대한치과마취과학회지 (Journal of The Korean Dental Society of Anesthesiology)

  • 제10권2호
  • /
  • Pages.172-177
  • /
  • 2010
  • /
  • 1598-4044(pISSN)
  • /
  • 2383-7039(eISSN)
대한치과마취과학회 (The Korean Dental Society of Anesthsiology)
권호 표지

치과 국소마취와 관련된 하치조신경과 설신경 손상에 대한 연구

Study for Inferior Alveolar and Lingual Nerve Damages Associated with Dental Local Anesthesia

  • 이병하 (한양대학교 의과대학 치과학교실 구강악안면외과) ;
  • 임태윤 (한양대학교 의과대학 치과학교실 구강악안면외과) ;
  • 황경균 (한양대학교 의과대학 치과학교실 구강악안면외과) ;
  • 서민석 (한양대학교 의과대학 치과학교실 치과보존과) ;
  • 박창주 (한양대학교 의과대학 치과학교실 구강악안면외과)
  • Lee, Byung-Ha (Division of Oral and Maxillofacial Surgery, Department of Dentistry, College of Medicine, Hanyang University) ;
  • Im, Tae-Yun (Division of Oral and Maxillofacial Surgery, Department of Dentistry, College of Medicine, Hanyang University) ;
  • Hwang, Kyung-Gyun (Division of Oral and Maxillofacial Surgery, Department of Dentistry, College of Medicine, Hanyang University) ;
  • Seo, Min-Seock (Division of Conservative Dentistry, Department of Dentistry, College of Medicine, Hanyang University) ;
  • Park, Chang-Joo (Division of Oral and Maxillofacial Surgery, Department of Dentistry, College of Medicine, Hanyang University)
  • 투고 : 2010.12.09
  • 심사 : 2010.12.21
  • 발행 : 2010.12.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Background: Damages of trigeminal nerve, particularly inferior alveolar nerve and lingual nerve, could occur following dental procedures. In some cases, nerve damage may happen as a complication of the local anesthetic injection itself and not of the surgical procedure. Methods: From September 2006 to August 2010, 5 cases of inferior alveolar nerve and lingual nerve damages, which were assumed to happen solely due to local anesthesia, were reviewed. All cases were referred to Division of Oral and Maxillofacial Surgery, Department of Dentistry, Hanyang University Medical Center for legal authentication in the process of criminal procedure. Results: In all five cases, patients complained of altered sensation occurred in the distribution of the inferior alveolar or lingual nerve following block anesthesia. The local anesthetics were 2% lidocaine with 1 : 100,000 epinephrine and the amount of local anesthetics, which were used during injection, were varied. Most of patients experienced the electric stimulation during injection. Recovery was poor and professional supportive care was mostly absent. Conclusions: Dental practitioners should consider that the surgical procedure caused the trigeminal nerve damage, however, dental local anesthesia for inferior alveolar nerve and lingual nerve could be one of the causes for damages. The various mechanisms for nerve damages by local anesthesia are thoroughly discussed.

