Journal of Yeungnam Medical Science

영남대 의대 학술지 편집위원회 (Yeungnam University College of Medicine, Yeungnam University Institute Medical Science)
권호 표지

성인 발병성 스틸병(Adult-onset Still's disease)으로 오인된 전신홍반루푸스(Systemic Lupus Erythematosus) 1예

A Case of Systemic Lupus Erythematosus Misdiagnosed as Adult-onset Still's Disease

  • 오명진 (영남대학교 의과대학 내과학교실) ;
  • 김현제 (영남대학교 의과대학 내과학교실) ;
  • 이한솔 (영남대학교 의과대학 내과학교실) ;
  • 허지안 (영남대학교 의과대학 내과학교실) ;
  • 홍영훈 (영남대학교 의과대학 내과학교실) ;
  • 이충기 (영남대학교 의과대학 내과학교실)
  • Oh, Myung-Jin (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
  • Kim, Hyun-Je (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
  • Lee, Han-Sol (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
  • Hur, Ji-An (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
  • Hong, Young-Hoon (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
  • Lee, Choong-Ki (Department of Internal Medicine, College of Medicine, Yeungnam University)
  • 발행 : 2010.06.30
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초록

Adult-onset Still's disease (AOSD) is an inflammatory disorder that's characterized by daily, spiking high fever, arthritis and an evanescent, salmon-pink rash. AOSD is diagnosed purely on the basis of the typical clinical features of the illness. The symptoms commonly include swelling of the lymph nodes, enlargement of the spleen and liver, and a sore throat. AOSD is difficult to differentiate from systemic lupus erythematosus (SLE) due to the similar clinical manifestations. We report here on a case of a 16-year-old female patient with autism and epilepsy and who complained of daily spiking fever for 20 days. The patient had maculopapular skin rashes on the face and whole body and lymphadenopathy. The liver function tests were elevated mildly. The initial rheumatoid factor (RF) and antinuclear antibody (ANA) tests were negative. We diagnosed her as having adult-onset Still's disease according to the criteria of Yamaguchi. We successfully treated her with oral prednisolone. But her antinuclear antibody test was changed to positive after discharge. So we finally diagnosed her as having SLE.

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