홍남두. 죽력 (竹瀝)의 독성시험 및 약효학적 연구. 대한한방내과학회지 2: 83-101, 1985.
- Theoharides, T.C. Sudden death of a healthy college student related to ephedrine toxicity from a mahuang-containing drink. J Clin Psychopharmacol. 17: 437-439, 1997. https://doi.org/10.1097/00004714-199710000-00025
- Ali, B.H., Blunden, G. Pharmacological and toxicological properties of Nigella sativa. Phytother Res. 17: 299-305, 2003. https://doi.org/10.1002/ptr.1309
- Chen, J., Tong, Y., Zhang, X., Tian, H., Chang, Z. Acute toxicity of Stephania cepharantha. Zhong Yao Cai. 22: 468-469, 1999.
- Kitts, D., Hu, C. Efficacy and safety of ginseng. Public Health Nutr. 3: 473-485, 2000.
- 이혜정. 종류별 인삼수침엑기스의 독성 연구. 대한침구학회, 10: 167-173, 1993.
- Chen, H., Feng, R., Guo, Y., Sun, L., Zhou, Y., Jiang, J. Toxicity studies of Rhizoma Polygonati Odorati. J Ethnopharmacol. 74: 221-224, 2001. https://doi.org/10.1016/S0378-8741(00)00358-5
- 황석연, 권 운, 채희열, 조영민, 류재면, 이남진 외 6인. 상엽의 4주 반복투여독성 평가. The korean journal of laboratory animal science. 20(3):274-282, 2004.
- Ninomiya, H., Kato, S., Okuda, H. Effects of Hachimi-jio-gan in aged rats. J Altern Complement Med. 7: 355-359, 2001. https://doi.org/10.1089/107555301750463233
- Ryu, J.C., Kim, K.R., Kim, H.J., Youn, J.Y., Myung, S.W., Kim, G.H., Lee, M.J., Chang, I.M. Genotoxicity study of bojungchisup-tang, an oriental herbal decoction-in vitro chromosome aberration assay in Chinese hamster lung cells and in vivo supravital-staining micronucleus assay with mouse peripheral reticulocytes. Arch Pharm Res. 21: 391-397, 1998. https://doi.org/10.1007/BF02974632
- 황석연, 권 운, 채희열, 조영민, 류재면, 김동규 외 6인. 加味歸脾湯의 4주 반복투여독성 평가. The korean journal of laboratory animal science. 20(3):267-273, 2004.
- 배열철, 최빈혜, 김동우, 허진일, 변준석, 김대준. 補中益氣湯合大七氣湯 추출물의 ICR 마우스에서 경구단회투여 독성 평가. 대한한방내과학회, 26(2):369-378, 2005.
- 정우식, 전귀옥, 조동희, 서영호, 박미연, 최해윤, 김종대. 麻黃潤肺湯추출물의 수컷 ICR마우스에서 경구 단회투여 독성평가. 동의생리병리학회지 20(2):442-448, 2006.
- 전귀옥, 조동희, 서영호, 박미연, 최해윤, 김종대. 麻黃潤肺湯추출물의 수컷 SD Rats에서 경구 단회투여 독성평가. 대한한방내과학회지 27(1):102-113, 2006.
- 박미연. 麻黃潤肺湯 추출물의 SD계 Rats에 28일 경구 반복투여 독성실험. 대구한의대학교, 박사학위 논문, 2006.
- Jeng-Yim, S., Mee-Yepn, P., Tae-Young, J., Hae-Yun, C., Jong-Dae, K., Hyeung-Sik, L., et al. Genotoxicity testing of aqueous extracts of Mahwangypunpae-tang, a polyherbal formula. Food and Chemical Toxicology. 46: 3827-3831, 2008. https://doi.org/10.1016/j.fct.2008.10.005
- 장중경. 中景全書. 서울, 한림사, p 245, 251, 1975.
- 한의과 대학 방제학 교수 편저. 방제학. 영림사, 서울, p 99, 1995.
- 郭子光. 傷寒論湯證新編. 上海, 上海科學技術出版社, pp 84-88, 1983.
- 李梴. 원본 한의학입문. 서울, 대성문화사, pp 29-30, 59-61, 234-236, 1990.
