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Candida Parapsilosis Spondylodiscitis after Lumbar Discectomy

  • Cho, Kyun-Gil (Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Lee, Sun-Ho (Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Kim, Eun-Sang (Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine) ;
  • Eoh, Whan (Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine)
  • 투고 : 2009.06.16
  • 심사 : 2010.03.15
  • 발행 : 2010.04.28

초록

Candida is a relatively rare cause of spinal infections that commonly affects immunocompromised patients. A 70-year-old woman, who underwent a lumbar discectomy on L5-S1 two months earlier, was admitted to our department complaining of persistent back and leg pain. Magnetic resonance imaging showed irregular enhancing mass lesion in L5-S1 intervertebral space, suggest of pyogenic discitis with epidural abscess. The surgery was performed via retroperitoneal approach and the infected material at L5-S1 intervertebral space was removed. The histological examination of the specimen revealed chronic inflammation involving the bone and soft tissue, and a culture of the excised material was positive for Candida parapsilosis. The patient received intravenous fluconazole for 4 weeks after surgery and oral fluconazole 400 mg/day for 3 months after surgery. The patient made a full recovery with no symptoms 6 months after surgery. We present a rare case of spondylodiscitis after a lumbar discectomy due to Candida parapsilosis and discuss treatment option with a review of the literatures.

키워드

참고문헌

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  3. 2015 Infectious Diseases Society of America (IDSA) Clinical Practice Guidelines for the Diagnosis and Treatment of Native Vertebral Osteomyelitis in Adults vol.61, pp.6, 2010, https://doi.org/10.1093/cid/civ482
  4. A rare case of Candida parapsilosis osteomyelitis: a literature review and proposed treatment algorithm vol.11, pp.1, 2010, https://doi.org/10.1186/s13037-017-0146-9
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  6. Candida fracture-related infection: a systematic review vol.6, pp.7, 2021, https://doi.org/10.5194/jbji-6-321-2021