Journal of Yeungnam Medical Science

Yeungnam University College of Medicine, Yeungnam University Institute Medical Science (영남대 의대 학술지 편집위원회)
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A Case of Functionary Cystic Parathyroid Adenoma with Papillary Thyroid Carcinoma

유두상 갑상선암과 동반된 기능성 낭종성 부갑상선 선종 1예

  • Chang, Woo-Jin (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
  • Jung, Hyun-Hee (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
  • Park, Sang-Hyen (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
  • Sohn, Se-Hoon (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
  • Yoon, Ji-Sung (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
  • Lee, Hyoung-Woo (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
  • Won, Kyu-Chang (Department of Internal Medicine, College of Medicine, Yeungnam University) ;
  • Cho, In-Ho (Department of Nuclear Medicine, College of Medicine, Yeungnam University)
  • 장우진 (영남대학교 의과대학 내과학교실) ;
  • 정현희 (영남대학교 의과대학 내과학교실) ;
  • 박상현 (영남대학교 의과대학 내과학교실) ;
  • 손세훈 (영남대학교 의과대학 내과학교실) ;
  • 윤지성 (영남대학교 의과대학 내과학교실) ;
  • 이형우 (영남대학교 의과대학 내과학교실) ;
  • 원규장 (영남대학교 의과대학 내과학교실) ;
  • 조인호 (영남대학교 의과대학 핵의학교실)
  • Published : 2010.12.30
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Abstract

Cystic parathyroid adenoma is one of rare causes of hyperparathyroidism, and tends to cause increased serum level of parathyroid hormone, alkaline phosphate and serum calcium level similar to when compared to those of solid adenoma. The possibility of a coincidental appearance of primary hyperparathyrodism and nonmedullary thyroid cancer is rare, and often neglected. A 40-year-old female presented with constipation and weight loss for 3 months. The serum calcium, phosphate and alkaline phosphate were 16.6 mg/dl, 2.2 mg/dl and 505 IU/L respectively and serum parathyroid hormone level was 1556.2 pg/mL. Neck US showed mixed nodules at both thyroid lobes, and PET-CT showed a right thyroid nodule without FDG uptake. The patient was diagnosed of primary hyperparathyroidism and underwent parathyroidectomy and a total thyroidectomy. Histopathologic results revealed parathyroid adenoma with cystic change (2 cm greater diameter) in the right lower parathyroid gland and coexistent papillary carcinoma of the right lobe of thyroid gland (infiltrating, 0.3 cm in greater diameter). She remained well and serum calcium, phosphate, parathyroid hormone level were normalized within 24 hours.

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