Clinical and Experimental Pediatrics

대한소아청소년과학회 (The Korean Pediatric Society)
권호 표지
DOI QR코드

DOI QR Code

Update on pertussis and pertussis immunization

  • Hong, Jung-Yun (Department of Pediatrics, Medical School, Jeju National University)
  • 투고 : 2010.04.09
  • 심사 : 2010.04.15
  • 발행 : 2010.05.15
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Pertussis is a highly contagious respiratory tract disease caused by $Bordetella$ $pertussis$ infection. The clinical manifestation of this infection can be severe enough to cause death. Although pertussis has been supposed to be a vaccine-preventable disease ever since the widespread vaccination of children against pertussis was started, since the 1990s, cases of pertussis and related fatalities are on the rise, especially in countries with high vaccination coverage. In Korea, there have been no deaths due to pertussis since 1990, and the vaccination rate continues to be approximately 94%. However, the number of pertussis cases reported to the Korea Center for Disease Control and Prevention has tended to increase in the 2000s, and in 2009, there was an obvious increase in the number of pertussis cases reported. This review aims to present the latest information about the pathogenesis, diagnosis, treatment, and prevention of pertussis.

키워드

참고문헌

  1. Department of Vaccines and Biologicals, World Health Organization. WHO-recommended standards for surveillance of selected vaccinepreventable diseases. Geneva: WHO, 2003: p28.
  2. Edwards KM. Overview of pertussis: focus on epidemiology, sources of infection, and long term protection after infant vaccination. Pediatr Infect Dis J 2005;24(6 Suppl):104S-108S. https://doi.org/10.1097/01.inf.0000166154.47013.47
  3. Division of Tuberculosis and Bacterial Respiratory Infections: Korea National Health Institute. The report of a survey for pertussis infection status in Korea. Seoul: Korea National Health Institute, 2007:95-110.
  4. Division of Tuberculosis and Bacterial Respiratory Infections: Korea National Health Institute. Serotypic variations of Bordetella pertussis isolated in Korea. Seoul: Korea National Health Institute, 2008:621-25
  5. Division of Tuberculosis and Bacterial Respiratory Infections: Korea National Health Institute. Increasing incidence of pertussis in Korea. Seoul: Korea National Health Institute, 2009:709
  6. Heininger M, Stehr K, Schmitt-Grohe S. Clinical characteristics of illness caused by Bordetella parapertussis compared with illness caused by Bordetella pertussis. Pediatr Infect Dis J 1994;13:306-09. https://doi.org/10.1097/00006454-199404000-00011
  7. Hewlett EL: A commentary on the pathogenesis of pertussis. Clin Infect Dis 1999;28(2 Suppl):94S-98S. https://doi.org/10.1086/515055
  8. Long SS, Welkon CJ, Clark JL. Widespread silent transmission of pertussis in families:antibody correlates of infection and symptomatology. J Infect Dis 1990;161:480-6. https://doi.org/10.1093/infdis/161.3.480
  9. Paddock CD, Sanden GN, Cherry JD, Gal AA, Langston C, Tatti KM. Pathology and pathogenesis of fatal Bordetella pertussis infection in infants. Clin Infect Dis 2008;47:328-38. https://doi.org/10.1086/589753
  10. Harnden A, Grant C, Harrison T, Perera R, Brueggemann AB, White RM, et al. Whooping cough in school age children with persistent cough: prospective cohort study in primary care. BMJ 2006;333:174-7. https://doi.org/10.1136/bmj.38870.655405.AE
  11. Ntezayabo B, De Serres G, Duval B. Pertussis resurgence in Canada largely caused by a cohort effect. Pediatr Infect Dis J 2003;22:22-7. https://doi.org/10.1097/00006454-200301000-00009
  12. Halasa NB, Barr FE, Johnson JE. Fatal pulmonary hypertension associated with pertussis in infants: does extracorporeal membrane oxygenation have a role? Pediatrics 2003;112:1274-8. https://doi.org/10.1542/peds.112.6.1274
  13. Centers for Disease Control and Prevention. Pertussis deaths - United States, 2000. MMWR 2002;51:616-8.
  14. Cantor RM, Pipas L, McCabe JB. Emergency department evaluation of etiology of pediatric cardiac arrest: the role of postmortem cultures. Pediatr Emerg Med 1990;6:221.
  15. Heininger U, Kleemann WJ, Cherry JD. For the sudden infant death syndrome study group: A controlled study of the relationship between Bordetella pertussis infections and sudden unexpected deaths among German infants. Pediatrics 2004;114:e9-e15. https://doi.org/10.1542/peds.114.1.e9
  16. Bisgard KM, Pascual FB, Ehresmann KR, Miller CA, Cianfrini C, Jennings CE, et al. Infant pertussis: who was the source? Pediatr Infect Dis J 2004;23:985-90. https://doi.org/10.1097/01.inf.0000145263.37198.2b
  17. Mikelova LK, Halperin SA, Scheifele D. Members of the Immunization Monitoring program, Active (IMPACT). Predictors of death in infants hospitalized with pertussis: a case-control study of 16 pertussis deaths in Canada. J Pediatr 2003;143:576-81. https://doi.org/10.1067/S0022-3476(03)00365-2
  18. Srugo I, Benilevi D, Madeb R. Pertussis infection in fully vaccinated children in day-care centers, Israel. Emerg Infect Dis 2000;6:526 -9. https://doi.org/10.3201/eid0605.000512
  19. Hallander HO. Microbiological and serological diagnosis serological diagnosis of pertussis. Clin Infect Dis 1999;28( 2 Suppl):99 S-106 S. https://doi.org/10.1086/515056
  20. Baughman AL, Bisgard KM, Edwards KM. Establishment of diagnostic cutoff points for levels of serum antibodies to pertussis toxin, filamentous hemagglutinin, and fimbriae in adolescents and adults in the United States. Clin Diagn Lab Immunol 2004;11:1045-53.
  21. Bergquist SO, Bernander S, Dahnsjo H. Erythromycin in the treatment of pertussis: a study of bacteriologic and clinical effects. Pediatr Infect Dis J 1987;6:458-61. https://doi.org/10.1097/00006454-198705000-00009
  22. von König CH. Use of antibiotics in the prevention and treatment of pertussis. Pediatr Infect Dis J 2005; 24(5 Suppl):66S-68S. https://doi.org/10.1097/01.inf.0000160916.47479.22
  23. Mooi FR, van Loo IHM, van Gent M, Qiushui HE, Bart MJ, Heuvelman KJ. Bordetella pertussis strains with increased toxin production associated with pertussis resurgence. Emerg Infect Dis. 2009;15:1206-12. https://doi.org/10.3201/eid1508.081511
  24. de Melker Hester E, Schellekens JFP, Neppelenbroek SE, Mooi FR, Rumke HC, Conyn-van Spaendonck MAE. Reemergence of pertussis in the highly vaccinated population of the Netherlands: observations on surveillance data. Emerg Infect Dis 2000;6:348-57. https://doi.org/10.3201/eid0604.000404
  25. Rendi-Wagnera P, Tobiasb J, Moermanc L, Gorena S, Bassald R, Greend M, et al. The seroepidemiology of Bordetella pertussis in Israel - Estimate of incidence of infection. Vaccine 2010;28:3285-90. https://doi.org/10.1016/j.vaccine.2010.02.104

