DOI QR코드

DOI QR Code

Synthesis and Biological Evaluation of 1-Cyclohexyl Substituted 3-Aminopyrrolidine Derivatives as CC Chemokine Receptor 2 (CCR2) Antagonists

  • Received : 2010.01.27
  • Accepted : 2010.05.10
  • Published : 2010.07.20

Abstract

Keywords

References

  1. Schwarz, M. K.; Wells, T. N. Nat. Rev. Drug Disc. 2002, 1, 347. https://doi.org/10.1038/nrd795
  2. Horuk, R.; Ng, H. P. Med. Res. Rev. 2000, 20, 155. https://doi.org/10.1002/(SICI)1098-1128(200003)20:2<155::AID-MED3>3.0.CO;2-G
  3. Libby, P. Nature 2002, 420, 868. https://doi.org/10.1038/nature01323
  4. Feria, M.; Diaz-Gonzalez, F. Expert Opin. Ther. Patents 2006, 16, 49. https://doi.org/10.1517/13543776.16.1.49
  5. Boer, W. I. Drug Disc. Today 2005, 10, 93. https://doi.org/10.1016/S1359-6446(04)03300-8
  6. Das, A. M.; Brodmerkel, C. M. Drug Disc. Today: Ther. Str. 2006, 3, 381. https://doi.org/10.1016/j.ddstr.2006.07.003
  7. PCT patent, WO 2004/050024.

Cited by

  1. ChemInform Abstract: Synthesis and Biological Evaluation of 1‐Cyclohexyl Substituted 3‐Aminopyrrolidine Derivatives as CC Chemokine Receptor 2 (CCR2) Antagonists. vol.41, pp.46, 2010, https://doi.org/10.1002/chin.201046101