"Extended" Distal Pancreatectomy with Segmental Resection of Both Splenic Vessels; Extended Warshaw's Procedure

  • Kim, Dong-Hyun (Department of Surgery, Yonsei University Wonju College of Medicine) ;
  • Kang, Chang-Moo (Department of Surgery, Yonsei University College of Medicine) ;
  • Hwang, Ho-Kyoung (Department of Surgery, Yonsei University College of Medicine) ;
  • Lee, Woo-Jung (Department of Surgery, Yonsei University College of Medicine) ;
  • Chi, Hoon-Sang (Department of Surgery, Yonsei University College of Medicine)
  • 발행 : 2010.12.31

초록

Purpose: We would like to assess the safety and feasibility of extended spleen-preserving distal pancreatectomy with segmental resection of both splenic vessels (SPDP-SRSV) in patients with large, benign and borderline malignant pancreas body tumors. Methods: We encountered seven extended SPDP-SRSV cases from January 2006 to March 2010. Among them, three were excluded due to combined pylorus-reserving pancreaticoduodenectomy (PPPD). For the extended surgical technique, the pancreas was divided above the confluence of the superior mesenteric vein-splenic vein-portal vein (SMV-SV-PV), and vascular control was achieved at the origin of the splenic artery and the junction of the splenic vein with the SMV. The segments of both splenic vessels were then extracted along with the specimen. Results: All the patients were female with a median age of 57 years (range: 24~70 years). The median tumor size was 5.5 cm (range: 5~11 cm), the median operation time was 362 minutes (range: 337~441 min), the median estimated blood loss was 150 ml (range: 50~300 ml) and the median hospital stay was 9 days (range: 7~20 days). One patient underwent robot-assisted extended Warshaw procedures. No mortality was noted, but one partial intestinal obstruction occurred and this was resolved with conservative management. On the recent follow-up, the CT scans showed no evidence of tumor recurrence or spleen infarction, but newly developed perigastric varix was noted, but it was without variceal bleeding. Conclusion: SPDP-SRSV with division of the pancreatic neck portion above the confluence of the SMV-SV-PV in patients with large, benign and borderline malignant pancreatic body tumors appears to be an ideal approach because of the expected long-term survival and preserving the role of the spleen.

키워드

참고문헌

  1. Shoup M, Brennan MF, McWhite K, Leung DH, Klimstra D, Conlon KC. The value of splenic preservation with distal pancreatectomy. Arch Surg 2002;137:164-168. https://doi.org/10.1001/archsurg.137.2.164
  2. Robinette CD, Fraumeni JF Jr. Splenectomy and subsequent mortality in veterans of the 1939-45 war. Lancet 1977;2: 127-129.
  3. Benoist S, Dugue L, Sauvanet A, et al. Is there a role of preservation of the spleen in distal pancreatectomy? J Am Coll Surg 1999;188:255-260. https://doi.org/10.1016/S1072-7515(98)00299-3
  4. Mellemkjoer L, Olsen JH, Linet MS, Gridley G, McLaughlin JK. Cancer risk after splenectomy. Cancer 1995;75:577-583. https://doi.org/10.1002/1097-0142(19950115)75:2<577::AID-CNCR2820750222>3.0.CO;2-K
  5. Warshaw AL. Conservation of the spleen with distal pancreatectomy. Arch Surg 1988;123:550-553. https://doi.org/10.1001/archsurg.1988.01400290032004
  6. Warshaw AL. Distal pancreatectomy with preservation of the spleen. J Hepatobiliary Pancreat Sci 2010;17:808-812. https://doi.org/10.1007/s00534-009-0226-z
  7. Miura F, Takada T, Asano T, et al. Hemodynamic changes of splenogastric circulation after spleen-preserving pancreatectomy with excision of splenic artery and vein. Surgery 2005;138:518-522. https://doi.org/10.1016/j.surg.2005.04.020
  8. Rodriguez JR, Madanat MG, Healy BC, Thayer SP, Warshaw AL, Fernández-del Castillo C. Distal pancreatectomy with splenic preservation revisited. Surgery 2007;141:619-625. https://doi.org/10.1016/j.surg.2006.09.020
  9. Crippa S, Bassi C, Warshaw AL, et al. Middle pancreatectomy: indications, short- and long-term operative outcomes. Ann Surg 2007;246:69-76. https://doi.org/10.1097/01.sla.0000262790.51512.57