한국식품영양과학회지 (Journal of the Korean Society of Food Science and Nutrition)

  • 제39권3호
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  • Pages.376-382
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  • 2010
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  • 1226-3311(pISSN)
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  • 2288-5978(eISSN)
한국식품영양과학회 (The Korean Society of Food Science and Nutrition)
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천연 소재 BF-7의 어린이 장.단기 기억력 향상 효과

The Improvement of Short- and Long-term Memory of Young Children by BF-7

  • 김도희 (중앙대학교 의과대학 해부학교실) ;
  • 김옥현 (중앙대학교 의과대학 해부학교실) ;
  • 여주홍 (국립농업과학원 농업생물부 잠사양봉소재과) ;
  • 이광길 (국립농업과학원 농업생물부 잠사양봉소재과) ;
  • 박금덕 ((주)서흥캅셀) ;
  • 김대진 (중앙대학교 의과대학 해부학교실) ;
  • 정윤희 (중앙대학교 의과대학 해부학교실) ;
  • 김경용 (중앙대학교 의과대학 해부학교실) ;
  • 이원복 (중앙대학교 의과대학 해부학교실) ;
  • 윤영철 (중앙대학교 의과대학 신경과) ;
  • 정윤화 (단국대학교 자연과학대학 식품영양학과) ;
  • 이상형 (서울대학교 의과대학 신경외과) ;
  • 현주석 (중앙대학교 문과대학 심리학과)
  • Kim, Do-Hee (Dept. of Anatomy and Cell Biology, College of Medicine, Chung-Ang University) ;
  • Kim, Ok-Hyeon (Dept. of Anatomy and Cell Biology, College of Medicine, Chung-Ang University) ;
  • Yeo, Joo-Hong (Sericultural & Agricultural Materials Division, National Academy of Agricultural Science (NAAS)) ;
  • Lee, Kwang-Gill (Sericultural & Agricultural Materials Division, National Academy of Agricultural Science (NAAS)) ;
  • Park, Geum-Duck (Suheung Capsule Co. Ltd.) ;
  • Kim, Dae-Jin (Dept. of Anatomy and Cell Biology, College of Medicine, Chung-Ang University) ;
  • Chung, Yoon-Hee (Dept. of Anatomy and Cell Biology, College of Medicine, Chung-Ang University) ;
  • Kim, Kyung-Yong (Dept. of Anatomy and Cell Biology, College of Medicine, Chung-Ang University) ;
  • Lee, Won-Bok (Dept. of Anatomy and Cell Biology, College of Medicine, Chung-Ang University) ;
  • Youn, Young-Chul (Dept. of Neurology, College of Medicine, Chung-Ang University) ;
  • Chung, Yoon-Hwa (Dept. of Food Science and Nutrition, College of Natural Science, Dankook University) ;
  • Lee, Sang-Hyung (Dept. of Neurosurgery, College of Medicine, Seoul National University, SMG-SNU Boramae Medical Center) ;
  • Hyun, Joo-Seok (Dept. of Psychology, College of Liberal Arts, Chung-Ang University)
  • 발행 : 2010.03.31
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초록

본 연구는 BF-7이 어린이의 장기 및 단기 기억을 현저하게 촉진시킴을 보여주었다. 기존 임상 시험 결과를 통해 입증된 바와 같이 천연 소재인 BF-7의 안전성을 고려할 때, BF-7은 어린이 장기 및 단기 기억력, 기억유지도 및 기억의 효과적 활용 등 전반적인 기억 수행 능력 향상에 도움을 주는 매우 안전하면서 효과가 탁월한 천연소재임을 확인하였다.

It has been shown that BF-7 enhances short- and long-term memory and attention in normal person. BF-7 was addressed to clinical study for children if BF-7 is also effective to children, since accumulated verification of safety and effectiveness is needed for young ages, in special. We administered BF-7 and a placebo control to two different groups of children (7-12 years old, 9.78 on averages). Their memory enhancement was tested with Rey-Kim Memory Test for Children before and after the administration of BF-7 and a placebo, in a double blinded way. The results showed that long- and short-term memories were significantly improved by the administration of BF-7. Interestingly, the degree of memory preservation, the ability of memory application and awareness of complex thing were also significantly improved. These results indicate that BF-7 is a promising substance from natural resource improving learning and memory of children as well as cognitive function of adults

