Journal of Gastric Cancer

  • 제10권4호
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  • Pages.196-205
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  • 2010
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  • 2093-582X(pISSN)
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  • 2093-5641(eISSN)
대한위암학회 (The Korean Gastric Cancer Association)
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Prognostic Significance of Preoperative Blood Transfusion in Stomach Cancer

  • Kim, Seok-Hwan (Department of Surgery, Research Institute for Medical Science, Chungnam National Universuty School of Medicine) ;
  • Lee, Sang-Il (Department of Surgery, Research Institute for Medical Science, Chungnam National Universuty School of Medicine) ;
  • Noh, Seung-Moo (Department of Surgery, Research Institute for Medical Science, Chungnam National Universuty School of Medicine)
  • 투고 : 2010.07.22
  • 심사 : 2010.10.14
  • 발행 : 2010.12.30
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초록

Purpose: We did a retrospective study to understand the prognostic effects of preoperative blood transfusions in stomach cancer surgery. Materials and Methods: Data for 1,360 patients who underwent gastrectomy for stomach cancer between 2001 and 2009 were retrospectively reviewed. We analyzed factors that affect preoperative transfusion and clinicopathologic features. We also analyzed 5-year and overall survival rates of the transfusion and non transfusion subgroups. Results: Sixty patients (4.4%) required blood transfusion within the preoperative period. The transfused group included patients who took aspirin or clopidogrel (P<0.001), with more advanced T stages (P<0.001), with more advanced nodal metastasis (P=0.00), and with more advanced stages (P=0.00) than the non transfusion group. On multivariate analysis, preoperative transfusion was a statistically significant negative influence on 5-year survival and overall survival rates (58.2% vs 79.9% (P=0.00), 58.2% vs 76.8% (P=0.00)). Applying Cox-regression analyses, blood transfusion did appear to have an effect on prognosis and on 5-year and overall survival rates. Conclusions: We found a direct negative relation between preoperative transfusion and long term prognosis in patients receiving gastric cancer surgery.

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