DOI QR코드

DOI QR Code

The Early Detection of Recurrence of Malignant Peripheral Nerve Sheath Tumor by Frequent Magnetic Resonance Imaging

  • Lee, Chang-Sub (Departments of Neurosurgery, Jeju National University School of Medicine, Institute of Medical Science) ;
  • Huh, Ji-Soon (Departments of Neurosurgery, Jeju National University School of Medicine, Institute of Medical Science) ;
  • Chang, Jee-Won (Departments of Thoracic Surgery, Jeju National University School of Medicine, Institute of Medical Science) ;
  • Park, Ji-Kang (Departments of Radiology, Jeju National University School of Medicine, Institute of Medical Science)
  • 발행 : 2010.01.28

초록

Surgery has a key role in the treatment of malignant peripheral nerve sheath tumors (MPNSTs), but the resectability of paraspinal MPNSTs is only 20%. Therefore, spinal MPNSTs show frequent recurrence and poor prognosis. Local recurrence is much more common than metastasis for MPNSTs, and surgery still has a key role in the treatment of local recurrence. Therefore, it is important that recurrence must be detected before resectability is lost. However, no evidence-based follow-up protocol has been established for MPNST. The authors performed gross total resection in a 34-year-old woman presented with thoracic MPNST. Adjuvant radiotherapy and chemotherapy were not administered since these adjuvant therapies generally do not improve survival in MPNST and may cause additional neurovascular damage. Instead, the authors monitored the primary site every 3 months using magnetic resonance imaging to detect local recurrence at the earliest opportunity. The tumor recurred locally on two occasions without overt symptoms at 21 and 24 months postoperatively. These recurrences were treated successfully by gross total removal.

키워드

참고문헌

  1. Ducatman BS, Scheithauer BW, Piepgras DG, Reiman HM, Ilstrup DM : Malignant peripheral nerve sheath tumors. Cancer 57 : 2006-2021, 1986 https://doi.org/10.1002/1097-0142(19860515)57:10<2006::AID-CNCR2820571022>3.0.CO;2-6
  2. Gachiani J, Kim D, Nelson A, Kline D : Surgical management of malignant peripheral nerve sheath tumors. Neurosurg Focus 22 : E13, 2007
  3. Gupta G, Maniker A : Malignant peripheral nerve sheath tumors. Neurosurg Focus 22 : E12, 2007
  4. Kim JK, Song JW, Park WM, Jang JS, Rhee CH, Lee SH : Three cases of primary malignant schwannomas. J Korean Neurosurg Soc 28 : 720-725, 1999
  5. Lee DC, Kim JK, Cho KS, Kim MC : Malignant Peripheral Nerve Sheath Tumor of the Cauda Equina in Type I Neurofibromatosis: Case Report. J Korean Neurosurg Soc 33 : 105-107, 2003
  6. Lee JH, Byun YW, Yim MB, Kim IH : A Case of Malignant Schwannoma in the Sacrum. J Korean Neurosurg Soc 11 : 389-395, 1982
  7. Singh T, Kliot M : Imaging of peripheral nerve tumors. Neurosurg Focus 22 : E6, 2007
  8. Wong WW, Hirose T, Scheithauer BW, Schild SE, Gunderson LL : Malignant peripheral nerve sheath tumor : analysis of treatment outcome. Int J Radiat Oncol Biol Phys 42 : 351-360, 1998

피인용 문헌

  1. Ophthalmic Rete Mirabile: The First Angiographic Documentation of Embryonic Ophthalmic Collaterals in a Patient with Moyamoya Disease : A Case Report vol.14, pp.3, 2010, https://doi.org/10.1177/159101990801400309
  2. Favorable Outcome After Radical Resection and Subsequent Local Irradiation of Malignant Peripheral Nerve Sheath Tumor in the Cervical Spine : -Case Report- vol.52, pp.9, 2010, https://doi.org/10.2176/nmc.52.670
  3. A retroperitoneal NF1-independent malignant peripheral nerve sheath tumor with elevated serum CA125: case report and discussion vol.109, pp.1, 2010, https://doi.org/10.1007/s11060-012-0865-9
  4. RE : The Early Detection of Recurrence of Malignant Peripheral Nerve Sheath Tumor by Frequent Magnetic Resonance Imaging vol.55, pp.6, 2010, https://doi.org/10.3340/jkns.2014.55.6.387