키워드

참고문헌

  1. Alling CC: Dysesthesia of the lingual and inferior alveolar nerves following third molar surgery. J Oral Maxillofac Surg 1986; 44: 454-7. https://doi.org/10.1016/S0278-2391(86)80010-6
  2. Bruce RA, Frederickson GC, Small GS: Age of patients and morbidity associated with mandibular third molar surgery. J Am Dent Assoc 1980; 101: 240-5. https://doi.org/10.14219/jada.archive.1980.0183
  3. Gentili F, Hudson AR, Hunter D: Clinical and experimental aspects of injection injuries of peripheral nerves. Can J Neurol Sci 1980; 7: 143-51. https://doi.org/10.1017/S0317167100023520
  4. Gentili F, Hudson AR, Hunter D, Kline DG: Nerve injection injury with local anesthetic agents: a light and electron microscopic, fluorescent microscopic, and horseradish peroxidase study. Neurosurgery 1980; 6: 263-72. https://doi.org/10.1227/00006123-198003000-00007
  5. Goldberg MH, Nemarich AN, Marco WP: Complications after mandibular third molar surgery: a statistic analysis of 500 consecutive procedures in private practice. J Am Dent Assoc 1985; 111: 277-9. https://doi.org/10.14219/jada.archive.1985.0098
  6. Haas DA: Localized complications from local anesthesia. J Calif Dent Assoc 1998; 26: 677-82.
  7. Haas DA, Lennon D: A 21 year retrospective study of reports of paresthesia following local anaesthetic administration. J Can Dent Assoc 1995; 61: 319-30.
  8. Harn SD, Durham TM: Incidence of lingual nerve trauma and post injection complications in conventional mandibular block anesthesia. J Am Dent Assoc 1990; 121: 519-23. https://doi.org/10.14219/jada.archive.1990.0198
  9. Hudson AR: Injection nerve injuries. Clin Plast Surg 1984; 11: 27-30.
  10. Kalichman MW: Physiologic mechanisms by which local anesthetics may cause injury to nerve and spinal cord. Reg Anesth 1993; 18: 448-52.
  11. Kanai Y, Katsuki H, Takasaki M: Graded, irreversible changes in crayfish giant axon as manifestations of lidocaine neurotoxicity in vitro. Anesth Analg 1998; 86: 569-73. https://doi.org/10.1213/00000539-199803000-00025
  12. Kipp DP, Goldstein BH, Weiss WW: Dysesthesia after mandibular third molar surgery. A retrospective study and analysis of 1,377 surgical procedures. J Am Dent Assoc 1980; 100: 185-92. https://doi.org/10.14219/jada.archive.1980.0074
  13. Krafft TC, Hickel R: Clinical investigation in to the incidence of direct damage to the lingual nerve caused by local anaesthesia. J Craniomaxillofac Surg 1994: 22: 294-6. https://doi.org/10.1016/S1010-5182(05)80079-4
  14. Kytta J, Heinonen E, Rosenberg PH, Wahlstrom T, Gripenberg J, Huopaniemi T: Effects of repeated bupivacaine administration on sciatic nerve and surrounding muscle tissue in rats. Acta Anaesthesiol Scand 1986; 30: 625-9. https://doi.org/10.1111/j.1399-6576.1986.tb02488.x
  15. Lee WY, Park CJ, Shin TJ, Yum KW, Yoon TG, Seo KS, Kim HJ: Only tetracaine and not other local anaesthetics induce apoptosis in rat cortical astrocytes. Br J Anaesth 2009; 103: 719-25. https://doi.org/10.1093/bja/aep237
  16. Merrill RG: Prevention, treatment and prognosis of nerve injury related to the difficult impaction. Dent Clin North Am 1979; 23: 471-88.
  17. Osborn TP, Frederickson GC, Small IA, Torgeson TS: A prospective study of complications related to third molar surgery. J Oral Maxillofac Surg 1985; 43: 767-9. https://doi.org/10.1016/0278-2391(85)90331-3
  18. Park CJ, Park SA, Yoon TG, Lee SJ, Yum KW, Kim HJ: Bupivacaine induces apoptosis via ROS in the Schwann cell line. J Dent Res 2005; 84: 852-7. https://doi.org/10.1177/154405910508400914
  19. Park JH, Lee SH, Kim ST: Pharmacologic management of trigeminal nerve injury pain after dental implant surgery. Int J Prosthodont 2010; 23: 342-6.
  20. Pogrel MA: Complications of third molar surgery. Oral Maxillofac Surg Clin North Am 1990; 2: 441-51.
  21. Pogrel MA, Bryan J, Regezi J: Nerve damage associated with inferior alveolar nerve blocks. J Am Dent Assoc 1995; 126: 1150-5. https://doi.org/10.14219/jada.archive.1995.0336
  22. Pogrel MA, Kaban LB: Injuries to the inferior alveolar and lingual nerves. Calif Dent J 1993; 21: 50-4.
  23. Pogrel MA, Thamby S: Permanent nerve involvement resulting from inferior alveolar nerve blocks. J Am Dent Assoc 2004; 131: 901-7.
  24. Rayan GM, Pitha JV, Wisdom P, Brentlinger A, Kopta JA: Histologic and electrophysiologic charges following subepineurial hematoma induction in rat sciatic nerve. Clin Orthop 1988; 229: 257-64.
  25. Radwan IA, Saito S, Goto F: The neurotoxicity of local anesthetics on growing neurons: a comparative study of lidocaine, bupivacaine, mepivacaine, and ropivacaine. Anesth Analg 2002; 94: 319-24.
  26. Rud J: The split bone technique for removal of impacted mandibular third molars. J Oral Surg 1970; 28: 416-21.
  27. Schwartz U: Lingual anesthesia following mandibular odontectomy. J Oral Surg 1973; 31: 918-20.
  28. van Gool AV, Ten Bosch JJ, Boering G: Clinical consequences of complaints and complications after removal of the mandibular third molar. Int J Oral Surg 1977; 6: 29-37. https://doi.org/10.1016/S0300-9785(77)80069-0
  29. Wofford DT, Miller RI: Prospective study of dysesthesia following odontectomy of impacted mandibular third molars. J Oral Maxillofac Surg 1987; 4: 15-9.
  30. Ziccardi VB, Rivera L, Gomes J: Comparison of lingual and inferior alveolar nerve microsurgery outcomes. Quintessence Int 2009; 40: 295-301.