Journal of the korean academy of Pediatric Dentistry (대한소아치과학회지)

Korean Academy of Pediatric Dentistry (대한소아치과학회)
권호 표지

REMINERALIZATION EFFECT OF SODIUM FLUORIDE VARNISH ON WHITE LESION BY APPLICATION INTERVALS

불화나트륨 바니쉬의 도포 주기에 따른 백색 병소의 재광화 효과

  • Lee, Eun-Hui (Department of Pediatric Dentistry, Dental College, Dankook University) ;
  • Kim, Jong-Soo (Department of Pediatric Dentistry, Dental College, Dankook University) ;
  • Yoo, Seung-Hoon (Department of Pediatric Dentistry, Dental College, Dankook University)
  • 이은희 (단국대학교 치과대학 소아치과학교실) ;
  • 김종수 (단국대학교 치과대학 소아치과학교실) ;
  • 유승훈 (단국대학교 치과대학 소아치과학교실)
  • Received : 2010.07.15
  • Accepted : 2010.11.11
  • Published : 2010.11.30
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Abstract

This study is about the treatment effect of fluoride varnish on white lesion. The changes in microhardness values and lesion sizes were compared and analyzed in relation to application interval, frequency, etc. Resin blocks were fabricated with the crown portion of permanent molars. Samples were classified into group I(1 week), group II(2 weeks) and group III(3 weeks) based on fluoride application intervals, each with 15 samples. Samples were soaked into a decalcifying solution for 15 days, and stored in artificial saliva at $37^{\circ}C$ thermostat. The changes in microhardness values and lesion sizes, before/after decalcification and after fluoride application, were evaluated. The following results were obtained. 1. Microhardness values in group II and III exhibited almost twice the increasing rate than group I. There were significant differences between group I and II, and group I and III (p<0.05), but none between group II and III (p>0.05). 2. Change in lesion sizes showed no significant differences between group I and II, III (p>0.05). In conclusion, fluoride varnish application results in both qualitative and quantitative improvements in white lesions. The satisfactory results can be obtained when varnish is applied at more than 2 weeks interval.

본 연구는 불소 바니쉬의 백색 병소에 대한 치료 효과를 도포 기간, 빈도 등에 따라 미세경도와 병소 면적 변화를 통해 비교 분석하였다. 실험을 위해 대구치의 치관부를 이용해 레진 블록을 제작하였다. 불소 도포 주기에 따라, 1주군(I군), 2주군(II군), 3주군(III군)으로 분류하여 군당 15개의 시편을 배정하였다. 시편은 카보폴 907을 이용한 인공우식용액에 15일간 침지하여 탈회시켰으며, 이후 인공타액에 넣어 $37^{\circ}C$ 항온기에 보관하였다. 탈회 전, 탈회 후, 불소 도포 후 미세경도와 병소 면적의 변화를 평가하였다. 연구 결과 얻은 결론은 다음과 같다. 1. 미세경도 값은 I군과 비교하여 II군과 III군에서 약 2배의 증가율이 관찰되었으며, I군과 II군, I군과 III군 사이에서 통계적 유의성을 보였으나(p<0.05), II군과 III군 사이에서는 유의성을 보이지 않았다(p>0.05). 2. 색조 측정기를 이용해 관찰한 병소 면적의 변화는 I군과 II군, III군 사이에 통계적 유의성을 보이지 않았다(p>0.05). 이상의 결과에서 불소 바니쉬 도포를 통해 백색 병소의 양적, 질적 개선을 얻을 수 있다고 생각되며, 2주 이상의 주기로 도포를 시행하였을 때 좋은 효과를 얻을 수 있었다.

