A Case of Carcinosarcoma of Skin Developed on Marjolin's Ulcer

마졸린씨 궤양에서 발생한 암육종의 증례 보고

  • Moon, Yoo-Jin (Department of Plastic and Reconstructive Surgery, College of Medicine, Soonchunhyang University) ;
  • Kim, Jun-Hyuk (Department of Plastic and Reconstructive Surgery, College of Medicine, Soonchunhyang University) ;
  • Lee, Young-Man (Department of Plastic and Reconstructive Surgery, College of Medicine, Soonchunhyang University) ;
  • Oh, Mee-Hye (Department of Pathology, College of Medicine, Soonchunhyang University) ;
  • Cho, Hyun-Deuk (Department of Pathology, College of Medicine, Soonchunhyang University)
  • 문유진 (순천향대학교 의과대학 성형외과학교실) ;
  • 김준혁 (순천향대학교 의과대학 성형외과학교실) ;
  • 이영만 (순천향대학교 의과대학 성형외과학교실) ;
  • 오미혜 (순천향대학교 의과대학 임상병리학교실) ;
  • 조현득 (순천향대학교 의과대학 임상병리학교실)
  • Received : 2009.06.03
  • Accepted : 2009.10.23
  • Published : 2010.01.10

Abstract

Purpose: Carcinosarcomas are rare neoplasms in which both malignant epithelial and mesenchymal elements are identified. We have found only twenty one cases of primary cutaneous carcinosarcoma in the English language literature. Therefore it has been difficult to diagnosis because its unclear etiology and low frequency. Methods: A 31-year-old young man with a protruding mass on his ankle dorsum was examined. The tumor was $7{\times}6{\times}3\;cm$ sized and arose from a burn scar. The mass was wide excised and applied split thickness skin graft. Characteristic pathologic finding was a mixture of squamous cell carcinoma and malignant fibrous histiocytoma. Results: Three months after the operation, the patient died of multiple metastasis to the liver, lung and finally of sepsis despite adjuvant chemotherapy and adjuvant radiotherapy. Conclusion: If a metastatic cutaneous carcinosarcoma is diagnosed, wide excision is required. There should be more aggressive management to minimize the risk of recurrence. Further research into the etiology and pathophysiology of the disease and a more careful differential diagnosis may allow improvement in treatment.

Keywords

References

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