The Korean Journal of Pesticide Science (농약과학회지)

The Korean Society of Pesticide Science (한국농약과학회)
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Inhibitory Effect of Extracts from 33 Medicinal Herbs Against TMV and CMV Infection

33종 생약 추훌물의 담배모자이크바이러스(TMV)와 오이모자이크바이러스(CMV)에 대한 감염 억제효과

  • Kwon, Soon-Bae (Gangwon Agricultural Research and Extension Services) ;
  • Lee, Hye-Myong (Department of Applied Biology, Kangwon National University) ;
  • Kim, Byung-Sup (Department of Plant Science, Gangneung-Wonju National University) ;
  • Choi, Jang-Kyung (Department of Applied Biology, Kangwon National University)
  • 권순배 (강원도농업기술원) ;
  • 이혜명 (강원대학교 응용생물학과) ;
  • 김병섭 (강릉원주대학교 식물생명과학과) ;
  • 최장경 (강원대학교 응용생물학과)
  • Received : 2010.05.17
  • Accepted : 2010.07.19
  • Published : 2010.09.30
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Abstract

Extracts of 33 medicinal herbs belonging to 28 different families used as precious resources in the Northeast Asia were tested for their antiviral activities against two major plant viruses. Twenty one methanol extracts from 19 different families were found to have a antiviral activity against tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV) when tested on indicator plants under greenhouse conditions. Most of these extracts have weak activities at the concentration used. But the methanol extracts of Phellinus linteus exhibited potent ($98.7{\pm}1.3%$) antiviral activity against TMV infection and also showed $97.2{\pm}2.2%$ activity against CMV infection. The methanol extracts of the gall of Rhus javanica also showed strong inhibitory efficacy over $98.7{\pm}1.1%$ against TMV or CMV infection. Further research is needed to elucidate the active constituents of these medicinal herbs which may be useful in the development of new and effective antiviral agent against plant viruses.

동북아시아 지역에서 전통적으로 진귀하게 사용되어온 생약자원 28과 33종의 추출물을 이용하여 주요 식물바이러스에 대한 감염억제활성을 조사하였다. 온실 생물검정 시험결과, 19과 21종의 메탄올 추출물이 담배모자이크바이러스(TMV)와 오이모자이크바이러스(CMV)에 대하여 항바이러스 활성을 보였다. 대부분의 공시한 사료들은 약한 항바이러스 활성은 보였으나, 목질진흙버섯의 메탄올 추출물은 TMV에 대하여 $98.7{\pm}1.3%$의 강한 항바이러스 활성을 보였다. 이는 CMV에 대하여도 $97.2{\pm}2.2%$의 높은 활성을 보였다. 또한, 오배자의 메탄올 추출물은 TMV 및 CMV에 대하여 $98.7{\pm}1.1%$이상의 억제효과를 보였다. 금후의 연구에서는 효과적이고 새로운 형태의 식물바이러스 방제제 개발에 있어서 매우 유용할 수 있는 이들 선발된 생약자원 유래의 항바이러스 활성물질의 구명이 필요하다.

Keywords

References

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