Korean Journal of Bronchoesophagology (대한기관식도과학회지)
- Volume 16 Issue 2
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- Pages.97-104
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- 2010
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- 1226-0916(pISSN)
Update on Medical Treatment of GERD/LPR
위식도역류질환과 인후두역류질환의 약물 요법에 대한 최신지견
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Kim, Mi-Na
(Department of Internal Medicine, Liver Research Institute, Seoul National University College of Medicine) ;
- Kim, Joo-Sung (Department of Internal Medicine, Liver Research Institute, Seoul National University College of Medicine)
- Received : 2010.12.04
- Accepted : 2010.12.14
- Published : 2010.12.30
Abstract
Gastroesophageal reflux disease (GERD) is a common disorder caused by the reflux of gastric contents into the esophagus. According to the recent classification, GERD can elicit esophageal and extraesophageal syndromes. Laryngopharyngeal reflux (LPR) is defined as laryngeal symptoms with laryngeal inflammation caused by the acid reflux. The prevalence of GERD and LPR is increasing during the past decades in Korea and management of GERD and LPR is a challenging issue in clinical practice. Proton pump inhibitor is the most effective drug in the treatment of GERD. Most patients with LPR are given a 2-month trial of a proton pump inhibitor (PPI), however, there is still little evidence on the diagnosis or the treatment of LPR. During the last years concern have been raised regarding the risk of averse events related to long-term use of PPI. We review the recent update on medical treatment of GERD/LPR.