피인용 문헌

  1. Three Cases of Pertussis in Infants younger than Three Months without Immunization of DTaP vol.21, pp.1, 2010, https://doi.org/10.7581/pard.2011.21.1.56
  2. Infant Pertussis and Household Transmission in Korea vol.27, pp.12, 2010, https://doi.org/10.3346/jkms.2012.27.12.1547
  3. Assessment of vaccine candidates for persons aged 50 and older: a review vol.13, pp.None, 2010, https://doi.org/10.1186/1471-2318-13-32
  4. The disease burden of pertussis in adults 50 years old and older in the United States: a retrospective study vol.13, pp.None, 2013, https://doi.org/10.1186/1471-2334-13-32
  5. Peptide sharing between Bordetella pertussis proteome and human sudden death proteins: a hypothesis for a causal link vol.8, pp.8, 2010, https://doi.org/10.2217/fmb.13.72
  6. Bordetella pertussis pathogenesis: current and future challenges vol.12, pp.4, 2010, https://doi.org/10.1038/nrmicro3235
  7. Clinical, laboratorial and radiographic predictors of Bordetella pertussis infection vol.32, pp.4, 2014, https://doi.org/10.1590/s0103-05822014000400003
  8. Cooperative Roles for Fimbria and Filamentous Hemagglutinin in Bordetella Adherence and Immune Modulation vol.6, pp.3, 2010, https://doi.org/10.1128/mbio.00500-15
  9. Pertussis Accompanying Recent Mycoplasma Infection in a 10-Year-Old Girl vol.47, pp.3, 2015, https://doi.org/10.3947/ic.2015.47.3.197
  10. Pertussis Reinfection in an Adult: A Cause of Persistent Cough Not to Be Ignored vol.2017, pp.None, 2010, https://doi.org/10.1155/2017/4786141
  11. A survey of the domestic epidemiological characteristics and clinical manifestations of pertussis vol.6, pp.1, 2010, https://doi.org/10.4168/aard.2018.6.1.54
  12. Rapid detection of respiratory organisms with the FilmArray respiratory panel in a large children’s hospital in China vol.18, pp.None, 2018, https://doi.org/10.1186/s12879-018-3429-6
  13. The problem of pertussis in some regions of the world vol.9, pp.2, 2010, https://doi.org/10.15789/2220-7619-2019-2-354-362
  14. Recombinant Production of a Novel Fusion Protein: Listeriolysin O Fragment Fused to S1 Subunit of Pertussis Toxin vol.25, pp.1, 2010, https://doi.org/10.29252/ibj.25.1.33
  15. PTX Instructs the Development of Lung-Resident Memory T Cells in Bordetella pertussis Infected Mice vol.13, pp.9, 2021, https://doi.org/10.3390/toxins13090632