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The Korea Academia-Industrial cooperation Society (한국산학기술학회)
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Inhibitory effects on colonization of Streptococcus mutans by eighteen months xylitol consumption

18개월간 자일리톨 껌 저작에 따른 Streptococcus mutans의 집락 형성 억제효과

  • Park, Ji-Hye (Dept. of Preventive Dentistry, School of Dentistry, Kyungpook National University) ;
  • Ahn, Sang-Hun (Dept of Medical Dentistry, College of Medicine, Dongguk University) ;
  • Gu, Hyo-Jin (Dept. of Dental Hygiene, College of Health Sciences) ;
  • Choi, Youn-Hee (Dept. of Preventive Dentistry, School of Dentistry, Kyungpook National University) ;
  • Song, Keun-Bae (Dept. of Preventive Dentistry, School of Dentistry, Kyungpook National University)
  • 박지혜 (경북대학교 치과대학 예방치과학교실) ;
  • 안상헌 (동국대학 의과대학 치과학교실) ;
  • 구효진 (춘해보건대학 치위생과) ;
  • 최연희 (경북대학교 치과대학 예방치과학교실) ;
  • 송근배 (경북대학교 치과대학 예방치과학교실)
  • Published : 2010.01.31
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Abstract

The purpose of this study was to evaluate suppression of Streptococcus mutans(S. mutans) colonization by long-term xylitol consumption among pregnant women who can easily get bad oral hygiene status during pregnancy and breast feeding. Participants were voluntarily recruited for a pregnant women's oral health prevention program, classified into two groups(a control and a xylitol group), and then followed for 18 months. Stimulated whole saliva was collected in the afternoon(1:00-3:00 p.m.) at baseline, 6 months, 12months, and 18 months. Information regarding oral health behavior(tooth brushing frequency and regular dental visits) was obtained via a questionnaire. S. mutans counts of the xylitol group decreased considerably between baseline and the re-examinations at 6, 12, and 18 months. Although the S. mutans counts decreased for all time points compared to baseline in the control group, these differences did not reach significance except 18 months. Regular chewing of xylitol gum over a long period may lead to decrease the colony counts of S. mutans.

본 연구는 임신 및 수유기간 동안 구강위생상태가 불량해질 수 있는 임산부에 있어서 장기간의 자일리톨 섭취가 Streptococcus mutans(S. mutans) 집락수에 어떠한 영향을 미치는 지에 대해 알아보고자 하였다. 임산부구강건강 예방프로그램에 대상자를 자발적으로 모집하여 두 군(실험군과 대조군)으로 나눈 후 18개월간 추적 조사하였다. 자극성 타액은 오후시간(1:00-3:00 p.m.)에 초기, 6개월, 12개월 및 18개월에 채취하였다. 구강보건행태(잇솔질 횟수와 정기구강검진)에 관한 정보는 설문지를 통해서 얻어졌다. 타액 내 자일리톨군의 연구기간에 따른 S. mutans 평균집락수의 차이는 통계적으로 유의하였으며, 특히 연구초기에 비해 출산 후 6개월, 12개월 및 18개월 모두에서 유의한 감소를 나타내었다. 반면 대조군에서는 연구초기에 비해 출산 후 18개월에서만 유의한 감소를 나타내었다. 이상의 결과를 종합해 보면, 자일리톨의 장기적인 섭취는 구강 내 S. mutans 집락수를 감소시킴으로써 임산부들에 있어서도 치아우식증 예방효과가 나타날 수 있을 것으로 사료된다.

Keywords

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