Tuberculosis and Respiratory Diseases

  • 제69권6호
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  • Pages.411-417
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  • 2010
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  • 1738-3536(pISSN)
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  • 2005-6184(eISSN)
대한결핵및호흡기학회 (The Korean Academy of Tuberculosis and Respiratory Diseases)
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호흡기내과 의사를 위한 천식 리뷰

Asthma Year in Review

  • 김상하 (연세대학교 원주의과대학 내과학교실)
  • Kim, Sang-Ha (Department of Internal Medicine, Yonsei University Wonju College of Medicine)
  • 투고 : 2010.06.29
  • 심사 : 2010.06.29
  • 발행 : 2010.12.30
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초록

This review highlights articles pertaining to the following 5 topics: the relationship between asthma, allergic and non-allergic rhinitis; the novel asthma phenotypes using cluster analysis; the diagnostic properties of inhaled dry-powder mannitol for the diagnosis of asthma; the value of mepolizumab therapy in exacerbations of refractory eosinophilic asthma; the role of bronchial thermoplasty in the treatment of severe asthma.

키워드

참고문헌

  1. Shaaban R, Zureik M, Soussan D, Neukirch C, Heinrich J, Sunyer J, et al. Rhinitis and onset of asthma: a longitudinal population-based study. Lancet 2008;372:1049-57. https://doi.org/10.1016/S0140-6736(08)61446-4
  2. Bousquet J, Van Cauwenberge P, Khaltaev N; Aria Workshop Group; World Health Organization. Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol 2001;108:S147-334. https://doi.org/10.1067/mai.2001.118891
  3. Guerra S, Sherrill DL, Martinez FD, Barbee RA. Rhinitis as an independent risk factor for adult-onset asthma. J Allergy Clin Immunol 2002;109:419-25. https://doi.org/10.1067/mai.2002.121701
  4. Plaschke PP, Janson C, Norrman E, Bjornsson E, Ellbjar S, Jarvholm B. Onset and remission of allergic rhinitis and asthma and the relationship with atopic sensitization and smoking. Am J Respir Crit Care Med 2000;162: 920-4. https://doi.org/10.1164/ajrccm.162.3.9912030
  5. Leynaert B, Neukirch C, Kony S, Guenegou A, Bousquet J, Aubier M, et al. Association between asthma and rhinitis according to atopic sensitization in a population- based study. J Allergy Clin Immunol 2004;113: 86-93. https://doi.org/10.1016/j.jaci.2003.10.010
  6. Moore WC, Meyers DA, Wenzel SE, Teague WG, Li H, Li X, et al. Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program. Am J Respir Crit Care Med 2010;181:315-23. https://doi.org/10.1164/rccm.200906-0896OC
  7. Moore WC, Bleecker ER, Curran-Everett D, Erzurum SC, Ameredes BT, Bacharier L, et al. Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol 2007;119:405-13. https://doi.org/10.1016/j.jaci.2006.11.639
  8. Sverrild A, Porsbjerg C, Thomsen SF, Backer V. Diagnostic properties of inhaled mannitol in the diagnosis of asthma: a population study. J Allergy Clin Immunol 2009;124:928-32. https://doi.org/10.1016/j.jaci.2009.06.028
  9. Brusasco V, Crimi E. Methacholine provocation test for diagnosis of allergic respiratory diseases. Allergy 2001; 56:1114-20. https://doi.org/10.1034/j.1398-9995.2001.00148.x
  10. de Meer G, Marks GB, Postma DS. Direct or indirect stimuli for bronchial challenge testing: what is the relevance for asthma epidemiology? Clin Exp Allergy 2004; 34:9-16. https://doi.org/10.1111/j.1365-2222.2004.01830.x
  11. Anderson SD. Provocative challenges to help diagnose and monitor asthma: exercise, methacholine, adenosine, and mannitol. Curr Opin Pulm Med 2008; 14:39-45. https://doi.org/10.1097/MCP.0b013e3282f197f6
  12. Porsbjerg C, Brannan JD, Anderson SD, Backer V. Relationship between airway responsiveness to mannitol and to methacholine and markers of airway inflammation, peak flow variability and quality of life in asthma patients. Clin Exp Allergy 2008;38:43-50.
  13. Haldar P, Brightling CE, Hargadon B, Gupta S, Monteiro W, Sousa A, et al. Mepolizumab and exacerbations of refractory eosinophilic asthma. N Engl J Med 2009;360:973-84. https://doi.org/10.1056/NEJMoa0808991
  14. Jatakanon A, Lim S, Barnes PJ. Changes in sputum eosinophils predict loss of asthma control. Am J Respir Crit Care Med 2000;161:64-72. https://doi.org/10.1164/ajrccm.161.1.9809100
  15. Deykin A, Lazarus SC, Fahy JV, Wechsler ME, Boushey HA, Chinchilli VM, et al. Sputum eosinophil counts predict asthma control after discontinuation of inhaled corticosteroids. J Allergy Clin Immunol 2005;115:720-7. https://doi.org/10.1016/j.jaci.2004.12.1129
  16. Green RH, Brightling CE, McKenna S, Hargadon B, Parker D, Bradding P, et al. Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial. Lancet 2002;360:1715-21. https://doi.org/10.1016/S0140-6736(02)11679-5
  17. Jayaram L, Pizzichini MM, Cook RJ, Boulet LP, Lemiere C, Pizzichini E, et al. Determining asthma treatment by monitoring sputum cell counts: effect on exacerbations. Eur Respir J 2006;27:483-94. https://doi.org/10.1183/09031936.06.00137704
  18. Nair P, Pizzichini MM, Kjarsgaard M, Inman MD, Efthimiadis A, Pizzichini E, et al. Mepolizumab for prednisone- dependent asthma with sputum eosinophilia. N Engl J Med 2009;360:985-93. https://doi.org/10.1056/NEJMoa0805435
  19. Castro M, Rubin AS, Laviolette M, Fiterman J, De Andrade Lima M, Shah PL, et al. Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: a multicenter, randomized, double-blind, sham-controlled clinical trial. Am J Respir Crit Care Med 2010;181:116-24. https://doi.org/10.1164/rccm.200903-0354OC
  20. Cox PG, Miller J, Mitzner W, Leff AR. Radiofrequency ablation of airway smooth muscle for sustained treatment of asthma: preliminary investigations. Eur Respir J 2004;24:659-63. https://doi.org/10.1183/09031936.04.00054604
  21. Danek CJ, Lombard CM, Dungworth DL, Cox PG, Miller JD, Biggs MJ, et al. Reduction in airway hyperresponsiveness to methacholine by the application of RF energy in dogs. J Appl Physiol 2004;97:1946-53. https://doi.org/10.1152/japplphysiol.01282.2003
  22. Pavord ID, Cox G, Thomson NC, Rubin AS, Corris PA, Niven RM, et al. Safety and efficacy of bronchial thermoplasty in symptomatic, severe asthma. Am J Respir Crit Care Med 2007;176:1185-91. https://doi.org/10.1164/rccm.200704-571OC