Sensor Calibration of a Helmet MEG System

헬멧형 뇌자도 장치의 센서 교정

  • Kwon, H. (Brain and Cognition Measurement Lab., Korea Research Institute of Standards and Science) ;
  • Kim, K. (Brain and Cognition Measurement Lab., Korea Research Institute of Standards and Science) ;
  • Yu, K.K. (Brain and Cognition Measurement Lab., Korea Research Institute of Standards and Science) ;
  • Kim, J.M. (Brain and Cognition Measurement Lab., Korea Research Institute of Standards and Science) ;
  • Lee, Y.H. (Brain and Cognition Measurement Lab., Korea Research Institute of Standards and Science)
  • Received : 2010.09.07
  • Accepted : 2010.10.05
  • Published : 2010.10.31

Abstract

We have developed a whole-head MEG system for basic brain research and clinical application. The sensor system consists of a 152 SQUID gradiometer array oriented and located in a suitable way to cover a whole head of the human. The system measures magnetic fields generated by neuronal currents in the brain to get information on the brain activities. For this purpose, the field sensitivity determined by the position, orientation and geometry of the pickup coil as well as amplification factor of the electronic circuits should be known precisely. However, the position and orientation of the pickup coil might be changed from the designed specifications during cool down of the dewar and it is necessary to characterize the field sensitivity. In this study, we made calibration systems to determine the actual position and orientation of the 152 pickup coils and compared the localization results of the N100m source in the auditory cortex.

Keywords

References

  1. M. Hamalainen, R. Hari, R. J. Ilmoniemi, J. Knuutila, O. V. Lounasmaa, "Magnetoencephalography-theory, instrumentation, and applications to noninvasive studies of the working human brain", Rev. Mod. Phys. 65, 413-497 (1993). https://doi.org/10.1103/RevModPhys.65.413
  2. D. M. Goldenholz, S. P. Ahlfors, M. S. Hmlinen et al, "Mapping the Signal-To-Noise-Ratios of Cortical Sources in Magnetoencephalography and Electroencephalography", Human Brain Mapping, 30, 1077-1086 (2009). https://doi.org/10.1002/hbm.20571
  3. Y. H. Lee, H. Kwon, K. K. Yu, J. M. Kim and K. Kim, "A helmet-type magnetoencephalography system having compact axial gradiometer structure", 제24회 일본생체자기학회 학술논문집, 22 (2009).
  4. W. Goffe, G. Ferrier and J. Rogers, "Global Optimization of statistical functions with simulated annealing", J. Economet. 60, 65-100 (1994). https://doi.org/10.1016/0304-4076(94)90038-8