Tuberculosis and Respiratory Diseases

  • 제68권2호
  • /
  • Pages.67-73
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  • 2010
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  • 1738-3536(pISSN)
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  • 2005-6184(eISSN)
대한결핵및호흡기학회 (The Korean Academy of Tuberculosis and Respiratory Diseases)
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탄광부 진폐증 환자에 동반된 기관지 탄분섬유화증의 임상적 의의

The Clinical Significance of Bronchial Anthracofibrosis Associated with Coal Workers' Pneumoconiosis

  • 김미혜 (울산대학교 의과대학 강릉아산병원 내과학교실) ;
  • 이홍열 (울산대학교 의과대학 강릉아산병원 내과학교실) ;
  • 남기호 (울산대학교 의과대학 강릉아산병원 내과학교실) ;
  • 임재민 (울산대학교 의과대학 강릉아산병원 내과학교실) ;
  • 정복현 (울산대학교 의과대학 강릉아산병원 내과학교실) ;
  • 류대식 (울산대학교 의과대학 강릉아산병원 영상의학교실)
  • Kim, Mi-Hye (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Lee, Hong-Yeul (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Nam, Ki-Ho (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Lim, Jae-Min (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Jung, Bock-Hyun (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Ryu, Dae-Sick (Department of Radiology, Gangneung Asan Hospital, University of Ulsan College of Medicine)
  • 투고 : 2009.11.04
  • 심사 : 2010.01.11
  • 발행 : 2010.02.28
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초록

Background: In previous study, most patients with bronchial anthracofibrosis (BAF) were non-miners, and non-occupational old aged females. However, the clinical significance of BAF in patients with coal workers' pneumoconiosis (CWP) is unknown. Methods: Among patients with CWP who transferred to our hospital for an evaluation of associated pulmonary diseases, 32 patients who had undergone a bronchofibroscopy (BFS) and chest computed tomography (CT) examination were evaluated for the association of the BAF using a retrospective chart review. Results: Nine of the 32 CWP patients (28%) were complicated with BAF. Four of the 16 simple CWP patients (25%) were complicated with BAF. According to the International Labor Organization (ILO) classification by profusion, 2 out of 3 patients in category 1, 1 out of 8 patients in category 2 and 1 out of 3 patients in category 3 were complicated with BAF. Five out of 16 complicated CWP patients were complicated with BAF. Three out of 7 patients in type A and 2 out of 5 patients in type C were complicated with BAF. CWP patients with BAF had significantly greater multiple bronchial thickening and multiple mediastinal or hilar lymph node enlargement than the CWP patients without BAF. There was no difference in the other clinical features between the CWP patients with BAF and those without BAF. Conclusion: Many CWP patients were complicated with BAF. The occurrence of BAF was not associated with the severity of CWP progression. Therefore, a careful evaluation of the airway with a bronchoscopy examination and chest CT is warranted for BAF complicated CWP patients who present with respiratory symptoms and signs, even ILO class category 1 simple CWP patients.