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참고문헌

  1. Chae HS, Kang YK, Shin YK, Lee HJ, Yu JI, Lee KG, Yeo JH, Kim YS, Sohn DS, Kim KY, Lee WB, Lee SH, Kim SS. 2004. The role of BF-7 on neuroprotection and enhancement of cognitive function. Korean J Physiol Pharmacol 8: 173-179.
  2. Lee SH, Kim YS, Kang YK, Kwon OS, Shin YK, Song JH, Lee MY, Lee KG, Yeo JH, Lee WB, Lee TJ, Kim SS. 2004. The improvement of learning and memory ability of normal persons by BF-7. Korean J Physiol Pharmacol 8: 307-312.
  3. Lee JY, Lee SH, Sung JJ, Kim ET, Cho HJ, Kim KH, Kang YK, Kim SS, Kwon OS, Lee WB. 2005. The effect of BF-7 on the ischemia-induced learning and memory deficits. Korean J Anat 38: 181-188.
  4. Lee MY, Lee SH, Lee JS, Min KJ, Lee KG, Yeo JH, Kwon HJ, Lee JK, Kang YK, Lee DY, Chung YH, Kim KY, Kim SS, Lee WB. 2004. Improved memory function and protected neuron from oxidative stress. Korean J Phys Anthropol 17: 313-320. https://doi.org/10.11637/kjpa.2004.17.4.313
  5. Kim DK, Lee JY, Sung JJ, Kim ET, Kim YS, Kwon OS, Yun YC, Lee TJ, Kang YK, Chung YH, Kim SS, Kim KY, Lee WB. 2004. The role of BF-7 on enhancement of memory and cognitive function. Korean J Anat 37: 519-527.
  6. Seo SG, Kim HK. 2004. Frontal-executive functions in schizophrenic patients. Korean J Psychol 23: 23-43.
  7. Kim DH, Lee HJ, Choi G, Kim OH, Lee KG, Yeo JH, Lee JY, Lee SH, Youn YC, Lee JH, Paik HD, Lee WB, Kim SS, Jung HY. 2009. Milk containing BF-7 enhances the learning and memory, attention, and mathematical ability of normal persons. Korean J Food Sci Animal Resources 29: 278-282. https://doi.org/10.5851/kosfa.2009.29.2.278
  8. Kim DH, Lee HJ, Lee KG, Yeo JH, Lee JY, Youn YC, Paik HD, Lee MY, Kim DJ, Chung YH, Kim KY, Lee WB, Kim SS, Jung HY. 2009. Milk with brain factor-7 (BF-7 milk) enhances attention and cognition in normal persons. Milchwissenschhaft 64: 300-304.
  9. Kim HK. 1999. Rey-Kim memory test: manual. Neuropsychology Publishing Co., Daegu, Korea. p 215-230.
  10. Kim HK. 2005. Rey-Kim memory test for children: manual. Neuropsychology Publishing Co., Daegu, Korea. p 113-127.
  11. Shiffrin RM. 1976. Capacity limitations in information processing, attention, and memory. In Handbook of learning and cognitive processes. Estes WK, ed. Erlbaum, Hillsdale, New Jersey, USA. p 20-53.
  12. Shiffrin RM, Atkinson RC. 1969. Storage and retrieval processes in long-term memory. Psychol Rev 76: 179-193. https://doi.org/10.1037/h0027277
  13. Baddeley AD. 1986. Working memory. Oxford University Press, Oxford, UK. p 34-62.
  14. Squire LR. 1987. Memory and brain. Oxford University Press, New York, USA. p 13-41.
  15. Squire LR, Zola-Morgan S. 1991. The medial temporal lobe memory system. Science 253: 1380-1386. https://doi.org/10.1126/science.1896849
  16. Calkins MW. 1898. A study of immediate and delayed recall of the concrete and of the verbal. Psychol Rev 5: 451-456. https://doi.org/10.1037/h0071176
  17. Kim HK. 2005. Kims EXIT (Executive Intelligence Test) for children: manual. Neuropsychology Publishing Co., Daegu, Korea. p 70-83.
  18. Yeo JH, Lee KG, Kweon HY, Woo SO, Ham SM, Lee YW, Kim JI, Kim SS, Demura M. 2004. Cognitive ability enhancement effects in rats by B. mori fibroin enzymatic hydrolysate. Korean J Seric Sci 46: 23-27.
  19. Rey A. 1941. L'examen psychologique dans les cas d'encephalopathie tarumatique. Archives de Psychologie 28: 286-340.
  20. Rey A. 1964. L'examen clinique en psychologie. Press Universitaire de France Press, Paris, France. p 212-270.
  21. Caselli RJ, Reiman EM, Hentz JG, Osborne D, Alexander GE, Boeve BF. 2002. A distinctive interaction between memory and chronic daytime somnolence in anymptomatic APOE e4 homozygotes. Sleep 25: 437-443.

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