- 朴憲在. 상한론개론. 서울, 약업신문사출판국, pp 190-191, 1991.
- 김동현, 김형민, 류종훈, 엄재영, 김상찬, 양재하 외 3명. 한방약리학. 서울, 신일상사, p 268, 298, 430, 2006.
- 장재호, 김세길. 麻黃附子細辛湯이 실험동물의 심혈관계에 미치는 영향. 원광의학, 5: 331-349, 1995.
- 고광석, 최성훈, 안규석, 문준전. 麻黃附子細辛湯 및 처방구성 약재가 Endotoxin으로 유발된 혈전증에 미치는 영향. 동의병리학회지 5: 1-14, 1990.
- 식품의약품안전청. 의약품 등의 독성시험기준. 서울: 식품의약품안전청 고시 제 2005-60호, 2005.
- Organization for Economic Co-Operation and Development (Ed.). OECD guideline (401) for testing of chemicals, acute oral toxicity (deleted 2002). 1987.
- Organization for Economic Co-Operation and Development (Ed.). OECD guideline (423) for testing of chemicals-acute oral toxicity-acute toxic class method. 2001.
- Irwin, S. Comprehensive observational assessment: Ia. A systematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse. Psychopharmacologia. 13: 222-257, 1968. https://doi.org/10.1007/BF00401402
- Dourish, C.T. Effects of drugs on spontaneous motor activity. In: Experimental Psychopharmacology. Greenshaw AJ. and Dourish, CT. (Eds). Clifton, Humana Press pp 325-334, 1987.
- Organization for Economic C0-Operation and Development (Ed.). Guideline for the testing of Chemicals TG NO. 474 Mammalian Erythrocyte Micronucleus Test, July 21, 1997.
- Schimid, W. The Micronucleus Test. Mutat. Res. 31: 9-15, 1975. https://doi.org/10.1016/0165-1161(75)90058-8
- Heddle, J.A., Stuart, E., Salamone, M.F. The Bone Marrow Micronucleus Test. In: Handbook of Mutagenicity Test Procedures (Kilbey, B.J., Legator, M., Nichols, W., Ramel, C., Eds). 2nd Edition, Elsevier. pp 441-457, 1984.
- 식품의약품안전청. 건강기능식품의 기능성 평사 체계 구축에 대한 연구. 서울, 경희대학교 약학대학, 2002.
- 식품의약품안전청. 기능성 식품의 합리적 관리체계 구축을 위한 연구. 서울, 식품의약품안전청, 2002.
- 박해모, 장인수, 이선동. 국내에서 보고된 한약 및 민간요법, 건강식품 관련 약인성 간손상에 대한 체계적 고찰. 대한한의학회지 26(2):152-165, 2005.
- Mersch-Sundermann, V., Kassie, F., Bohmer, S., Lu, W.Q., Wohlfahrth, R., Sobel, R., et al. Extract of Toxicodendron quercifolium caused genotoxicity and antigenotoxicity in bone marrow cells of CD1 mice. Food Chem Toxicol. 42: 1611-1617, 2004. https://doi.org/10.1016/j.fct.2004.05.006
- Carvalho, M.C., Barca, F.N., Agnez-Lima, L.F., de Medeiros, S.R. Evaluation of mutagenic activity in an extract of pepper tree stem bark (Schinus terebinthifolius Raddi). Environ Mol Mutagen. 42: 185-191, 2003. https://doi.org/10.1002/em.10183
- Sousa, N.C., de Carvalho, S., Spano, M.A., Graf, U. Absence of genotoxicity of a phytotherapeutic extract from Stryphnodendron adstringens (Mart.) Coville in somatic and germ cells of Drosophila melanogaster. Environ Mol Mutagen. 41: 293-299, 2003. https://doi.org/10.1002/em.10151
- 황희정. 補中益氣合大七氣湯 추출물의 유전독성 평가. 대구한의대학교 대학원 박사학위 논문, 2005.
- 함연호, 육홍선, 조성기. Ames test를 이용한 감마선 조사 黃芪, 甘草 및 陳皮의 유전독성학적 안전성 평가. 한국식품영양과학회지 8(1):54-59, 2001.
