Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
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The Hemodynamic Effects of Acupuncture on Taechung($LR_3$) on Mammary Tissues of Rat Monitored by Diffuse Optical Imaging

Diffuse Optical Imaging으로 측정한 태충($LR_3$) 자침이 쥐의 유방 조직에 미치는 혈역학적 변화

  • Cho, Myeong-Rae (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Dongshin University) ;
  • Kim, Jae-Gwan (The Beckman Laser Institute, University of California)
  • 조명래 (동신대학교 한의과대학 침구학교실) ;
  • 김재관 (캘리포니아대학교 어바인캠퍼스 Beckman 레이저연구소)
  • Received : 2010.10.29
  • Accepted : 2010.12.11
  • Published : 2010.12.20
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Abstract

목적 : 태충($LR_3$)에 자침을 하는 것이 쥐의 유방 조직에 미치는 혈역학적 변화를 측정하기 위하여 diffuse optical imaging 기법을 사용하였다. 방법 : 실험에 사용한 쥐는 자침을 하지 않은 대조군 7마리, 태충에 자침을 한 실험군 8마리로 총 2개의 군으로 나누었다. 몸무게 170g 정도의 건강한 암컷 쥐는 100% 산소와 1.5% isoflurane을 혼합한 것을 이용하여 마취시켰다. 자침은 양 발등의 첫째와 둘째 중족골 사이의 지점인 태충($LR_3$)에 20분간 시행하였다. Beckman Laser Institute and Medical Clinic에서 개발된 modulated imaging system을 이용하여 자침하기 전과 자침하고 있는 동안에 산화혈색소(OHb), 탈산소혈색소(RHb), 총 혈색소(THb)와 조직 산소 포화도($StO_2$)의 영상을 얻었다. 결과 : 실험 결과 태충($LR_3$)에 자침을 한 실험군에서는 대조군에 비하여 유의성이 있는 OHb THb의 감소와 유의성이 없는 RHb의 증가가 나타났다. 결론 : Diffuse optical imaging 기법으로 자침 중에 조직 산소공급과 혈류량의 변화를 확인할 수 있었고, 이는 비침습적으로 자침의 효과를 측정하는 데 활용할 수 있다고 생각한다. 또한 자침으로 인한 유방조직의 혈역학적 조절은 암 검진뿐만 아니라 암 치료에도 다른 치료와 병행하여 활용할 수 있으리라 생각한다.

Keywords

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