키워드

참고문헌

  1. Jang SJ, Lee SY, Kim SC, Lee SY, Cho HS, Park KH, et al. Clinical and radiological characteristics of non-tuberculous bronchial anthracofibrosis. Tuberc Respir Dis 2007;63:139-44. https://doi.org/10.4046/trd.2007.63.2.139
  2. Lee HS, Maeng JH, Park PG, Jang JG, Park W, Ryu DS, et al. Clinical features of simple bronchial anthracofibrosis which is not associated with tuberculosis. Tuberc Respir Dis 2002;53:510-8. https://doi.org/10.4046/trd.2002.53.5.510
  3. Ryder RC, Lyons JP, Campbell H, Gough J. Bronchial mucous gland status in coal workers' pneumoconiosis. Ann N Y Acad Sci 1972;200:370-80. https://doi.org/10.1111/j.1749-6632.1972.tb40202.x
  4. Chong S, Lee KS, Chung MJ, Han J, Kwon OJ, Kim TS. Pneumoconiosis: comparison of imaging and pathologic findings. Radiographics 2006;26:59-77. https://doi.org/10.1148/rg.261055070
  5. Remy-Jardin M, Remy J, Farre I, Marquette CH. Computed tomographic evaluation of silicosis and coal workers' pneumoconiosis. Radiol Clin North Am 1992;30:1155-76.
  6. Voisin C, Macquet L, Lenoir L, Houcke M, Savinel E, Muchery-Piat G. Bronchial involvement in diverse stages of pneumoconiosis in coal miners. Bronches 1965;15:449-61.
  7. Mulliez P, Billon-Galland MA, Dansin E, Janson X, Plisson JP. Bronchial anthracosis and pulmonary mica overload. Rev Mal Respir 2003;20(2 Pt 1):267-71.
  8. Huttner H, Beyer M, Bargon J. Charcoal smoke causes bronchial anthracosis and COPD. Med Klin (Munich) 2007;102:59-63. https://doi.org/10.1007/s00063-007-1010-y
  9. International Labour Office. International classification of radiographs of pneumoconiosis. 1st ed. Geneva: International Labour Office; 2001.
  10. Ryu DS, Jung SM, Lee DH, Kim NH, Jung BH, Chung HR, et al. CT and MR findings of bronchial anthracofibrosis. J Korean Radiol Soc 2000;42:481-6. https://doi.org/10.3348/jkrs.2000.42.3.481
  11. Choi BS. Development of coalworkers' pneumoconiosis in Korea: risk factors and incidence density. Korean J Occup Environ Med 1996;8:137-52.
  12. Churg A, Brauer M. Human lung parenchyma retains PM2.5. Am J Respir Crit Care Med 1997;155:2109-11. https://doi.org/10.1164/ajrccm.155.6.9196123
  13. No TM, Kim IS, Kim SW, Park DH, Joeng JK, Ju DW, et al. The clinical investigation for determining the etiology of bronchial anthracofibrosis. Korean J Med 2003;65:665-74.
  14. Kim YJ, Jung CY, Shin HW, Lee BK. Biomass smoke induced bronchial anthracofibrosis: presenting features and clinical course. Respir Med 2009;103:757-65.
  15. Bircan HA, Bircan S, Ozturk O, Ozyurt S, Sahin U, Akkaya A. Mediastinal tuberculous lymphadenitis with anthracosis as a cause of vocal cord paralysis. Tuberk Toraks 2007;55:409-13.
  16. Kim SW, Kim IS, Park DH, No TM, Joeng JK, Jung SW, et al. The clinical significances of bronchial anthracofibrosis in the patients with endobronchial tuberculosis. Tuberc Respir Dis 2004;56:495-504. https://doi.org/10.4046/trd.2004.56.5.495
  17. Cohen RA, Patel A, Green FH. Lung disease caused by exposure to coal mine and silica dust. Semin Respir Crit Care Med 2008;29:651-61. https://doi.org/10.1055/s-0028-1101275
  18. Shin PJ, Yong SJ, Shin KC, Lee WY, Kim ST, Cha BS, et al. Clinical significance of serum PDGF-BB and IGF-1 in coal workers' pneumoconiosis. Tuberc Respir Dis 2002;52:338-45. https://doi.org/10.4046/trd.2002.52.4.338
  19. Lee JY, Yoo KH, Ahn HR, Kim SR, Lee HW, Ahn CM, et al. The role of lymphocyte compartment and cytokine in coal workers pneumoconiosis. Tuberc Respir Dis 2002;52:241-50. https://doi.org/10.4046/trd.2002.52.3.241
  20. Paterson BF, Patterson R, Grammer LC. Pathogenesis of occupational lung disease. Clin Rev Allergy 1986;4: 303-21. https://doi.org/10.1007/BF02993163
  21. Bergin CJ, Muller NL, Vedal S, Chan-Yeung M. CT in silicosis: correlation with plain films and pulmonary function tests. AJR Am J Roentgenol 1986;146:477-83. https://doi.org/10.2214/ajr.146.3.477

피인용 문헌

  1. The association between bronchial anthracofibrosis and pneumoconiosis: A retrospective cross‐sectional study vol.57, pp.2, 2010, https://doi.org/10.1539/joh.14-0177-oa