Advances in Traditional Medicine

  • 제10권2호
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  • Pages.86-89
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  • 2010
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  • 2662-4052(pISSN)
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  • 2662-4060(eISSN)
경희대학교 융합한의과학연구소 (Kyung Hee Oriental Medicine Research Center)
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Central nervous system depressant effect of two spices ajowan (Carum copticum Karst.) and bay leaves (Cinnamomum tamala T.Nees.)

  • Rahman, T. (Department of Pharmacy, Faculty of Biological Sciences, Jahangirnagar University) ;
  • Rahman, K.A. (Department of Pharmacy, Faculty of Biological Sciences, Jahangirnagar University) ;
  • Rajia, S. (Department of Pharmacy, Faculty of Biological Sciences, Jahangirnagar University) ;
  • Alamgir, M. (Pharmacy Discipline, Khulna University) ;
  • Khan, Mahmud T.H. (Department of Pharmacy, University of Science and Technology) ;
  • Choudhuri, M. Shahabuddin K. (Department of Pharmacy, Faculty of Biological Sciences, Jahangirnagar University)
  • 투고 : 2008.03.07
  • 심사 : 2010.04.15
  • 발행 : 2010.06.30
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초록

Two common Indian spices Carum copticum Karst (ajowan) and Cinnamomum tamala T.Nees. (bay leaves) has been investigated first time to report the activity on the central nervous system. Preliminary study of the hot water extract showed depressant activity on the hole board test as evidenced from the ambulation and head dipping scores. The extracts further quicken the onset and increased the duration of pentobarbital induced sleeping time.

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참고문헌

  1. Alamgir M, Choudhuri MSK, Jabbar S, Rajia S, Khan MTH. (2002) Central nervous system depressant effect of hot water extract of Ocimum sanctum L. (Labiateae). Orient. Pharm. Exp. Med. 2, 101-105. https://doi.org/10.3742/OPEM.2002.2.2.101
  2. Baliga MS, Jagetia GC, Rao SK, Babu K. (2003) Evaluation of nitric oxide scavenging activity of certain spices in vitro: A preliminary study. Nahrung Food 47, 261-264. https://doi.org/10.1002/food.200390061
  3. Boskabady M, Jandaghi HP, Kiani S, Hasanzadeh L. (2005) Antitussive effect of Carum copticum in guinea pigs. J. Ethnopharmacol. 97, 79-82. https://doi.org/10.1016/j.jep.2004.10.016
  4. Bowman W, Rand M. (1980) Textbook of Pharmacology, Second ed., Blackwell Scientific Publications, New York.
  5. Dubey NK, Yadav P, Joshi VK. (1998) Screening of some essential oils against dermatophytes. Philippine J. Sci. 127, 139-147.
  6. Duke JA, Fulton M. (2002) CRC Handbook of Medicinal Herbs, Second ed., CRC Press, Boca Raton, Florida.
  7. Ghani A. (1998) Medicinal Plants of Bangladesh-chemical constituents and uses. First ed., p.336, Asiatic Society of Bangladesh, Dhaka.
  8. Gilani AH, Jabeen HQ, Ghayur MN, Janbaz KH, Akhtar MS. (2005) Studies on the antihypertensive, antispasmodic, bronchodilator and hepatoprotective activities of the Carum copticum seed extract. J. Ethnopharmacol. 98, 127-135. https://doi.org/10.1016/j.jep.2005.01.017
  9. Hamburger M, Hostettmann K. (1991) Bioactivity in plants: the link between phytochemistry and medicine. Phytochemistry 30, 3864-3874. https://doi.org/10.1016/0031-9422(91)83425-K
  10. Katzung B. (2001) Basic and Clinical Pharmacology, 8th ed. McGraw-Hill, New York.
  11. Koslow SH, Murthy RS, Coelho GV. (1995) Decade of the Brain: U.S. Department of Health and Human Services.
  12. Lockwood GB. (2002) Production of essential oil constituents by cultured cells of Carum copticum. Flav. Fragr. J. 17, 456-458. https://doi.org/10.1002/ffj.1129
  13. Mehta RL, Zayas JF, Yang SS. (1994) Ajowan as a Source of Natural Lipid Antioxidant. J. Agric. Food Chem. 42, 1420-1422. https://doi.org/10.1021/jf00043a006
  14. Miller LG, Murray WJ. (1998) Herbal Medicinals - A Clinicians Guide. Pharmaceutical Products Press, New York.
  15. Nadkarni KM. (1976) Indian Materia Medica, Third ed., Popular Prakashan, Bombay.
  16. Semwal AD, Sharma GK, Arya SS. (1999) Factors influencing lipid autoxidation in dehydrated precooked rice and Bengal gram dhal. J. Sci. Food Agric. 79, 1733-1736. https://doi.org/10.1002/(SICI)1097-0010(199909)79:12<1733::AID-JSFA431>3.0.CO;2-4
  17. Williamson EM, Okpako DT, Evans FJ. (1996) Pharmacological Methods in Phytotherapy Research. Selection Preparation and Pharmacological Evaluation of Plant Material. England: John Willey & Sons Ltd.