- 조성기, 육홍선, 변명우. 감마선 조사 紅蔘의 안전성에 관한 유전독성학적 연구. 한국식품영양과학회지 25(3):491-496, 1996.
- 박혜란, 함연호, 정우희. 감마선 조사 黃芪, 白朮 및 升麻 열수 추출물의 in vitro 유전독성학적 안전성 평가. 한국식품영양과학회지 31(5):910-916, 2002.
- 유영법, 조성기. 감마선 조사 當歸의 유효성분 안정성 및 유전독성학적 안전성 연구. 한국식품영양과학회지 7(1):300-306, 2000.
- Klein, H.O., Kreysch, H.G., Coerper, C., Voigt, P., Ruff, I. Preclinical and early clinical trial with mafosfamide as immune modulator. Mrthods Find Exp. Clin. Pharmacol. 9: 627-640, 1987.
- Iqbal, M.P., Sultana, F., Mehboobali, N., Pervez, S. Folinic acid protects against suppression of growth by methotrexate in mice. Biopharm Drug Dispos. 22: 169-178, 2001. https://doi.org/10.1002/bdd.271
- Banks, W.J. Female reproductive system. In: Banks WJ (Ed). Applied veterinary histology, 2nd ed. Williams & Wilkins:Baltimore. pp 506-526, 1986.
- Pineda, M.H. Female reproductive system. In: McDonald LE and Pineda MH (Eds). Veterinary endocrinology and reproduction, Lea & Febiger: Philadelphia. pp 303-354, 1989.
- Plata, E.J., Murphy, W.H.. Growth and hematologic properties of the BALB/wm strain of inbred mice. Lab Anim Sci. 22: 712-720, 1972.
- Yamaguchi, C., Fujita, S., Obara, T., Ueda, T. Effects of room temperature on reproduction, body weight and organ weights, food and water intakes, and hematology in mice. Exp Anim. 32: 1-11, 1983. https://doi.org/10.1538/expanim1978.32.1_1
-
Lee, J.H., Yang, K.J., Shin, H.D., Park, B.R., Son, C.W., Jang, H.J., et al. Single subcutaneous dose toxicity of Polycan
$^{\circledR}$ , a$\beta$ -glucan originated from Aureobasidium in mice. Lab. Anim. Res. 21: 299-305, 2005. - Lee, H.S., Lee, I.G., Ku, S.K. Single oral dose toxicity study of water extracts of Picrorrhiza Rhizoma in mice. J Toxicol Pub Health. 22: 117-126, 2006.
- US Environmental Protection Agency. Health Effects Test Guidelines OPPTS 870.100, Acute Toxicity Testing Background. US EPA August, Washington, USA. 1998.
- Renner, H.W. In vivo effects of single or combined dietary antimutagens on mutagen-induced chromosomal aberrations. Mutat Res. 244: 185-188, 1990. https://doi.org/10.1016/0165-7992(90)90070-Z
- Angulo, I., Las Heras, F.G., Garcia-Bustos, J.F., Gargallo, D., Munoz-Fernandez, M.A., Fresno, M. Nitric oxide-producing CD11b(+)Ly-6G(Gr-1)(+)CD31(ER-MP12)(+) cells in the spleen of cyclophosphamide-treated mice: implications for T-cell responses in immunosuppressed mice. Blood. 95: 212-220, 2000.
- Miyauchi, A., Hiramine, C., Tanaka, S., Hojo, K. Differential effects of a single dose of cyclophosphamide on T cell subsets of the thymus and spleen in mice: flow cytofluorometry analysis. Tohoku J Exp Med. 162: 147-167, 1990. https://doi.org/10.1620/tjem.162.147
- El-Bayoumy, K. The protective role of selenium on genetic damage and on cancer. Mutat. Res. 475: 123-139, 2001. https://doi.org/10.1016/S0027-5107(01)00075-6
-
Lee, H.S., Cho, H.R., Yang, K.J., Moon, S.B., Park, B.R., Shin, H.D., et al. Micronucleus test of polycanTM,
$\beta$ -glucan originated from Aureobsidium, in bone marrow cells of male ICR mice. Toxicol Res. 24: 11-15, 2008. https://doi.org/10.5487/TR.2008.24.1.011