Keywords

References

  1. Gorelick L, Geiger AM, Gwinnett AJ : Incidence of white spot formation after bonding and banding. Am J Orthod, 81:323-332, 1982.
  2. Silverstone LM : Observation on the dark zone in early enamel caries and artificial like lesions. Caries Res, 1:267-274, 1967.
  3. 임성수, 김용기 : Fluoride varnish 도포가 초기 법랑질 우식 병소의 재석회화에 미치는 영향에 관한 연구. 대한소아치과학회지, 20:131-144, 1993.
  4. 대한소아치과학회 : 소아, 청소년 치과학, 4판. 신흥인터내셔날, 서울, 160-174, 2007.
  5. Seppa L : Fluoride content of enamel during treatment and 2 years after discontinuation of treatment with fluoride varnishes. Caries Res, 18:278-271, 1984. https://doi.org/10.1159/000260777
  6. ten Cate JM, Arends J : Remineralization of artificial enamel lesions in vitro. Caries Res, 15:60-69, 1981. https://doi.org/10.1159/000260501
  7. Gelhard TBFM, Arends J : In vivo remineralization of artificial substance lesions in human enamel. J Biol Bucc, 12:49-57, 1984.
  8. Marinelli CB, Donly KJ, Welfel JS, et al. : An in vitro comparison of three fluoride regimens on enamel remineralization. Caries Res, 31:418-422, 1997. https://doi.org/10.1159/000262432
  9. Varughese, Moreno EC : Crystal growth of calcium apatites in dilute solutions containing fluorides. Cal Tissue Int, 33:431-439, 1981. https://doi.org/10.1007/BF02409467
  10. 안호영, 이광희, 김대업 : 산성 음료에 의한 법랑질의 침식과 인공타액에 의한 재광화. 대한소아치과학회지, 29:84-91, 2002.
  11. Pertersson LG : Fluoride mouthrinses and fluoride varnishes. Caries Res, 27:35-42, 1993. https://doi.org/10.1159/000261600
  12. Retief DH, Sorvas PG, Bradley EL, et al. : In vitro fluoride uptake, distribution and retention by human enamel after 1 and 24 hour application of various topical fluoride agents. J Dent Res, 59:573-582, 1980.
  13. Samir E, Bishara, Adam WO : White spot lesions : Formation, prevention, and treatment. Seminars in Orthod, 14:174-182, 2008. https://doi.org/10.1053/j.sodo.2008.03.002
  14. Robert NS : Effect of fluoride varnish on demineralization around orthodontic brackets. Seminars in Orthod, 14:194-199, 2008. https://doi.org/10.1053/j.sodo.2008.03.004
  15. Domoto P, Weinstrin P, Leroux B, et al. : White spots caries in Mexican-American toddlers and parental preference of various strategies. J of Dent for children, 61:342-346, 1994.
  16. Kaste LM, Selwitz RH, Oldakowski RJ, et al. : Coronal caries in the primary and permanent dentition of children and adolescents 1-17 year of age : United States, 1988-1991. J Dent Res, 75:631-642, 1996.
  17. Hallonsten AL, Wendt LK, Majare I, et al. : Dental caries and prolonged breast-feeding in 18-month-old Swedish children. Int J Paediatr Dent, 5:149-155, 1995.
  18. Fejerskov O : Changing paradigms in concepts on dental caries: consequences for oral health care. Caries Res, 38:182-191, 2004. https://doi.org/10.1159/000077753
  19. Dean HT, Arnold FA, Elvove E : Domestic water and dental caries. V. Additional studies of the relation of fluoride in domestic waters to dental caries experience in 4,425 white children aged 12 to 14 years, of 13 cities in 4 states. Publ Hth Rep, 57:1155-1179, 1942. https://doi.org/10.2307/4584182
  20. Heilman JR, Jordan TH, Warwick R, et al. : Remineralization of root surfaces demineralized in solutions of differing fluoride levels. Caries Res, 31:423-428, 1997. https://doi.org/10.1159/000262433
  21. Heuser H, Schmidt HFM : Zahnkariesprophylaxe durch tiefen IImpragnierung des Zahnschmelzes mit Fluor-lack. Stoma, 21:91-100, 1968.
  22. Featherstone JDB, Glena R, Shariati M, et al. : Dependence of in vitro demineralization of apatite and remineralization of dental enamel on fluoride concentration. J Dent Res, 69:620-625, 1990.
  23. Tveit AB : Fluoride uptake by enamel surfaces, root surfaces and cavity walls following application of a fluoride varnish in vitro. Caries Res, 14:315-323, 1980. https://doi.org/10.1159/000260470
  24. Rozier RG, Sutton BK, Bawden JW, et al. : Prevention of early childhood caries in North Carolina medical practices : implications for research and practice. J Dent Educ, 67:876-885, 2003.
  25. Ekstrans J, Koch G, Pertersson LG : Plasma fluoride concentration and urinary fluoride excretion in children following application of the fluoride-containing varnish Duraphat. Caries Res, 14:185-189, 1980. https://doi.org/10.1159/000260452
  26. ten Cate JM : In vitro studies on the effects of fluoride on demineralization and remineralization. J Dent Res, 69:614-619, 1990.
  27. 김종빈, 김종수, 유승훈 : DIFOTI 영상 최적화를 위한 광량에 대한 연구. 대한소아치과학회지, 37:13-23, 2010.
  28. Groeneveld A, Jongebloed W, Arends J : The mineral content of decalcified surface enamel. A combined microprobe-quantitative microradiography study. Caries Res, 8:267-274, 1974. https://doi.org/10.1159/000260115
  29. Aoba T, Okazaki M, Takahashi J, et al. : X-ray diffraction study on remineralization using synthetic hydroxyapatite pellets. Caries Res, 12:223-230, 1978. https://doi.org/10.1159/000260336
  30. Darling AI : Some observations on amelogenesis imperfecta and calcification of the dental enamel. Proc R Soc Med, 49:759-765, 1956.
  31. Featherstone JDB, ten Cate JM, Shariati M, et al. : Comparison of artificial caries-like lesions by quantitative microradiography and microhardness profiles. Caries Res, 17:385-391, 1983. https://doi.org/10.1159/000260692
  32. Haikel Y, Frank RM, Voegel JC : Scanning electron microscopy of the human enamel surface layer of incipient carious lesions. Caries Res, 17:1-13, 1983.
  33. 한원섭, 금기연, 이찬영 : 인공 치아 우식의 재광화에 미치는 불소의 영향. 대한치과 보존 학회지, 21:161-173, 1996.
  34. Lammers PC, Borggreven JMPM, Driessens FCM : Influence of fluoride on in vitro remineralization of artificial subsurface lesions determined with a sandwich technique. Caries Res, 24:81-85, 1990. https://doi.org/10.1159/000261244
  35. 박정원, 허복, 이찬영 : 유기산 완충 용액의 포화도가 법랑질 및 상아질의 재광화에 미치는 영향과 수산화인회석의 AFM 관찰. 대한치과보존학회지, 25:459-473, 2000.
  36. 정희민, 김용기 : 수종의 구강위생 방법에 따른 인공 초기우식 법랑질의 재석회화에 관한 비교 생체연구. 대한소아치과학회지, 18:94-108, 1991.