DOI QR코드

DOI QR Code

다발성 낭성 유두상 폐선암 1예

A Case of Papillary Adenocarcinoma Presenting with Multiple Cysts

  • 전수연 (가천의과대학교 길병원 내과학교실) ;
  • 김유진 (가천의과대학교 길병원 내과학교실) ;
  • 경선영 (가천의과대학교 길병원 내과학교실) ;
  • 안창혁 (가천의과대학교 길병원 내과학교실) ;
  • 이상표 (가천의과대학교 길병원 내과학교실) ;
  • 박정웅 (가천의과대학교 길병원 내과학교실) ;
  • 정성환 (가천의과대학교 길병원 내과학교실) ;
  • 조은경 (가천의과대학교 길병원 내과학교실) ;
  • 성연미 (가천의과대학교 길병원 영상의학교실) ;
  • 김나래 (가천의과대학교 길병원 병리학교실)
  • Chon, Su-Yeon (Department of Internal Medicine, Gil Medical Center, Gachon University of Medicine and Science) ;
  • Kim, Yu-Jin (Department of Internal Medicine, Gil Medical Center, Gachon University of Medicine and Science) ;
  • Kyung, Sun-Young (Department of Internal Medicine, Gil Medical Center, Gachon University of Medicine and Science) ;
  • An, Chang-Hyeok (Department of Internal Medicine, Gil Medical Center, Gachon University of Medicine and Science) ;
  • Lee, Sang-Pyo (Department of Internal Medicine, Gil Medical Center, Gachon University of Medicine and Science) ;
  • Park, Jeong-Woong (Department of Internal Medicine, Gil Medical Center, Gachon University of Medicine and Science) ;
  • Jeong, Sung-Hwan (Department of Internal Medicine, Gil Medical Center, Gachon University of Medicine and Science) ;
  • Cho, Eun-Kyung (Department of Internal Medicine, Gil Medical Center, Gachon University of Medicine and Science) ;
  • Sung, Yon-Mi (Department of Radiology, Gil Medical Center, Gachon University of Medicine and Science) ;
  • Kim, Na-Rae (Department of Pathology, Gil Medical Center, Gachon University of Medicine and Science)
  • 투고 : 2009.09.04
  • 심사 : 2009.10.23
  • 발행 : 2010.02.28

초록

A 23-year old woman was admitted to our hospital with hemoptysis. The chest X-ray showed reticulonodular opacity and multiple cysts throughout the entire lung field. The chest CT scan revealed numerous bilateral cysts with various sizes, some of them with thickened walls. An open lung wedge resection was performed. The resected specimen showed scattered small nodules, 0.3 to 0.6 cm in size. Microscopically, each nodule was composed of atypical glands with an occasional papillary architecture spreading to the alveolar septa, which were morphologically consistent with a papillary adenocarcinoma with a bronchioloalveolar carcinoma growth pattern. Immunochemically, the tumor cells were negative for the S-100 protein. The patient was diagnosed with an adenocarcinoma of the lung. A variety of diseases can produce or mimic multiple, thin-walled cysts in the lung. Lung cancer with multiple cysts is quite rare. Nevertheless, adenocarcinoma should be a diagnostic consideration. We report a case of a multiple cystic adenocarcinoma of the lung.

키워드

참고문헌

  1. Hansell DM, Bankier AA, MacMahon H, McLoud TC, Muller NL, Remy J. Fleischner society: glossary of terms for thoracic imaging. Radiology 2008;246:697-722. https://doi.org/10.1148/radiol.2462070712
  2. Woodring JH, Fried AM. Significance of wall thickness in solitary cavities of the lung: a follow-up study. AJR Am J Roentgenol 1983;140:473-4. https://doi.org/10.2214/ajr.140.3.473
  3. Woodring JH. Unusual radiographic manifestations of lung cancer. Radiol Clin North Am 1990;28:599-618.
  4. Chaudhuri MR. Primary pulmonary cavitating carcinomas. Thorax 1973;28:354-66. https://doi.org/10.1136/thx.28.3.354
  5. Woodring JH, Stelling CB. Adenocarcinoma of the lung: a tumor with a changing pleomorphic character. Am J Roentgenol 1983;140:657-64. https://doi.org/10.2214/ajr.140.4.657
  6. Hill CA. Bronchioloalveolar carcinoma: a review. Radiology 1984;150:15-20. https://doi.org/10.1148/radiology.150.1.6316417
  7. Dodd GD, Boyle JJ. Excavating pulmonary metastases. Am J Roentgenol Radium Ther Nucl Med 1961;85: 277-93.
  8. Ohba S, Takashima T, Hamada S, Kitagawa M. Multiple cystic cavitary alveolar-cell carcinoma. Radiology 1972; 104:65-6. https://doi.org/10.1148/104.1.65
  9. Weisbrod GL, Towers MJ, Chamberlain DW, Herman SJ, Matzinger FR. Thin-walled cystic lesions in bronchioalveolar carcinoma. Radiology 1992;185:401-5. https://doi.org/10.1148/radiology.185.2.1329140
  10. Ryu JH, Swensen SJ. Cystic and cavitary lung diseases: focal and diffuse. Mayo Clin Proc 2003;78:744-52. https://doi.org/10.4065/78.6.744
  11. Grant LA, Babar J, Griffin N. Cysts, cavities, and honeycombing in multisystem disorders: differential diagnosis and findings on thin-section CT. Clin Radiol 2009; 64:439-48. https://doi.org/10.1016/j.crad.2008.09.015
  12. Godwin JD, Webb WR, Savoca CJ, Gamsu G, Goodman PC. Multiple, thin-walled cystic lesions of the lung. AJR Am J Roentgenol 1980;135:593-604. https://doi.org/10.2214/ajr.135.3.593
  13. Mahadeva R, Stewart S, Wallwork J. Metastatic endometrial stromal sarcoma masquerading as pulmonary lymphangioleiomyomatosis. J Clin Pathol 1999;52:147-8. https://doi.org/10.1136/jcp.52.2.147