Successful Birth of Pups Produced by GnRH-induced Estrus and Natural Mating in Captive Red Fox (Vulpes vulpes)

  • 투고 : 2010.11.22
  • 심사 : 2010.12.03
  • 발행 : 2010.12.31

초록

On January 6, 2010, two months earlier than normal breeding season, a red fox vixen was implanted with synthetic GnRH analogue, Deslorelin. Blood was sampled every 2~3 days from the day of implant to identifying spermatozoa on stains of epithelial cells. Estradiol and progesterone were examined. Even though the vixen was in non-breeding season, she was mated by a male fox. Pregnancy was confirmed by canine pregnancy detection kit that detect relaxin released from placenta. Four healthy pups were born on March 9, 2010. This is the first report showing synthetic GnRH can activate ovarian function and lead to fertile estrus of red fox in non-breeding season.

키워드

참고문헌

  1. Asa CS, Bauman K, Callahan P, Bauman J, Volkmann DH and Jochle W. 2006. GnRH-agonist induction of fertile estrus with either natural mating or artificial insemination, followed by birth of pups in gray wolves (Canis lupus). Theriogenology 66:1778-1782. https://doi.org/10.1016/j.theriogenology.2006.01.035
  2. Bonnin M, Mondain-Monval M and Butourne B. 1978. Oestrogen and progesterone concentrations in peripheral blood in pregnant red foxes (Vulpes vulpes). J. Reprod. Fert. 54:37-41. https://doi.org/10.1530/jrf.0.0540037
  3. Bouchard GF, Solorzano N, Concannon PW, Youngquist RS and Bierschwal CJ. 1991. Determination of ovulation time in bitches based on teasing, vaginal cytology, and elisa for progesterone. Theriogenology 35:603-611. https://doi.org/10.1016/0093-691X(91)90456-N
  4. Braun BC, Frank A, Dehnhard M, Voigt CC, Vargas A, Goritz F and Jewgenow K. 2009. Pregnancy diagnosis in urine of Iberian lynx (Lynx pardinus). Theriogenology 71:754-761. https://doi.org/10.1016/j.theriogenology.2008.09.054
  5. Buff S, Fontbonne A, Lopez P, Rauer M and Crevat D. 2001. Circulating relaxin concentrations in pregnant and nonprcgnant bitches: Evaluation of a new enzymeimmunoassay for determination of pregnancy. J. Reprod. Fertil. Suppl. 57:187-191.
  6. Carlson DA and Gese EM. 2007. Relaxin as a diagnostic tool for pregnancy in the coyote (Canis latrans). Ani. Reprod. Sci. 101:304-312. https://doi.org/10.1016/j.anireprosci.2006.07.011
  7. Carlson DA and Gese EM. 2009. Influence of exogenous gonadotropin-releasing hormone on seasonal reproductive behavior of the coyote (Canis latrans). Theriogenology 72:773-783. https://doi.org/10.1016/j.theriogenology.2009.05.012
  8. Concannon PW, Castracane VD, Temple M and Montanez A. 2009. Endocrine control of ovarian function in dogs and other carnivores. Anim. Reprod. 6:172-193.
  9. Concannon PW. 1989. Induction of fertile oestrus in anoestrous dogs by constant infusion of GnRH agonis. J. Reprod. Fertil. Suppl. 39:149-160.
  10. Farstad W, Fougner JA and Torres CG. 1992a. The effect of sperm number on fertility in blue fox vixens (A/apex lagopus) artificially inseminated with frozen silver fox (Vulpes vulpes) semen. Theriogenology 37:699-711. https://doi.org/10.1016/0093-691X(92)90149-L
  11. Farstad W, Fougner JA and Torres CG. 1992b. The optimum time for single artificial insemination of blue fox vixens (Alapex lagopus) with frozen-thawed semen from silver foxes (Vulpes vulpes). Theriogenology 38:853-865. https://doi.org/10.1016/0093-691X(92)90161-J
  12. Hartley FG, Follett BK, Harris S, Hirst D and McNeilly AS. 1994. The endocrinology of gestation failure in foxes (Vulpes vulpes). J. Reprod. Fert. 100:341-346. https://doi.org/10.1530/jrf.0.1000341
  13. Hase M, Hori T, Kawakami E and Tsutsui T. 2000. Plasma LH and progesterone levels before and after ovulation and observation of ovarian follicles by ultrasonographic diagnosis system in dogs. J. Vet. Med. Sci. 62:243-248. https://doi.org/10.1292/jvms.62.243
  14. Kutzler MA. 2007. Estrus induction and synchronization in canids and felids. Theriogenology 68:354-374. https://doi.org/10.1016/j.theriogenology.2007.04.014
  15. McKinnon AO, Nobelius AM, del Marmol Figuersoa ST, Skidmore J, Vasey JR and Trigg TE. 1993. Predictable ovulation in mares treated with an implant of the GnRH analogue deslorelin. J. Eq. Vet. Sci. 25:321-323. https://doi.org/10.1111/j.2042-3306.1993.tb02972.x
  16. Moller OM. 1973. Progesterone concentrations in the peripheral plasma of the blue fox, Alapex lagapus, during pregnancy and the oestrous cycle. J. Endocr. 59:429-437. https://doi.org/10.1677/joe.0.0590429
  17. Park JE, Hong SG, Kang JT, Oh HJ, Kim MK, Kim MJ, Kim HJ, Kim DY, Jang G and Lee BC. 2009. Birth of viable puppies derived from breeding cloned female dogs with a cloned male. Theriogenology 72:721-730. https://doi.org/10.1016/j.theriogenology.2009.05.007
  18. Samper JC, Jensen S, Sergeant J and Estrada A. 2002. Timing of induction of ovulation in mares treated with ovuplant or chorulon. J. Eq. Vet. Sci. 22:320-323. https://doi.org/10.1016/S0737-0806(02)70080-4
  19. Sherwood OD. 1994. Relaxin. In: Knobil, E., Neil, J.D. (Eds.), The Physiology of Reproduction, 2nd ed. Raven Press, New York.
  20. Smith AJ, Mondain-Monval M, Moller OM, Scholler R and Hansson V. 1985. Seasonal variations of LH, prolactin, androstenedione, testosterone and testicular FSH binding in the male blue fox (Alopex lagopus). J. Reprod. Fert. 74:449-458. https://doi.org/10.1530/jrf.0.0740449
  21. Smith MS and McDonald LF. 1974. Serum levels of luteinizing hormone and progesterone during the estrous cycle, pseudo-pregnancy in the dog. Endocrinology 94:4.5-411.