생명과학회지 (Journal of Life Science)

  • 제20권5호
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  • Pages.794-798
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  • 2010
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  • 1225-9918(pISSN)
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  • 2287-3406(eISSN)
한국생명과학회 (Korean Society of Life Science)
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감물염색 직물의 추출물에 의한 항알러지 활성의 분석

Analysis of Anti-Allergic Activities by Extracts from Persimmon Sap-Stained Rayon and Cotton Fabrics

  • 이상한 (경북대학교 식품생물산업연구소 및 대학원 식품공학과)
  • Lee, Sang-Han (Food & Bio-Industry Research Institute, and Department of Food Science & Biotechnology, Kyungpook National University)
  • 투고 : 2010.02.01
  • 심사 : 2010.03.16
  • 발행 : 2010.05.31
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초록

알러지성 피부염은 현재 영유아 4인 중 1명이 발병할 정도로 심각한 질환으로 보고되어 있다. 본 연구는 청도감물염색을 한 직물 2종(인견과 면)의 물 추출물이 알러지성 피부염 유도 동물모델에서 피부의 표피에 면역관련의 세포의 수를 감소시킴을 H&E 염색으로 확인하였으며, 알러지성 피부염에 직접 관련이 있는 분자표적인 $CD4^+$ cell의 분포를 비교하여 본 결과, 유의성 있게 항알러지성 피부염 활성을 보유하고 있는 것을 확인하였다. MMP-2와 MMP-9의 면역조직화학적 분석을 수행한 결과, 이들의 발현도 감소함으로 감물염색에 사용된 감의 유용성분 예를 들면 폴리페놀 성분 등이 알러지성 피부염의 억제활성에 관련이 있을 것으로 추정된다.

Allergic dermatitis is one of the most prevalent diseases in young/juvenile children worldwide. In this research, extracts with persimmon sap-stained fabrics (rayon and cotton) exhibited an elevation in $CD4^+$ cell numbers. MMP-2 and MMP-9 expressions by Hematoxylin-Eosin staining and immunohistochemistry revealed that the expressions were decreased by addition of the extracts. The present results collectively suggest that the active ingredients of persimmon sap-stained fabrics play an important role in inhibition of DNFB-induced-atopic symptoms in vivo.

키워드

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피인용 문헌

  1. Dyeing of Cotton Fabrics with Persimmon Extract Powder - Focused on Dyeability and Mechanical Properties Depending on Color Characteristics - vol.22, pp.5, 2013, https://doi.org/10.5934/kjhe.2013.22.5.461
  2. Effect of Color Developing by Xenon Irradiation on Cotton Fabrics Dyed with Persimmon Extract Powder Dye vol.25, pp.1, 2013, https://doi.org/10.5764/TCF.2013.25.1.56
  3. Research and Survey Gal-ot Product in Jeju vol.16, pp.4, 2014, https://doi.org/10.5805/SFTI.2014.16.4.520